Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Masayuki, X. Mori"'
Autor:
Masayuki X. Mori, Ryo Okada, Reiko Sakaguchi, Hideharu Hase, Yuko Imai, Onur K. Polat, Satoru G. Itoh, Hisashi Okumura, Yasuo Mori, Yasushi Okamura, Ryuji Inoue
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2 or PIP2) regulates the activities of numerous membrane proteins, including diacylglycerol(DAG)-activated TRPC3/6/7 channels. Although PIP2 binding is known to support DAG-activated TRP channel
Externí odkaz:
https://doaj.org/article/f7c90b4d91374713a6e8dee08565a3d1
Autor:
Mica Ohara-Imaizumi, Kyota Aoyagi, Hajime Yamauchi, Masashi Yoshida, Masayuki X. Mori, Yamato Hida, Ha Nam Tran, Masamichi Ohkura, Manabu Abe, Yoshihiro Akimoto, Yoko Nakamichi, Chiyono Nishiwaki, Hayato Kawakami, Kazuo Hara, Kenji Sakimura, Shinya Nagamatsu, Yasuo Mori, Junichi Nakai, Masafumi Kakei, Toshihisa Ohtsuka
Publikováno v:
Cell Reports, Vol 26, Iss 5, Pp 1213-1226.e7 (2019)
Summary: Pancreatic β cells secrete insulin by Ca2+-triggered exocytosis. However, there is no apparent secretory site similar to the neuronal active zones, and the cellular and molecular localization mechanism underlying polarized exocytosis remain
Externí odkaz:
https://doaj.org/article/5c1ff8df43a5413b832a744435d040af
Autor:
Tatsuya Kida, Nobuaki Takahashi, Masayuki X. Mori, Jiacheng H. Sun, Hideto Oota, Kosuke Nishino, Takashi Okauchi, Yuta Ochi, Daisuke Kano, Ukihide Tateishi, Yasuyoshi Watanabe, Yilong Cui, Yasuo Mori, Hisashi Doi
Publikováno v:
RSC Medicinal Chemistry. 13:1197-1204
N-Methylamide derivatives of SB366791 show higher antagonistic activity against TRPV1 compared with SB366791. 11C- and 18F-labeled radiotracers of these derivatives were synthesized, and PET imaging studies using rats were performed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b523570a002cd88124dca35599ad535e
https://doi.org/10.1039/d2md00158f
https://doi.org/10.1039/d2md00158f
Autor:
Masayuki X. Mori, Ryuji Inoue
Publikováno v:
Journal of Pharmacological Sciences, Vol 126, Iss 3, Pp 186-197 (2014)
Abstract.: Phosphoinositides(4,5)-bisphosphates [PI(4,5)P2] critically controls membrane excitability, the disruption of which leads to pathophysiological states. PI(4,5)P2 plays a primary role in regulating the conduction and gating properties of io
Externí odkaz:
https://doaj.org/article/bf22c26603684d8185c282d4579c1af0
Autor:
Masayuki X. Mori, Ryo Okada, Reiko Sakaguchi, Hideharu Hase, Yuko Imai, Onur K. Polat, Satoru G. Itoh, Hisashi Okumura, Yasuo Mori, Yasushi Okamura, Ryuji Inoue
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2 or PIP2) regulates the activities of numerous membrane proteins, including diacylglycerol(DAG)-activated TRPC3/6/7 channels. Although PIP2 binding is known to support DAG-activated TRP channel activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43bc68a31aa33310f5cf431b80e5547e
https://doi.org/10.21203/rs.3.rs-1556516/v1
https://doi.org/10.21203/rs.3.rs-1556516/v1
Autor:
Masayuki X Mori, Kyohei eItsuki, Hideharu eHase, Seishirou eSawamura, Tatsuki eKurokawa, Yasuo eMori, Ryuji eInoue
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Transient receptor potential canonical (TRPC) channels are Ca2+-permeable, nonselective cation channels that carry receptor-operated Ca2+ currents (ROCs) triggered by receptor-induced, phospholipase C (PLC)-catalyzed hydrolysis of phosphatidylinosito
Externí odkaz:
https://doaj.org/article/182c38c61ecd4c77a78ecfcd4ee60687
Autor:
Yasuo Mori, Ayaka Hasegawa, Ha Nam Tran, Yosuke Funato, Daisuke Yamazaki, Toshiro Sato, Masayuki X. Mori, Hiroaki Miki
Publikováno v:
Oncogene. 38:3962-3969
CNNM4 is a Mg2+ transporter highly expressed in the colon epithelia. Its importance in regulating intracellular Mg2+ levels and cancer development has been documented, but how CNNM4 function affects the dynamic homeostasis of the epithelial tissue re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67ab30eb6d16d4520e49947cecb953cb
https://doi.org/10.1038/s41388-019-0682-0
https://doi.org/10.1038/s41388-019-0682-0
Autor:
Akira Kawanabe, Takafumi Kawai, Tomoko Yonezawa, Yasushi Okamura, Natsuki Mizutani, Masayuki X. Mori, Onur K. Polat
Publikováno v:
The Journal of General Physiology
Voltage-sensing phosphatases (VSPs) can be used to experimentally manipulate cellular phosphoinositide levels. Kawanabe et al. describe an enhanced VSP based on the zebrafish orthologue Dr-VSP and developed by the introduction of a mutation into a me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f43bd1cd25b5ced1e5d2b7101b55e2
https://doi.org/10.1085/jgp.201912491
https://doi.org/10.1085/jgp.201912491
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:2-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7145d28b0910439004ff3b66d529b4af
https://doi.org/10.1254/jpssuppl.96.0_2-b-p-160
https://doi.org/10.1254/jpssuppl.96.0_2-b-p-160
Autor:
Satoshi Hamano, Yuji Hara, Nozomi Ogawa, Tetsushi Furukawa, Seishiro Sawamura, Shunichi Shimizu, Masayuki X. Mori, Shinichiro Yamamoto, Kaori Yamaguchi, Nobuaki Takahashi, Ryuji Inoue, Yoshifumi Ueda, Yasuo Mori, Reiko Sakaguchi, Takashi Yoshida
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :OR10-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b8c1613b9b55f2ea1eda5e6d0f28af5
https://doi.org/10.1254/jpssuppl.wcp2018.0_or10-5
https://doi.org/10.1254/jpssuppl.wcp2018.0_or10-5