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What is the absolute configuration of (+)-crispatanolide isolated from Makinoa crispata (liverwort)?
Autor:
Motoo Tori, Masayo Kameoka, Akiyo Yamamoto, Minako Kumano, Reiko Mizutani, Katsuyuki Nakashima, Masakazu Sono, Hiroyuki Kawano, Hikari Kodama
Publikováno v:
Tetrahedron Letters. 56:4912-4915
Crispatanolide, which was isolated from Makinoa crispata (liverwort) in 1980, was synthesized in its chiral form starting from 3-substituted-2-bromocyclohex-2-en-1-one using CBS reduction. The absolute configuration was established using the modified