Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Masayuki, Iwasaki"'
Autor:
Johan Jeong, Astraea Jager, Pablo Domizi, Mara Pavel-Dinu, Linda Gojenola, Masayuki Iwasaki, Michael C. Wei, Feng Pan, James L. Zehnder, Matthew H. Porteus, Kara L. Davis, Michael L. Cleary
Publikováno v:
Blood Advances, Vol 3, Iss 19, Pp 2825-2835 (2019)
Abstract: Chromosomal rearrangements involving the mixed lineage leukemia (MLL) gene, also known as KMT2A, are often observed in human leukemias and are generally associated with a poor prognosis. To model these leukemias, we applied clustered regula
Externí odkaz:
https://doaj.org/article/0bff7eac6dd34ab39fa5dce1d7fa2b86
Autor:
Corina Schneidawind, Johan Jeong, Dominik Schneidawind, In-Suk Kim, Jesús Duque-Afonso, Stephen Hon Kit Wong, Masayuki Iwasaki, Erin H. Breese, James L. Zehnder, Matthew Porteus, Michael L. Cleary
Publikováno v:
Blood Advances, Vol 2, Iss 8, Pp 832-845 (2018)
Abstract: Genome editing provides a potential approach to model de novo leukemogenesis in primary human hematopoietic stem and progenitor cells (HSPCs) through induction of chromosomal translocations by targeted DNA double-strand breaks. However, ver
Externí odkaz:
https://doaj.org/article/fd68330af4e74c4ca8fe1fad62b29ab2
Autor:
Laura Crisafulli, Sharon Muggeo, Paolo Uva, Yulei Wang, Masayuki Iwasaki, Silvia Locatelli, Achille Anselmo, Federico S. Colombo, Carmelo Carlo-Stella, Michael L. Cleary, Anna Villa, Bernhard Gentner, Francesca Ficara
Publikováno v:
Haematologica, Vol 104, Iss 9 (2019)
The balance between self-renewal and differentiation is crucial to ensure the homeostasis of the hematopoietic system, and is a hallmark of hematopoietic stem cells. However, the underlying molecular pathways, including the role of micro-RNA, are not
Externí odkaz:
https://doaj.org/article/c4a1845919864bcd9ff2d2e828f0e774
Autor:
Feng Pan, Masayuki Iwasaki, Wenqi Wu, Yanan Jiang, Xin Yang, Li Zhu, Zhigang Zhao, Michael L Cleary
Publikováno v:
Blood Advances.
Acute myeloid leukemia (AML) with MLL gene rearrangement (MLLr) comprises a cellular hierarchy in which a subpopulation of cells serves as functional leukemia stem cells (LSCs). They are maintained by a unique gene expression program and chromatin st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44e845f42e4fafce0f005306b519a0d9
https://doi.org/10.1182/bloodadvances.2022008787
https://doi.org/10.1182/bloodadvances.2022008787
Autor:
Miho Koizumi, Hikaru Eto, Mai Saeki, Masahide Seki, Tsuyoshi Fukushima, Shoichiro Mukai, Hisamitsu Ide, Yasuyuki Sera, Masayuki Iwasaki, Yutaka Suzuki, Atsushi Tohei, Yusuke Kishi, Hiroaki Honda
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 36(12)
Recent studies have demonstrated that epigenetic modifications are deeply involved in neurogenesis; however, the precise mechanisms remain largely unknown. To determine the role of UTX (also known as KDM6A), a demethylase of histone H3K27, in neural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0803febfe3c3b716b985f1df18cc66d
https://pubmed.ncbi.nlm.nih.gov/36607616
https://pubmed.ncbi.nlm.nih.gov/36607616
Autor:
Keiyo Takubo, Phyo Wai Htun, Takeshi Ueda, Yasuyuki Sera, Masayuki Iwasaki, Miho Koizumi, Kohei Shiroshita, Hiroshi Kobayashi, Miho Haraguchi, Shintaro Watanuki, Zen-ichiro Honda, Norimasa Yamasaki, Ayako Nakamura-Ishizu, Fumio Arai, Noboru Motoyama, Tomohisa Hatta, Tohru Natsume, Toshio Suda, Hiroaki Honda
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 8/8/2023, Vol. 120 Issue 32, p1-10, 39p
Publikováno v:
Organic Letters. 22:7343-7347
Iron-catalyzed alkylative cyclization of alkenes bearing oxygen nucleophiles with secondary and tertiary alkyl bromides through carbon-carbon and carbon-oxygen bond formations has been developed. A broad substrate scope is an attractive feature of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc8e8b1870610341de3d14e2ac19e04
https://doi.org/10.1021/acs.orglett.0c02671
https://doi.org/10.1021/acs.orglett.0c02671
Autor:
Michael L. Cleary, Ravindra Majeti, Toshinobu Nishimura, Masayuki Iwasaki, Mahito Nakanishi, Brandon Saavedra, Yusuke Takahashi, Haojun Xu, Akira Shibuya, Fabian P. Suchy, Manami Ohtaka, Hiromitsu Nakauchi, Renata M. Martin, Shinichiro Monobe, Daiki Karigane, Scott R. Burrows
Publikováno v:
Gene Therapy. 27:525-534
Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have promising potential for opening new avenues in regenerative medicine. However, since the tumorigenic potential of undifferentiated pluripotent stem cells (PSCs) is a major sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d39647f614defaddfa848b60cc1b6561
https://doi.org/10.1038/s41434-020-0179-z
https://doi.org/10.1038/s41434-020-0179-z
Autor:
Masayuki Iwasaki, Hiroshi Toyota
Publikováno v:
IEEJ Transactions on Sensors and Micromachines. 140:60-64
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8afee6097750881b128aec71246b90bc
https://doi.org/10.1541/ieejsmas.140.60
https://doi.org/10.1541/ieejsmas.140.60
Autor:
Kiyohiko Nakajima, Masayuki Iwasaki, Yuta Sawanaka, Tomoya Fujii, Yasushi Nishihara, Takaaki Shinozaki, Song Zou, Kosei Nonaka
Publikováno v:
The Journal of Organic Chemistry. 84:15373-15379
Copper-catalyzed regioselective aminothiolation of terminal and internal alkenes with N-fluorobenzenesulfonimide and thiols has been developed. The three-component reaction is promoted by the addition of dimethyl sulfide. In addition to aromatic alke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a61f390ff90495e17ec9dd70674cff1
https://doi.org/10.1021/acs.joc.9b02392
https://doi.org/10.1021/acs.joc.9b02392