Výsledky vyhledávání - "Masayoshi Shirakawa"

Akademický článek

A phase 3, randomized, double-blind, clinical study to evaluate the long-term safety and efficacy of gefapixant in Japanese adult participants with refractory or unexplained chronic cough

Autor: Akio Niimi, Hironori Sagara, Masashi Kikuchi, Ichiro Arano, Asako Sato, Masayoshi Shirakawa, Carmen La Rosa, David Muccino

Publikováno v: Allergology International, Vol 71, Iss 4, Pp 498-504 (2022)

Background: In two phase 3, global clinical trials (COUGH-1 and COUGH-2), the P2X3-receptor antagonist gefapixant significantly reduced objective 24-h cough frequency in participants with refractory or unexplained chronic cough (RCC or UCC) at a dosa

Externí odkaz: https://doaj.org/article/625277a2bda64d69a3e9d1d3b31aee25

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Akademický článek

Safety and immunogenicity of a 15-valent pneumococcal conjugate vaccine in Japanese healthy infants: A Phase I study (V114-028)

Autor: Yasunori Ishihara, Haruo Kuroki, Hidenobu Hidaka, Kazuyuki Iwai, Keiko Wan, Masayoshi Shirakawa, Miyuki Sawata

Publikováno v: Human Vaccines & Immunotherapeutics, Vol 19, Iss 1 (2023)

This Phase I study evaluated the safety, tolerability, and immunogenicity of V114, a 15-valent pneumococcal conjugate vaccine (PCV), via subcutaneous (SC) or intramuscular (IM) administration, in healthy Japanese infants 3 months of age. A total of 1

Externí odkaz: https://doaj.org/article/bd2f6571c8134d74b33d486dc8c24bf6

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Akademický článek

The Bioequivalence and Effect of Food on the Pharmacokinetics of a Fixed‐Dose Combination Tablet Containing Rosuvastatin and Ezetimibe in Healthy Japanese Subjects

Autor: Chisato Nishida, Yuki Matsumoto, Katsukuni Fujimoto, Masayoshi Shirakawa, Rebecca Ellen Wrishko, Martin Otto Behm, Kenichi Furihata

Publikováno v: Clinical and Translational Science, Vol 12, Iss 6, Pp 704-712 (2019)

Certain patient populations are unable to achieve the recommended low‐density lipoprotein cholesterol goals with statin monotherapy alone. Such patients may benefit from concomitant therapy with ezetimibe (EZE) 10 mg added on to a statin. To this e

Externí odkaz: https://doaj.org/article/89b029df548640068e007a2561c257cc

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Akademický článek

Post-hoc analysis of injection-site reactions following vaccination with quadrivalent human papillomavirus vaccine in Japanese female clinical trial participants

Autor: Shinya Murata, Masayoshi Shirakawa, Yoshie Sugawara, Michiko Shuto, Miyuki Sawata, Yoshiyuki Tanaka

Publikováno v: Papillomavirus Research, Vol 10, Iss , Pp 100205- (2020)

Aim: The quadrivalent human papillomavirus (4vHPV) vaccine has demonstrated efficacy and immunogenicity and was generally well tolerated in clinical trials conducted in Japan. We report a detailed safety analysis of injection-site reactions in female

Externí odkaz: https://doaj.org/article/6e1ebb7f9cb44358a0f1f979375ab686

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Safety and Immunogenicity of V114, a 15-valent Pneumococcal Conjugate Vaccine, Compared with 13-valent Pneumococcal Conjugate Vaccine in Japanese Adults Aged ≥65 Years: Subgroup Analysis of a Randomized Phase III Trial (PNEU-AGE)

Autor: Hiroyuki Kishino, Miyuki Sawata, Rie Igarashi, Masayoshi Shirakawa, Alison Pedley, Luwy Musey, Heather Loryn Platt, Ulrike Kirsten Buchwald

Publikováno v: Japanese journal of infectious diseases. 75(6)

The safety and immunogenicity of V114, a 15-valent pneumococcal conjugate vaccine (PCV), were assessed in a pivotal phase III trial conducted in healthy adults ≥50 years of age (NCT03950622, Japic-CTI 194845). We performed a subgroup analysis of 24

