Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Masayuki Takechi"'
Publikováno v:
The Journal of pharmacy and pharmacology. 67(1)
Objectives We tested if modulation of cytosolic K+ levels by ouabain, an inhibitor of Na+/K+-ATPase, exerts cytoprotection against distinct stressful stimuli in human leukemic cells. Methods The cytosolic K+, Na+ or Ca2+ levels and the cytotoxicity w
Publikováno v:
Phytotherapy Research. 17:83-85
Comparisons of the biological activities of diosgenyl (DIO) beta-D-xylopyranosyl- (1 --> 2)-alpha-D-glucopyranoside (2DXalpha) and beta-D-glucopyranosyl- (1 --> 3)-beta-D-glucopyranoside (3GLbeta) or methyl glycyrrhetinate (GAM) 2DXalpha and 3GLbeta
Autor:
Shinya Uejima, Yoshiya Ohno, Kazue Masuko, Yoshiyuki Hashimoto, Takashi Masuko, Masayuki Takechi, Hideki Yagi
Publikováno v:
Cancer science. 102(1)
Cell-surface molecules containing growth factor receptors, adhesion molecules and transporter proteins are often over-expressed in various cancer cells, and could be regarded as suitable targets for therapeutic monoclonal antibodies (mAb). Anti-cance
Publikováno v:
Phytochemistry. 41:125-127
The antiviral, cytotoxic and anti-ATPase activities of 14 synthetic bufalyl glycosides were compared with each other. Among these glycosides, the activities of the gentiobioside and the melibioside were much weaker than those of the others. On the ot
Publikováno v:
Phytochemistry. 41:121-123
The haemolytic and antifungal activities of synthetic diosgenyl, tigogenyl, hecogenyl, methyl oleanolate, methyl ursolate and methyl glycyrrhetinate glycosides were compared with each other. Both activities of the steroid glycosides were generally pa
Autor:
Masayuki Takechi, Yasuo Tanaka
Publikováno v:
Phytochemistry. 37:1421-1423
Antiviral, cytotoxic and anti-ATPase activities of 14 synthetic digitoxigenyl glycosides were compared with each other. The activities of those containing gentiobioside and melibioside were much weaker than the others. On the other hand, the three ac
Autor:
Yasuo Tanaka, Masayuki Takechi
Publikováno v:
Phytochemistry. 34:675-677
From 15 synthetic methyl ursolate glycosides, the di- and tri-glycosides showed much higher haemolytic activity than the monoglycosides. The beta-gentiobioside and the beta-maltotrioside exhibited much stronger antibacterial (Staphylococcus aureus) o
Autor:
Yasuo Tanaka, Masayuki Takechi
Publikováno v:
Phytochemistry. 32:1173-1175
Of 15 synthetic methyl glycyrrhetate glycosides, the monoglycosides having CH 2 OH-6 or Me-6 in their sugar moieties and the diglycosides having a (1→4) linkage between the sugar residues showed higher haemolytic activities than the others. The β-
Autor:
Masayuki Takechi, Yasuo Tanaka
Publikováno v:
Phytochemistry. 31:3789-3791
Publikováno v:
Biologicalpharmaceutical bulletin. 21(11)
Comparisons of the biological activities of diosgenyl, methyl glycyrrhetinate or digitoxigenyl 3-O-beta-L-xylopyranosyl-(1-->6)-beta-D-glucopyranoside with those of other previously tested glycosides confirmed our assumption that both the hemolytic a