Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Masazumi Tada"'
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Potentially cancerous cells undergo live apical extrusion from normal monolayers and vSrc expression induces this in zebrafish epithelia. Here, the authors show that vSrc coordinates cytokinetic ring formation, cell cycle progression, junctional inte
Externí odkaz:
https://doaj.org/article/8ff80693d50442bea784cc1754aca29d
Autor:
Germán Reig, Mauricio Cerda, Néstor Sepúlveda, Daniela Flores, Victor Castañeda, Masazumi Tada, Steffen Härtel, Miguel L. Concha
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The role of mechanical signals in early development are not fully understood. Here, the authors use the simplicity of early killifish embryos to show that tension arising from extra-embryonic epithelial expansion directs the spreading of mesenchymal-
Externí odkaz:
https://doaj.org/article/0b9b87f39cac4dc8b802f17c1ba4259f
Autor:
Georgios Trichas, Bradley Joyce, Lucy A Crompton, Vivienne Wilkins, Melanie Clements, Masazumi Tada, Tristan A Rodriguez, Shankar Srinivas
Publikováno v:
PLoS Biology, Vol 9, Iss 2, p e1001019 (2011)
The anterior visceral endoderm (AVE), a signalling centre within the simple epithelium of the visceral endoderm (VE), is required for anterior-posterior axis specification in the mouse embryo. AVE cells migrate directionally within the VE, thereby pr
Externí odkaz:
https://doaj.org/article/786173a495844e6b9d0a3a8c47aab12f
Autor:
Masazumi Tada
Publikováno v:
Developmental Biology. 477:1-10
Cell extrusion is a morphogenetic process in which unfit or dying cells are eliminated from the tissue at the interface with healthy neighbours in homeostasis. This process is also highly associated with cell fate specification followed by differenti
Autor:
Yusuke Ohba, Yuki Akieda, Takanobu Shirai, Ryutaro Akiyama, Yasuyuki Fujita, Yasuto Takeuchi, Yusuke Toyama, Mihoko Kajita, Takaaki Matsui, Yoichiroh Hosokawa, Masazumi Tada, Yoichiro Fujioka, Keisuke Kuromiya, Sohei Yamada, Susumu Ishikawa, Tohru Ishitani, Yukinari Haraoka, Elisa Vitiello, Rika Narumi, Nobuyuki Tanimura
Publikováno v:
Current biology. 30(4):670-681
When oncogenic transformation or apoptosis occurs within epithelia, the harmful or dead cells are apically extruded from tissues to maintain epithelial homeostasis. However, the underlying molecular mechanism still remains elusive. In this study, we
Autor:
Maria S. Balda, Ceniz Zihni, Masazumi Tada, Christian Hartmann, Klaus Ebnet, Karl Matter, Artur Ruppel, Alexis J. Haas
Publikováno v:
Cell Reports
Summary Tight-junction-regulated actomyosin activity determines epithelial and endothelial tension on adherens junctions and drives morphogenetic processes; however, whether or not tight junctions themselves are under tensile stress is not clear. Her
Autor:
Masazumi Tada, Daniel Čapek, Tamás Vicsek, Verena Ruprecht, Silvia Grigolon, Zsuzsa Ákos, Martin Behrndt, Michael Smutny, Ekaterina Papusheva, Björn Hof, Guillaume Salbreux, Carl-Philipp Heisenberg, Shayan Shamipour
Publikováno v:
Nature cell biology
During embryonic development, mechanical forces are essential for cellular rearrangements driving tissue morphogenesis. Here, we show that in the early zebrafish embryo, friction forces are generated at the interface between anterior axial mesoderm (
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
At the initial stage of carcinogenesis single mutated cells appear within an epithelium. Mammalian in vitro experiments show that potentially cancerous cells undergo live apical extrusion from normal monolayers. However, the mechanism underlying this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca272e7cf0a3872f95a0343ffa294ea
https://doi.org/10.1101/246199
https://doi.org/10.1101/246199
Autor:
Nobuhiro Kasai, Tomohiro Yamazaki, Yuta Yako, Susumu Ishikawa, Masazumi Tada, Shunsuke Kon, Takashi Hayashi, Yusuke Ohba, Mihoko Kajita, Sayaka Saitoh, Natsu Sugama, Yasuyuki Fujita, Yoichiro Fujioka, Takeshi Maruyama
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(12)
Newly emerging transformed cells are often eliminated from epithelial tissues. Recent studies have revealed that this cancer-preventive process involves the interaction with the surrounding normal epithelial cells; however, the molecular mechanisms u
Autor:
Masazumi Tada, Daniela Flores, German Reig, Victor Castañeda, Miguel L. Concha, Mauricio Cerda, Steffen Härtel, Néstor Sepúlveda
Publikováno v:
Nature Communications
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The spreading of mesenchymal-like cell layers is critical for embryo morphogenesis and tissue repair, yet we know little of this process in vivo. Here we take advantage of unique developmental features of the non-conventional annual killifish embryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff3af1c30f06bc9c14e5b7c5666bfad