Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Masazumi Kamohara"'
Autor:
Yukari Koya, Hirotsugu Tanaka, Eiji Yoshimi, Nobuaki Takeshita, Shuji Morita, Hiroki Morio, Kanako Mori, Hiroshi Fushiki, Masazumi Kamohara
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTNerve growth factor (NGF) has emerged as a key driver of pain perception in several chronic pain conditions, including osteoarthritis (OA), and plays an important role in the generation and survival of neurons. Although anti-NGF antibodies im
Externí odkaz:
https://doaj.org/article/1d317d9198cb4f5ca6596cc78d7ab4ae
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Activation of the tyrosine kinase with Ig and epidermal growth factor homology domain 2 (Tie2) receptor by angiopoietin-1 (Ang1) is critical for vascular stabilization: it promotes survival signal transduction via auto-phosphorylation and re
Externí odkaz:
https://doaj.org/article/7c2f17bac5f94a118eb826a1c4de17ce
Autor:
Yukari Koya, Hirotsugu Tanaka, Eiji Yoshimi, Nobuaki Takeshita, Shuji Morita, Hiroki Morio, Kanako Mori, Hiroshi Fushiki, Masazumi Kamohara
Publikováno v:
mAbs. 15
Nerve growth factor (NGF) has emerged as a key driver of pain perception in several chronic pain conditions, including osteoarthritis (OA), and plays an important role in the generation and survival of neurons. Although anti-NGF antibodies improve pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97dab9b9a7d7ce59e3a7ddec62b8af58
https://doi.org/10.1080/19420862.2022.2149055
https://doi.org/10.1080/19420862.2022.2149055
Autor:
Kenichi Watanabe, Masazumi Kamohara, Shigeru Miyagawa, Masao Sasai, Kazuhiko Mizukami, Hiromu Sato, Yoshiki Sawa, Kenichiro Shimatani, Atsuhiro Saito
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 320:H1124-H1135
Critical limb ischemia (CLI) is a severe state of peripheral artery disease with high unmet clinical needs. Further, there are no effective treatment options for patients with CLI. Based on preclinical study results, predicting the clinical efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2461053c5117257d87745b806ae6c4
https://doi.org/10.1152/ajpheart.00470.2020
https://doi.org/10.1152/ajpheart.00470.2020
Autor:
Tamaki Oda, Shun-ichiro Matsumoto, Mitsuyuki Matsumoto, Jun Takasaki, Masazumi Kamohara, Takatoshi Soga, Hideki Hiyama, Masato Kobori, Masao Katoh
Publikováno v:
Journal of Pharmacological Sciences, Vol 98, Iss 3, Pp 319-322 (2005)
Histamine H4 receptor is considered as a novel therapeutic target for allergic diseases. To enhance the knowledge about species difference, which is essential for drug discovery research, monkey H4 receptor was identified. Monkey H4 receptor was char
Externí odkaz:
https://doaj.org/article/6aec41691ecc4791b66100b9c197a08c
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Activation of the tyrosine kinase with Ig and epidermal growth factor homology domain 2 (Tie2) receptor by angiopoietin-1 (Ang1) is critical for vascular stabilization: it promotes survival signal transduction via auto-phosphorylation and reduces vas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284a559272c69541cd91e3dae875201a
https://doi.org/10.1038/s41598-021-93660-4
https://doi.org/10.1038/s41598-021-93660-4
Activation of the tyrosine kinase with Ig and epidermal growth factor homology domain 2 (Tie2) receptor by angiopoietin-1 (Ang1) is critical for vascular stabilization: it promotes survival signal transduction via auto-phosphorylation and reduces vas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cb2ca80f3fd487c98a4496e0b352e7e
https://doi.org/10.21203/rs.3.rs-244826/v1
https://doi.org/10.21203/rs.3.rs-244826/v1
Autor:
Yukiko Yamagishi, Kaori Fujita, Nobuaki Takeshita, Tatsuya Kawamoto, Yuki Iimori, Masayuki Tanahashi, Hiroaki Nakamura, Masazumi Kamohara, Tomonori Ozaki, Noriyuki Tsumaki
Publikováno v:
Scientific Reports
Achondroplasia is caused by gain-of-function mutations in FGFR3 gene and leads to short-limb dwarfism. A stabilized analogue of C-type natriuretic peptide (CNP) is known to elongate bone by interacting with FGFR3 signals and thus is a promising drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9682810a546c963df95a6d26eaa53b4e
https://pubmed.ncbi.nlm.nih.gov/33262386
https://pubmed.ncbi.nlm.nih.gov/33262386
Autor:
Kenichiro Shimatani, Hiromu Sato, Atsuhiro Saito, Masao Sasai, Kenichi Watanabe, Kazuhiko Mizukami, Masazumi Kamohara, Shigeru Miyagawa, Yoshiki Sawa
Publikováno v:
American Journal of Physiology: Endocrinology & Metabolism; Mar2021, Vol. 320 Issue 3, pH1124-H1135, 12p
Autor:
Ayako Matsuo, Mamoru Nagano, Masazumi Kamohara, Masato Kobori, Masao Katoh, Shunichiro Matsumoto, Kiyoshi Furuichi, Hideki Hiyama, Yasufumi Shigeyoshi, Mitsuyuki Matsumoto, Hitoshi Matsushime, Chihiro Yamazaki, Takatoshi Soga, Koh-hei Masumoto, Masanori Naito, Jun Takasaki, Hiroyuki Ishii
Publikováno v:
Proceedings of the National Academy of Sciences. 103:4140-4145
Prokineticins, multifunctional secreted proteins, activate two endogenous G protein-coupled receptors PKR1 and PKR2. From in situ analysis of the mouse brain, we discovered that PKR2 is predominantly expressed in the olfactory bulb (OB). To examine t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c116563a7907dfa724ebf5fd2ec7e8d
https://doi.org/10.1073/pnas.0508881103
https://doi.org/10.1073/pnas.0508881103