Functional Characterization of the mazEF Toxin-Antitoxin System in the Pathogenic Bacterium Agrobacterium tumefaciens

Autor: Wonho Choi, Yoshihiro Yamaguchi, Ji-Young Park, Sang-Hyun Park, Hyeok-Won Lee, Byung-Kwan Lim, Michael Otto, Masayori Inouye, Min-Ho Yoon, Jung-Ho Park

Publikováno v: Microorganisms, Vol 9, Iss 5, p 1107 (2021)

Agrobacterium tumefaciens is a pathogen of various plants which transfers its own DNA (T-DNA) to the host plants. It is used for producing genetically modified plants with this ability. To control T-DNA transfer to the right place, toxin-antitoxin (T

Externí odkaz: https://doaj.org/article/a4628961f1c741e4a2ace5f23a94d26d

Identification of the first functional toxin-antitoxin system in Streptomyces.

Autor: Laura Sevillano, Margarita Díaz, Yoshihiro Yamaguchi, Masayori Inouye, Ramón I Santamaría

Publikováno v: PLoS ONE, Vol 7, Iss 3, p e32977 (2012)

Toxin-antitoxin (TA) systems are widespread among the plasmids and genomes of bacteria and archaea. This work reports the first description of a functional TA system in Streptomyces that is identical in two species routinely used in the laboratory: S

Externí odkaz: https://doaj.org/article/1d80b768a4e64b9c81352f1d9986ee93

A novel gyrase inhibitor from toxin-antitoxin system expressed by Staphylococcus aureus

Autor: Fuminori Kato, Yoshihiro Yamaguchi, Keiko Inouye, Koichi Matsuo, Yojiro Ishida, Masayori Inouye

Publikováno v: The FEBS journalReferences.

Toxin-antitoxin (TA) systems consist of a toxin inhibiting essential cellular functions (such as DNA, RNA and protein synthesis), and its cognate antitoxin neutralizing the toxicity. Recently, we identified a TA system termed TsbA/TsbT in the Staphyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0d72ce7fc56b20dd4e7729907350c0
https://pubmed.ncbi.nlm.nih.gov/36148483

Evolution of the genetic code; Evidence from serine codon use disparity in Escherichia coli

Autor: Masayori Inouye, Keiko Inouye, Yojiro Ishida, Risa Takino

Publikováno v: Proceedings of the National Academy of Sciences. 117:28572-28575

Among the 20 amino acids, three of them—leucine (Leu), arginine (Arg), and serine (Ser)—are encoded by six different codons. In comparison, all of the other 17 amino acids are encoded by either 4, 3, 2, or 1 codon. Peculiarly, Ser is separated in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b328e0776259c808c09ce64f6cd8fc38
https://doi.org/10.1073/pnas.2014567117

Assessment of prediction methods for protein structures determined by NMR in CASP14 : impact of AlphaFold2

Autor: Masayori Inouye, Swapna Gurla, Andriy Kryshtafovych, Gaohua Liu, Naohiro Kobayashi, Yojiro Ishida, Beate Bersch, Gaetano T. Montelione, Yutaka Kuroda, Yuanpeng J. Huang, Nan Wu, Ning Zhang, Krzysztof Fidelis, Toshio Yamazaki, Andy LiWang

Publikováno v: Proteins-Structure, Function and Bioinformatics
Proteins-Structure, Function and Bioinformatics, Wiley, In press, ⟨10.1002/prot.26246⟩
Proteins, vol 89, iss 12
Proteins-Structure, Function and Bioinformatics, In press, ⟨10.1002/prot.26246⟩

NMR studies can provide unique information about protein conformations in solution. In CASP14, three reference structures provided by solution NMR methods were available (T1027, T1029, and T1055), as well as a fourth data set of NMR-derived contacts

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090ed853abaf8daa5ef12173b5abb054
https://hal.archives-ouvertes.fr/hal-03357450/document