Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Masayuki Ohkura"'
Autor:
Naoto Takahashi, Jorge E. Cortes, Emiko Sakaida, Kenichi Ishizawa, Takaaki Ono, Noriko Doki, Itaru Matsumura, Valentín García-Gutiérrez, Gianantonio Rosti, Chiho Ono, Masayuki Ohkura, Yusuke Tanetsugu, Andrea Viqueira, Tim H. Brümmendorf
Publikováno v:
International Journal of Hematology. 115:838-851
Bosutinib has been investigated in multiple clinical trials globally, including Japan, for treatment of chronic myeloid leukemia (CML). A pooled analysis of seven Pfizer-sponsored clinical trials evaluated the safety of bosutinib in Japanese (n = 138
Publikováno v:
Kansenshogaku Zasshi. 96:15-24
Autor:
Mie Suzuki, Hidetoshi Hayashi, Makoto Nishio, Gerson Peltz, Takashi Nagasawa, Toyoaki Hida, Takashi Seto, Kei Fukuhara, Masayuki Ohkura, Miyako Satouchi, Yasushi Goto, Holger Thurm, Masahiro Morise, Naoyuki Nogami, Toshiaki Takahashi, Seiji Niho, Jun Sakakibara-Konishi
Publikováno v:
Cancer Science
Lorlatinib is a potent, brain‐penetrant, third‐generation anaplastic lymphoma kinase (ALK)/ROS proto‐oncogene 1 (ROS1) tyrosine kinase inhibitor (TKI) that is active against most known resistance mutations. This is an ongoing phase 1/2, multina
Autor:
Tontanai Numbenjapon, Young Rok Do, Jorge E. Cortes, Liang Piu Koh, Dae Young Zang, Charles Chuah, Tim H. Brümmendorf, Kiat Hoe Ong, Masayuki Ohkura, Andrea Viqueira, Chiho Ono
Publikováno v:
International journal of hematology. 114(1)
Bosutinib is approved in the United States, Europe, Japan, and other countries for treatment of newly diagnosed chronic phase (CP) chronic myeloid leukemia (CML), and CML resistant/intolerant to prior therapy. In the phase 3 BFORE trial (Clinicaltria
Publikováno v:
Clinical Therapeutics.
Purpose This prospective analysis of the Japanese subpopulation of the varenicline reduce to quit study was conducted to evaluate whether results for Japanese participants were consistent with the full study population. Methods Patients received vare
Publikováno v:
Clinical Therapeutics. 36:918-927
BackgroundThe efficacy of the smoking-cessation agent varenicline has been reported in Asian smokers; however, few studies have investigated factors that contribute to lapse and relapse.ObjectiveThis post hoc analysis aimed to identify predictors of
Autor:
Masayuki Ohkura, Masayuki Hino, Naohiro Sekiguchi, Naoto Takahashi, Itaru Matsumura, Emiko Sakaida, Kenichi Ishizawa, Yuichiro Koide, Shin Fujisawa, Yusuke Tanetsugu, Takaaki Ono, Kei Fukuhara
Publikováno v:
Blood. 134:4159-4159
Background: Bosutinib, a Src/Abl tyrosine kinase inhibitor, is approved at a starting dose of 500 mg once daily (QD) in many countries, including Japan, for patients with Philadelphia chromosome-positive (Ph+) chronic phase (CP), accelerated phase (A
Publikováno v:
Modern Rheumatology. 23:1108-1115
To assess the long-term safety and efficacy of pregabalin for the treatment of Japanese patients with fibromyalgia (FM). This 53-week, open-label extension study was conducted at 20 study sites in Japan in patients with FM who had completed a precedi
Autor:
Masayuki Ohkura, Makoto Suzuki, Hiroyoshi Ohta, Akihiro Kaneko, Katsuyuki Machii, Ken‘ichi Saito
Publikováno v:
Clinical Therapeutics. 34:314-328
Although third mandibular molar extraction is a widely used and validated model of acute pain for evaluating analgesic efficacy, a large proportion of patients experience moderate or severe pain following this procedure and require analgesia. Current
Autor:
Masayuki Ohkura, Toshinari Kamakura
Publikováno v:
Japanese Journal of Applied Statistics. 40:41-51
ロジスティック回帰モデルを小標本かつ応答変数発現確率が高い条件下または低い条件下で用いる場合,完全分離または準完全分離が生じていないかを確認することが重要である.完全