Výsledky vyhledávání - "Masayoshi Oh-eda"

Crystal structure of human factor VIIa/tissue factor in complex with peptide mimetic inhibitor

Autor: Masateru Ohta, Yoshiaki Watanabe, Hirofumi Kodama, Toshiro Kozono, Takuya Shiraishi, Susumu Itoh, Haruhiko Sato, Takaki Koga, Masayuki Haramura, Yasufumi Kikuchi, Kunihiro Hattori, Akihisa Sakamoto, Naohiro Yabuta, Toru Esaki, Masayoshi Oh-eda, Shojiro Kadono

Publikováno v: Biochemical and Biophysical Research Communications. 324:1227-1233

The 3D structure of human factor VIIa/soluble tissue factor in complex with a peptide mimetic inhibitor, propylsulfonamide-D-Thr-Met-p-aminobenzamidine, is determined by X-ray crystallography. As compared with the interactions between thrombin and th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e64d66cd4fa9c3521e5edf275db3e34
https://doi.org/10.1016/j.bbrc.2004.09.182

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Carbohydrate structure and differential binding of prostate specific antigen to Maackia amurensis lectin between prostate cancer and benign prostate hypertrophy

Autor: Minoru Fukuda, Yoichi Arai, Chikara Ohyama, Masahiro Hosono, Kazuo Nitta, Kazuyuki Yoshikawa, Masayoshi Oh-eda, Tomonori Habuchi

Publikováno v: Glycobiology. 14:671-679

Serum prostate-specific antigen (PSA) assay is widely used for detection of prostate cancer. Because PSA is also synthesized from normal prostate, false positive diagnosis cannot be avoided by the conventional serum PSA test. To apply the cancer-asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7042a62ebed109633ed92cabd0be3131
https://doi.org/10.1093/glycob/cwh071

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A bivalent single-chain Fv fragment against CD47 induces apoptosis for leukemic cells

Autor: Shin-ichiro Iida, Masayoshi Oh-eda, Koji Otabe, Yasufumi Kikuchi, Naoshi Fukushima, Masayuki Tsuchiya, Shinsuke Uno, Yasushi Yoshimura

Publikováno v: Biochemical and Biophysical Research Communications. 315:912-918

We constructed a single-chain antibody fragment (scFv) of murine monoclonal antibody, MABL, which specifically bound to human CD47 (hCD47) and induced apoptosis of the leukemic cells. The scFv of MABL antibody with a 15-residue linker (MABL scFv-15)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46908ebafc94b5eb8f6c7e258d376161
https://doi.org/10.1016/j.bbrc.2004.01.128

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High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis

Autor: Ikumi Matsushita, Masayoshi Oh-eda, Kanji Uchida, Naoto Keicho, Koh Nakata, Kazuo Hanaoka, Yoshitsugu Yamada, Emi Hamano, Yoshinobu Eishi, Ikuo Ishige, Ayako Mikami, John F. Seymour, Bruce C. Trapnell, Takahiro Terakawa, Takayuki Kitamura

Publikováno v: Blood. 103:1089-1098

Deficiency of granulocyte-macrophage colony-stimulating factor (GM-CSF) in mice results in pulmonary alveolar proteinosis (PAP) from impaired surfactant catabolism by alveolar macrophages (AMs). Recently, we have shown that neutralizing anti-GM-CSF a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764ecfe15ca73a89c1f6fc8196162b8b
https://doi.org/10.1182/blood-2003-05-1565

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Actinohivin, a Novel Anti-HIV Protein from an Actinomycete That Inhibits Syncytium Formation: Isolation, Characterization, and Biological Activities

Autor: Mayumi Shinose, Hideki Nakashima, Haruo Tanaka, Keiichi Matsuzaki, Megumi Okamoto, Kiyohisa Mizumoto, Masayoshi Oh-eda, Junji Inokoshi, Satoshi Asanuma, Kazunobu Fujita, Harumi Chiba, Satoshi Ōmura, Minako Iwama, Yoko Takahashi

