Zobrazeno 1 - 10
of 334
pro vyhledávání: '"Masayoshi Soma"'
Autor:
Keiichi Iwaya, Hisae Arai, Nanao Takatou, Yuka Morita, Rinko Ozeki, Hirofumi Nakaoka, Masaru Sakamoto, Tsutomu Kouno, Masayoshi Soma
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0266947 (2022)
Formalin-fixed paraffin-embedded (FFPE) blocks are used as biomaterials for next-generation sequencing of cancer panels. Cross-contamination is detected in approximately 5% of the DNA extracted from FFPE samples, which reduces the detection rate of g
Externí odkaz:
https://doaj.org/article/ea976aafb6274818bff91ffbbc5c9065
Autor:
Maki Kitai, Noboru Fukuda, Takahiro Ueno, Morito Endo, Takashi Maruyama, Masanori Abe, Kazuyoshi Okada, Masayoshi Soma, Koichi Matsumoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 134, Iss 1, Pp 29-36 (2017)
The Fc receptors (FcR) have pivotal roles in the pathogenesis of the autoimmune glomerulonephritis. We therefore investigated the effects of a Syk inhibitor on the progression of lupus nephritis and SH3 domain binding protein 2 and p38MAP kinase sign
Externí odkaz:
https://doaj.org/article/fa7cb2e074284727a54160abe18929c0
Autor:
Keiko Takagi, Yutaka Midorikawa, Tadatoshi Takayama, Hayato Abe, Kyoko Fujiwara, Masayoshi Soma, Hiroki Nagase, Toshio Miki, Noboru Fukuda
Publikováno v:
Molecules, Vol 25, Iss 12, p 2883 (2020)
Synthetic pyrrole-imidazole (PI) polyamides bind to the minor groove of double-helical DNA with high affinity and specificity, and inhibit the transcription of corresponding genes. In liver cancer, transforming growth factor (TGF)-β expression is co
Externí odkaz:
https://doaj.org/article/e3713efcbc7244cea8657eebc244860e
Autor:
Masashi Taniguchi, Kyoko Fujiwara, Yuji Nakai, Toshinori Ozaki, Nobuko Koshikawa, Kojima Toshio, Motoaki Kataba, Asako Oguni, Hiroyuki Matsuda, Yukihiro Yoshida, Yasuaki Tokuhashi, Noboru Fukuda, Takahiro Ueno, Masayoshi Soma, Hiroki Nagase
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 328-334 (2014)
Gene amplification and/or overexpression of the transcription factor c-MYC, which binds to the E-box sequence (5′-CACGTG-3′), has been observed in many human tumors. In this study, we have designed 5 pyrrole–imidazole (PI) polyamides recognizin
Externí odkaz:
https://doaj.org/article/72b591c7377049c69ef82b9190acfce0
Autor:
Kimitoshi Kato, Yukimoto Ishii, Takerou Mazaki, Toshiki Uehara, Hitomoi Nakamura, Hiroshi Kikuchi, Hiroaki Yamagami, Hideki Sato, Shigeaki Mizuno, Masayoshi Soma, Akihiro Henmi, Hideki Masuda, Mitsuhiko Moriyama, Masanori Tanaka
Publikováno v:
Case Reports in Gastroenterology, Vol 7, Iss 1, Pp 140-146 (2013)
The etiology of Cronkhite-Canada syndrome (CCS) remains unknown and many cases are refractory to treatment. Therefore, new therapies are urgently needed. Furthermore, a number of CCS cases with gastrointestinal carcinoma have been reported. Our patie
Externí odkaz:
https://doaj.org/article/d5e86820c62c4b3d97c49cae1cfb1eec
Autor:
Masanori Abe, Kazuyoshi Okada, Noriaki Maruyama, Hiroyuki Takashima, Osamu Oikawa, Masayoshi Soma
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
This study investigated differences between the clinical trajectories of diabetic nephropathy and nephrosclerosis using the Kidney Disease: Improving Global Outcomes (KDIGO) heat map and the clinical characteristics between the two diseases at RRT in
Externí odkaz:
https://doaj.org/article/e3d7df619279484eb9c84e7bff1b1903
Autor:
Kiyozumi Suzuki, Mitsuru Yanai, Yuta Hayashi, Hiromasa Otsuka, Kimitoshi Kato, Masayoshi Soma
Publikováno v:
IDCases, Vol 9, Iss C, Pp 12-13 (2017)
Externí odkaz:
https://doaj.org/article/18c07191280344d59bc734a7f1806592
Autor:
Jun Igarashi, Noboru Fukuda, Takashi Inoue, Shigeki Nakai, Kosuke Saito, Kyoko Fujiwara, Hiroyuki Matsuda, Takahiro Ueno, Yoshiaki Matsumoto, Takayoshi Watanabe, Hiroki Nagase, Toshikazu Bando, Hiroshi Sugiyama, Toshio Itoh, Masayoshi Soma
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125295 (2015)
We report a preclinical study of a pyrrole-imidazole (PI) polyamide that targets the human transforming growth factor (hTGF)-β1 gene as a novel transcriptional gene silencer in a common marmoset primate model. We designed and then synthesized PI pol
Externí odkaz:
https://doaj.org/article/ce90953aca344ff1b26df51c2f400988
Autor:
Masanori Abe, Noriaki Maruyama, Shiro Matsumoto, Kazuyoshi Okada, Takayuki Fujita, Koichi Matsumoto, Masayoshi Soma
Publikováno v:
International Journal of Nephrology, Vol 2011 (2011)
We conducted a prospective, randomized study to compare conventional continuous venovenous hemodiafiltration (CVVHDF) with sustained hemodiafiltration (SHDF) using an acetate-free dialysate. Fifty critically ill patients with acute kidney injury (AKI
Externí odkaz:
https://doaj.org/article/36bc17b2abbb485ebf42da84bc3a1993
Autor:
Katsuhiko Ogawa, Takayoshi Akimoto, Makoto Hara, Midori Fujishiro, Yutaka Suzuki, Masayoshi Soma, Hideto Nakajima
Publikováno v:
Journal of Nihon University Medical Association. 80:303-310
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8be640cbe770f35952e53edf2fba1f9
https://doi.org/10.4264/numa.80.6_303
https://doi.org/10.4264/numa.80.6_303