Effect of storage conditions on salivary polyamines quantified via liquid chromatography-mass spectrometry

Autor: Atsumi Tomita, Masayo Mori, Kana Hiwatari, Eri Yamaguchi, Takao Itoi, Makoto Sunamura, Tomoyoshi Soga, Masaru Tomita, Masahiro Sugimoto

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)

Abstract Salivary polyamines are potential non-invasive tools for screening various types of cancers. For clinical use, the reproducibility of these metabolites should be evaluated under various storage conditions, including duration and temperature,

Externí odkaz: https://doaj.org/article/46ac416dfa974aa08de987c568a8b91c

Urinary Polyamine Biomarker Panels with Machine-Learning Differentiated Colorectal Cancers, Benign Disease, and Healthy Controls

Autor: Tetsushi Nakajima, Kenji Katsumata, Hiroshi Kuwabara, Ryoko Soya, Masanobu Enomoto, Tetsuo Ishizaki, Akihiko Tsuchida, Masayo Mori, Kana Hiwatari, Tomoyoshi Soga, Masaru Tomita, Masahiro Sugimoto

Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 3, p 756 (2018)

Colorectal cancer (CRC) is one of the most daunting diseases due to its increasing worldwide prevalence, which requires imperative development of minimally or non-invasive screening tests. Urinary polyamines have been reported as potential markers to

Externí odkaz: https://doaj.org/article/c006165d28324abe80b983a9e16e3038

Tyrosine hydroxylase conditional KO mice reveal peripheral tissue-dependent differences in dopamine biosynthetic pathways

Autor: Masayo Mori-Kojima, Chiaki Kawamoto, Satoshi Hara, Daniel Metzger, Katsuya Miyajima, Chiho Sumi-Ichinose, Tamae Ohye, Toshikuni Sasaoka, Hiroshi Ichinose, Nae Saito

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 296, pp.100544. ⟨10.1016/j.jbc.2021.100544⟩
The Journal of Biological Chemistry

Dopamine (DA) exerts well-known functions in the brain as a neurotransmitter. In addition, it plays important physiological roles in peripheral organs, but it is largely unknown how and where peripheral DA is synthesized and regulated. Catecholamines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc82740686aefef1da6e4fb1ac3ccb2
https://doi.org/10.1016/j.jbc.2021.100544

Early gestational maternal low-protein diet diminishes hepatic response to fasting in young adult male mice

Autor: Katsuko Sudo, Masaaki Muramatsu, Masayo Mori, Chihiro Imai, Masahiro Sugimoto, Noriko Sato

Publikováno v: Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)

Maternal low-protein (MLP) diet can lead to hepatic steatosis, which only develops with ageing. It is still unclear whether the young offspring show any signs of past exposure to prenatal adverse conditions. We hypothesized that early nutritional ins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee0e62a7306ac6948b649769894e4c3
http://europepmc.org/articles/PMC5575317

Human blood metabolite timetable indicates internal body time

Autor: Tomoyoshi Soga, Yoichi Minami, Ken-ichi Honma, Masayo Mori, Kazuo Mishima, Akiko Hida, Sato Honma, Hiroki R. Ueda, Masahiro Sugimoto, Takeya Kasukawa

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 109(37)

A convenient way to estimate internal body time (BT) is essential for chronotherapy and time-restricted feeding, both of which use body-time information to maximize potency and minimize toxicity during drug administration and feeding, respectively. P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb860af9ed47bf894ed48c89093c7d6f
https://pubmed.ncbi.nlm.nih.gov/22927403