Publikováno v: Biochemical and Biophysical Research Communications. 282:595-601

Blocking human immunodeficiency virus (HIV) entry into target cells is an important goal of HIV and acquired immune deficiency syndrome (AIDS) therapies. We have searched for anti-HIV substances from microorganisms using a syncytium formation assay s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea5fee69b1a4bc9b37af392ba09304f
https://doi.org/10.1006/bbrc.2001.4495

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[Untitled]

Autor: S. Hakomori, Tetsu Matsuura, Masayoshi Oh-eda, Makoto Satoh, Fatemeh Moosavi Nejad, Takemi Enomoto, Seiichi Saito, Takashi Masuko, Seiichi Orikasa, Akihiro Ito

Publikováno v: Glycoconjugate Journal. 18:475-485

Renal cell carcinoma (RCC) has been characterized by high expression of three types of disialogangliosides: two based on lacto-series type 1 structure (disialosyl Lc4, GalNAc disialosyl Lc4), the other based on globo-series structure (disialosyl glob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d02040fba87d6fd30ae867f33fd8b976
https://doi.org/10.1023/a:1016281002344

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Alpha-Mannosidase-II Deficiency Results in Dyserythropoiesis and Unveils an Alternate Pathway in Oligosaccharide Biosynthesis

Autor: Yung-Feng Liao, Kurt W. Marek, K. Panneerselvam, Jamey D. Marth, Michiko N. Fukuda, Hudson H. Freeze, Masayoshi Oh-Eda, Anita Lal, Kelley W. Moremen, Daniel Chui

Publikováno v: Cell. 90:157-167

Alpha-mannosidase-II (alphaM-II) catalyzes the first committed step in the biosynthesis of complex asparagine-linked (N-linked) oligosaccharides (N-glycans). Genetic deficiency of alphaM-II should abolish complex N-glycan production as reportedly doe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7733878255cac2cf373c793c72eca9
https://doi.org/10.1016/s0092-8674(00)80322-0

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Polypeptide and Carbohydrate Structure of Recombinant Human Interleukin-6 Produced in Chinese Hamster Ovary Cells

Autor: Keiko Esaki, Masakazu Hasegawa, Hitoshi Kuboniwa, Tetsuro Orita, Masayoshi Oh-eda, Norimichi Ochi

Publikováno v: The Journal of Biochemistry. 115:345-350

A glycosylated form of human interleukin 6 (hIL-6) has been produced in Chinese hamster ovary (CHO) cells transfected with a cDNA clone for human IL-6. Recombinant hIL-6 was purified from a culture supernatant of the transfected CHO cells, and used f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b03ec582d4f07c4d5fb0665f42620d
https://doi.org/10.1093/oxfordjournals.jbchem.a124340

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Reduction of the leukemogenic potential of malignant murine leukemic cells by in vivo treatment with recombinant human granulocyte colony-stimulating factor

Autor: Tetsuro Orita, Masayoshi Ono, Masakazu Hasegawa, Taira Maekawa, Masahiko Tamura, Hitoshi Nomura, Masayoshi Oh-eda, Tatsuo Abe

Publikováno v: Leukemia Research. 17:593-600

We have investigated the effect of recombinant human granulocyte colony-stimulating factor (rhG-CSF) administration on the leukemogenic potential of L-103 murine leukemic cells. Leukemogenic potential was assessed by comparing the regression lines dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8044ec03c11149ef6c725025da1501ff
https://doi.org/10.1016/0145-2126(93)90090-8

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O-linked sugar chain of human granulocyte colony-stimulating factor protects it against polymerization and denaturation allowing it to retain its biological activity

Autor: Masakazu Hasegawa, Norimichi Ochi, K Tomonou, Tetsuro Orita, Hitoshi Kuboniwa, Masayoshi Oh-eda, Tetsuo Kojima, Kunihiro Hattori, T Yamazaki

Publikováno v: Journal of Biological Chemistry. 265:11432-11435

Human granulocyte colony-stimulating factor (hG-CSF) is a glycoprotein carrying one O-linked sugar chain. To clarify the role of the oligosaccharide in hG-CSF, some biological and physicochemical properties of the deglycosylated hG-CSF and the intact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0289daf7162f55d008b50bb099d99edb
https://doi.org/10.1016/s0021-9258(19)38416-9

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