Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Masayuki Nakanishi"'
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101702- (2024)
ProNGF (nerve growth factor) is a precursor of NGF and a signaling peptide exerting opposite effects on neuronal cells, i.e., apoptotic or neuritogenic. The conflicting biological activity of proNGF depends on the relative levels of two membrane rece
Externí odkaz:
https://doaj.org/article/7e766c5b0f2c4b238e12f38f7eff565d
Autor:
Atsushi, Sawamoto, Kiko, Doi, Yoshiaki, Amakura, Masayuki, Nakanishi, Satoshi, Okuyama, Mitsunari, Nakajima
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1867:130277
Coffee consumption has been shown to reduce the risk of developing type 2 diabetes mellitus (T2DM) in humans; however, the exact mechanism is not completely understood. Here, we demonstrate that N-caffeoyltryptophan (CTP), an ingredient of coffee, en
Publikováno v:
Experimental Parasitology. 200:24-29
Cases of human African trypanosomiasis caused by infection with a protozoan parasite, Trypanosoma brucei, are decreasing due to enhanced surveillance and control. However, effective and safe treatments for this disease are still needed. In this study
Autor:
Satoshi Okuyama, Asami Kanazaki, Yoshiaki Amakura, Masayuki Nakanishi, Morio Yoshimura, Nahoko Uchiyama, Takashi Hakamatsuka, Mitsunari Nakajima, Atsushi Sawamoto
Publikováno v:
European journal of pharmacology. 909
Inducible brown-like adipocytes, also known as beige adipocytes, dissipate energy through thermogenesis. Although recent reports suggest that silent information regulator 2 homolog 1 (SIRT1) promotes beige adipocyte differentiation (beiging), the act
Autor:
Coh-ichi Nihei, Masayuki Nakanishi
Publikováno v:
Parasitology International. 84:102379
Membrane and secretory proteins are synthesized by ribosomes and then enter the endoplasmic reticulum (ER) where they undergo glycosylation and quality control for proper folding. Subsequently, proteins are transported to the Golgi apparatus and then
Publikováno v:
European Journal of Pharmacology. 865:172758
3,5,6,7,8,3',4'-heptamethoxyflavone (HMF), a naturally occurring polymethoxyflavone found in citrus peel, is known to have neuroprotective, anti-inflammatory, and immunomodulatory effects. However, the effects of HMF on adipogenesis remain unclear. H
Publikováno v:
International Journal of Pharmacology. 11:243-247
Publikováno v:
Japanese Journal of Applied Physics. 58:035002
Autor:
Yoshio Kusakabe, Masayuki Nakanishi, Tomonobu Umeda, Yukio Kitade, Nobutada Tanaka, Kazuo T. Nakamura
Publikováno v:
YAKUGAKU ZASSHI. 133:527-537
The human malaria parasite Plasmodium falciparum is responsible for the death of more than a million people each year. The emergence of strains of this malaria parasite resistant to conventional drug therapy has stimulated the search for antimalarial
Autor:
Nobutada Tanaka, Yukio Kitade, Yoshio Kusakabe, Ken-ichi Aoki, Masayuki Nakanishi, Chiharu Fukumi, Kazuo T. Nakamura, Arayo Haga
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 66:333-336
Phosphoglucose isomerase (PGI) is a key enzyme in glycolysis and glycogenesis that catalyses the interconversion of glucose 6-phosphate (G6P) and fructose 6-phosphate (F6P). For crystallographic studies, PGI from the human malaria parasite Plasmodium