Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Masayoshi, Suda"'
Autor:
Yohko Yoshida, Ippei Shimizu, Atsuhiro Shimada, Keita Nakahara, Sachiko Yanagisawa, Minoru Kubo, Shinji Fukuda, Chiharu Ishii, Hiromitsu Yamamoto, Takamasa Ishikawa, Kuniyuki Kano, Junken Aoki, Goro Katsuumi, Masayoshi Suda, Kazuyuki Ozaki, Yutaka Yoshida, Shujiro Okuda, Shigeo Ohta, Shiki Okamoto, Yasuhiko Minokoshi, Kanako Oda, Toshikuni Sasaoka, Manabu Abe, Kenji Sakimura, Yoshiaki Kubota, Norihiko Yoshimura, Shingo Kajimura, Maria Zuriaga, Kenneth Walsh, Tomoyoshi Soga, Tohru Minamino
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Low body temperature predicts a poor outcome in patients with heart failure, but the underlying pathological mechanisms and implications are largely unknown. Brown adipose tissue (BAT) was initially characterised as a thermogenic organ, and
Externí odkaz:
https://doaj.org/article/47e7cf28377a4d3a94aefb37d6721e18
Autor:
Masayoshi Suda, Ippei Shimizu, Goro Katsuumi, Chieh Lun Hsiao, Yohko Yoshida, Naomi Matsumoto, Yutaka Yoshida, Akihiro Katayama, Jun Wada, Masahide Seki, Yutaka Suzuki, Shujiro Okuda, Kazuyuki Ozaki, Mayumi Nakanishi-Matsui, Tohru Minamino
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Accumulation of senescent cells in various tissues has been reported to have a pathological role in age-associated diseases. Elimination of senescent cells (senolysis) was recently reported to reversibly improve pathological aging phenotypes
Externí odkaz:
https://doaj.org/article/634d9e24557b4a668bdb989244cc9644
Autor:
Masaaki Nakao, Ippei Shimizu, Goro Katsuumi, Yohko Yoshida, Masayoshi Suda, Yuka Hayashi, Ryutaro Ikegami, Yung Ting Hsiao, Shujiro Okuda, Tomoyoshi Soga, Tohru Minamino
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Patients with type 2 diabetes treated with Sodium glucose transporter 2 (SGLT2) inhibitors show reduced mortality and hospitalization for heart failure (HF). SGLT2 inhibitors are considered to activate multiple cardioprotective pathways; how
Externí odkaz:
https://doaj.org/article/d12309a66d7741a1b29740eef4e5bfd0
Endothelial SIRT-1 has a critical role in the maintenance of capillarization in brown adipose tissue
Autor:
Ryo Furuuchi, Ippei Shimizu, Yohko Yoshida, Goro Katsuumi, Masayoshi Suda, Yoshiaki Kubota, Kenneth Walsh, Tohru Minamino
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105424- (2022)
Summary: Brown adipose tissue (BAT) has critical roles in thermogenesis and systemic metabolism. Capillary rarefaction was reported to develop in BAT with dietary obesity, and previous studies showed that suppression of vascular endothelial growth fa
Externí odkaz:
https://doaj.org/article/d2b65e57f6684cdfa97380fb8c4de74d
Autor:
Yung Ting Hsiao, Ippei Shimizu, Takayuki Wakasugi, Yohko Yoshida, Ryutaro Ikegami, Yuka Hayashi, Masayoshi Suda, Goro Katsuumi, Masaaki Nakao, Takuya Ozawa, Daisuke Izumi, Takeshi Kashimura, Kazuyuki Ozaki, Tomoyoshi Soga, Tohru Minamino
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Prognosis of severe heart failure remains poor. Urgent new therapies are required. Some heart failure patients do not respond to established multidisciplinary treatment and are classified as “non-responders”. The outcome is especially po
Externí odkaz:
https://doaj.org/article/6b102410e463408695d87fe8621b2bd0
Autor:
Masayoshi Suda, Karl H. Paul, Tohru Minamino, Jordan D. Miller, Amir Lerman, Georgina M. Ellison-Hughes, Tamar Tchkonia, James L. Kirkland
Publikováno v:
Cells, Vol 12, Iss 9, p 1296 (2023)
Senescent cell accumulation has been observed in age-associated diseases including cardiovascular diseases. Senescent cells lack proliferative capacity and secrete senescence-associated secretory phenotype (SASP) factors that may cause or worsen many
Externí odkaz:
https://doaj.org/article/60205bf4c27a4be98e6b5b48c2e00034
Autor:
Yohko Yoshida, Ippei Shimizu, Yung-Ting Hsiao, Masayoshi Suda, Goro Katsuumi, Masahide Seki, Yutaka Suzuki, Shujiro Okuda, Tomoyoshi Soga, Tohru Minamino
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104268- (2022)
Summary: Brown adipose tissue (BAT) is a metabolically active organ that contributes to the thermogenic response to cold exposure. In addition, other thermogenic cells termed beige adipocytes are generated in white adipose tissue (WAT) by cold exposu
Externí odkaz:
https://doaj.org/article/ef1b78d1f4ea4df98fc4bc2211f8220c
Autor:
Takayuki Wakasugi, Ippei Shimizu, Yohko Yoshida, Yuka Hayashi, Ryutaro Ikegami, Masayoshi Suda, Goro Katsuumi, Masaaki Nakao, Makoto Hoyano, Takeshi Kashimura, Kazufumi Nakamura, Hiroshi Ito, Takashi Nojiri, Tomoyoshi Soga, Tohru Minamino
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212889 (2019)
Pulmonary arterial hypertension (PAH) is characterized by remodeling and narrowing of the pulmonary arteries, which lead to elevation of right ventricular pressure, heart failure, and death. Proliferation of pulmonary artery smooth muscle cells (PASM
Externí odkaz:
https://doaj.org/article/cc64bc7f4b9b4a72a39813f5ff8a2149
Autor:
Masayoshi Suda, Ippei Shimizu, Goro Katsuumi, Yohko Yoshida, Yuka Hayashi, Ryutaro Ikegami, Naomi Matsumoto, Yutaka Yoshida, Ryuta Mikawa, Akihiro Katayama, Jun Wada, Masahide Seki, Yutaka Suzuki, Atsushi Iwama, Hironori Nakagami, Ayako Nagasawa, Ryuichi Morishita, Masataka Sugimoto, Shujiro Okuda, Masanori Tsuchida, Kazuyuki Ozaki, Mayumi Nakanishi-Matsui, Tohru Minamino
Publikováno v:
Nature Aging. 1:1117-1126
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2654f205229cdae5c842e004ff122047
https://doi.org/10.1038/s43587-021-00151-2
https://doi.org/10.1038/s43587-021-00151-2
Autor:
Ryutaro Ikegami, Ippei Shimizu, Takeshi Sato, Yohko Yoshida, Yuka Hayashi, Masayoshi Suda, Goro Katsuumi, Ji Li, Takayuki Wakasugi, Yasuhiko Minokoshi, Shiki Okamoto, Eiichi Hinoi, Søren Nielsen, Naja Zenius Jespersen, Camilla Scheele, Tomoyoshi Soga, Tohru Minamino
Publikováno v:
Cell Reports, Vol 24, Iss 11, Pp 2827-2837.e5 (2018)
Summary: Brown adipose tissue (BAT) is a metabolically active organ that contributes to the maintenance of systemic metabolism. The sympathetic nervous system plays important roles in the homeostasis of BAT and promotes its browning and activation. H
Externí odkaz:
https://doaj.org/article/4f53263889c44265b7fe4c96e644b256