Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Masayo Yamagata"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 145, Iss 1, Pp 79-87 (2021)
In the present study, we investigated the renoprotective effects of long-term treatment with yohimbine, an α2-adrenoceptor inhibitor, in a 5/6 nephrectomy-induced chronic kidney disease (CKD) rat model. Male Sprague–Dawley rats were randomly alloc
Externí odkaz:
https://doaj.org/article/0cda791b2dab4694ae439c2af03835b5
Autor:
Takaomi Shimokawa, Hidenobu Tsutsui, Takeshi Miura, Masashi Takama, Kohei Hayashi, Toru Nishinaka, Tomoyuki Terada, Kozo Yoneda, Masayo Yamagata, Tokihito Yukimura
Publikováno v:
Journal of Pharmacological Sciences, Vol 139, Iss 3, Pp 137-142 (2019)
Ischemia/reperfusion injury is the most common cause of acute kidney injury. We previously revealed that pre-treatment with yohimbine or JP-1302 attenuated renal ischemia/reperfusion injury by inhibition of α2C-adrenoceptor antagonist. The aim of th
Externí odkaz:
https://doaj.org/article/128eb550d8d84b08829cfa8308a52125
Publikováno v:
Journal of Pharmacological Sciences, Vol 145, Iss 1, Pp 79-87 (2021)
In the present study, we investigated the renoprotective effects of long-term treatment with yohimbine, an α2-adrenoceptor inhibitor, in a 5/6 nephrectomy-induced chronic kidney disease (CKD) rat model. Male Sprague–Dawley rats were randomly alloc
Autor:
Tomoyuki Terada, Tokihito Yukimura, Toru Nishinaka, Masayo Yamagata, Kohei Hayashi, Hidenobu Tsutsui, Kozo Yoneda, Masashi Takama, Takeshi Miura, Takaomi Shimokawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 139, Iss 3, Pp 137-142 (2019)
Ischemia/reperfusion injury is the most common cause of acute kidney injury. We previously revealed that pre-treatment with yohimbine or JP-1302 attenuated renal ischemia/reperfusion injury by inhibition of α2C-adrenoceptor antagonist. The aim of th
Autor:
Masako Tanaka, Saya Mun, Akihito Harada, Yasuyuki Ohkawa, Azusa Inagaki, Soichi Sano, Katsuyuki Takahashi, Yasukatsu Izumi, Mayuko Osada-Oka, Hideki Wanibuchi, Masayo Yamagata, Tokihito Yukimura, Katsuyuki Miura, Masayuki Shiota, Hiroshi Iwao
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96785 (2014)
Heat shock cognate protein 70 (Hsc70) acts as a molecular chaperone for the maintenance of intracellular proteins, which allows cancer cells to survive under proteotoxic stress. We attempted to use Hsc70 to identify key molecules in cancer cell survi
Externí odkaz:
https://doaj.org/article/d800ac9edc8b48e4aceebccb74a4da87
Publikováno v:
Cell and tissue research. 387(2)
Renal α2-adrenoceptors have been reported to play a role in the regulation of urinary output, renin secretion, and water and sodium excretion in the kidneys. However, the distribution of α2-adrenoceptor subtypes in the kidneys remains unclear. In t
Publikováno v:
Journal of pharmacological sciences. 145(1)
In the present study, we investigated the renoprotective effects of long-term treatment with yohimbine, an α
Autor:
Masayo Yamagata, Masashi Takama, Takeshi Miura, Hidenobu Tsutsui, Takaomi Shimokawa, Tomoyuki Terada, Tokihito Yukimura, Toru Nishinaka
Publikováno v:
European Journal of Pharmacology. 838:113-119
Nephrotoxicity is a major adverse reaction of the anticancer drug, cisplatin. We investigated the renoprotective effects of the α2-adrenoceptor antagonist, yohimbine and selective α2C-adrenoceptor antagonist, JP-1302, in cisplatin-treated Sprague D
Autor:
Takeshi Miura, Hidenobu Tsutsui, Takao Tanba, Masayo Yamagata, Shuhei Yoshida, Tomoyuki Terada, Tokihito Yukimura, Takaomi Shimokawa, Ayumi Tojo, Masashi Takama, Toru Nishinaka
Publikováno v:
European Journal of Pharmacology. 781:36-44
Excitation of renal sympathetic nervous activity and the resulting increased levels of renal venous norepinephrine play important roles in renal ischaemia/reperfusion injury in rats. This study examined the effects of yohimbine, a non-selective α2-a
Publikováno v:
European Journal of Pharmacology. 871:172917
Sepsis-induced acute kidney injury (AKI) is frequently observed in the intensive care unit. We previously revealed that yohimbine, an α2-adrenoceptor antagonist, has protective effects on renal ischemia/reperfusion injury-induced AKI in rats. This s