Výsledky vyhledávání - "Masazumi Iwashita"

4″-Sulfation Is the Major Metabolic Pathway of Epigallocatechin-3-gallate in Humans: Characterization of Metabolites, Enzymatic Analysis, and Pharmacokinetic Profiling

Autor: Akane Hayashi, Shimpei Terasaka, Yuko Nukada, Akiyo Kameyama, Masayuki Yamane, Ryuta Shioi, Masazumi Iwashita, Kohjiro Hashizume, Osamu Morita

Publikováno v: Journal of agricultural and food chemistry. 70(27)

Epigallocatechin-3-gallate (EGCG), a major green tea polyphenol, has beneficial effects on human health. This study aimed to elucidate the detailed EGCG sulfation process to better understand its phase II metabolism, a process required to maximize it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ee382cc3210678609e38f1028dd863
https://pubmed.ncbi.nlm.nih.gov/35786898

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Efficient and diversity-oriented total synthesis of Riccardin C and application to develop novel macrolactam derivatives

Autor: Shigeru Ito, Shinya Fujii, Hiroyuki Kagechika, Masazumi Iwashita, Tomoya Hirano

Publikováno v: Tetrahedron. 67:6073-6082

Riccardin C (RC, 1) is a macrocyclic bis(bibenzyl) natural product exhibiting remarkable biological activity as a nuclear liver X receptors (LXRs) ligand and a lipid metabolism mediator. RC is expected to be a lead compound to develop drugs for ather

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40e814a5737539ea26b5b7f28a23b29c
https://doi.org/10.1016/j.tet.2011.06.018

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Synthesis and evaluation of lysophosphatidylserine analogues as inducers of mast cell degranulation. Potent activities of lysophosphatidylthreonine and its 2-deoxy derivative

Autor: Masafumi Tsujimoto, Taro Nonomura, Yuko Otani, Mayuko Ishida, Kumiko Makide, Yoshimasa Misumi, Junken Aoki, Hiroyuki Arai, Masazumi Iwashita, Tomohiko Ohwada, Ryo Taguchi

Publikováno v: Journal of medicinal chemistry. 52(19)

In response to various exogenous stimuli, mast cells (MCs) release a wide variety of inflammatory mediators stored in their cytoplasmic granules and this release initiates subsequent allergic reactions. Lysophosphatidylserine (lysoPS) has been known

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c72f08c31a6600b3361441832012d68f
https://pubmed.ncbi.nlm.nih.gov/19743861

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Akademický článek

Synthesis and Evaluation of Lysophosphatidylserine Analogues as Inducers of Mast Cell Degranulation. Potent Activities of Lysophosphatidylthreonine and Its 2-Deoxy Derivative.

Autor: Masazumi Iwashita, Kumiko Makide, Taro Nonomura, Yoshimasa Misumi, Yuko Otani, Mayuko Ishida, Ryo Taguchi, Masafumi Tsujimoto, Junken Aoki, Hiroyuki Arai, Tomohiko Ohwada

Publikováno v: Journal of Medicinal Chemistry; Oct2009, Vol. 52 Issue 19, p5837-5863, 27p

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