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc60f0499869003f18ae5c871e06c2c
https://pubmed.ncbi.nlm.nih.gov/35908869

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A randomized, placebo‐controlled trial to assess the efficacy and safety of sitagliptin in J apanese patients with type 2 diabetes and inadequate glycaemic control on ipragliflozin

Autor: Asako Sato, Keith D. Kaufman, Yutaka Seino, Masayoshi Shirakawa, Samuel S. Engel, Taro Okamoto, Kohei Kaku, Edward A. O'Neill, Takashi Kadowaki

Publikováno v: Diabetes, Obesity & Metabolism

Aims To investigate the efficacy, safety and tolerability of sitagliptin 50 mg once daily added to ipragliflozin 50 mg once daily monotherapy in Japanese patients with type 2 diabetes (T2D). Materials and Methods Japanese patients with T2D and glycat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac6a5a6c979367fba4abd236fdfdcc2
https://doi.org/10.1111/dom.14346

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The safety and efficacy of relebactam/imipenem/cilastatin in Japanese patients with complicated intra-abdominal infection or complicated urinary tract infection: A multicenter, open-label, noncomparative phase 3 study

Autor: Amanda Paschke, Norihiro Aoyama, Fumihiko Yoneyama, Shigeru Kohno, Hiroaki Kikukawa, Hiroyuki Bando, Masayoshi Shirakawa, Kazuya Kawahara, Akiko Takase, Michelle L Brown

Publikováno v: Journal of Infection and Chemotherapy. 27:262-270

Introduction Relebactam, a novel class A/C β-lactamase inhibitor developed as a fixed-dose combination with imipenem/cilastatin, restores imipenem activity against imipenem-nonsusceptible gram-negative pathogens. Methods This phase 3, multicenter, o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32be5563469cc67e6cbb9802abceadcd
https://doi.org/10.1016/j.jiac.2020.09.032

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The Bioequivalence and Effect of Food on the Pharmacokinetics of a Fixed‐Dose Combination Tablet Containing Rosuvastatin and Ezetimibe in Healthy Japanese Subjects

Autor: Katsukuni Fujimoto, Rebecca E Wrishko, Yuki Matsumoto, Martin O. Behm, Chisato Nishida, Kenichi Furihata, Masayoshi Shirakawa

Publikováno v: Clinical and Translational Science
Clinical and Translational Science, Vol 12, Iss 6, Pp 704-712 (2019)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d95f80aa162b50452459c50d764779f
https://doi.org/10.1111/cts.12677

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Efficacy and safety of ipragliflozin in Japanese patients with type 2 diabetes and inadequate glycaemic control on sitagliptin

Autor: Asako Sato, Keith D. Kaufman, Yutaka Seino, Samuel S. Engel, Kohei Kaku, Taro Okamoto, Edward A. O'Neill, Masayoshi Shirakawa, Takashi Kadowaki

Publikováno v: Diabetes, Obesity & Metabolism

Aims To assess the efficacy, safety and tolerability of ipragliflozin 50 mg once daily added to sitagliptin 50 mg once daily monotherapy in Japanese patients with type 2 diabetes (T2D). Materials and Methods The results of two clinical trials are rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8975415647305cd1fd4eaffde820fe74
https://pubmed.ncbi.nlm.nih.gov/34033212

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Post-hoc analysis of injection-site reactions following vaccination with quadrivalent human papillomavirus vaccine in Japanese female clinical trial participants

Autor: Masayoshi Shirakawa, Michiko Shuto, Shinya Murata, Miyuki Sawata, Yoshie Sugawara, Yoshiyuki Tanaka

Publikováno v: Papillomavirus Research, Vol 10, Iss, Pp 100205-(2020)
Papillomavirus Research

Aim The quadrivalent human papillomavirus (4vHPV) vaccine has demonstrated efficacy and immunogenicity and was generally well tolerated in clinical trials conducted in Japan. We report a detailed safety analysis of injection-site reactions in female

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126fc34f1ac133d8732497f098e8f698
http://www.sciencedirect.com/science/article/pii/S2405852120300045

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