Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Masayasu Kuwahara"'
Publikováno v:
Applied Sciences, Vol 10, Iss 23, p 8755 (2020)
We have previously developed a bifunctional aptamer (bApt) binding to both human thrombin and camptothecin derivative (CPT1), and showed that bApt acts as a drug carrier under the phenomenon named selective oligonucleotide entrapment in fibrin polyme
Externí odkaz:
https://doaj.org/article/7740d34eb7a1415a92b855b4aa0cfbed
Publikováno v:
Molecules, Vol 25, Iss 21, p 4936 (2020)
We previously synthesized thioflavin T (ThT) with a hydroxyethyl group introduced at the N3-position (ThT-HE), which binds predominantly to the parallel G-quadruplex (G4) structure found in c-Myc and emits strong fluorescence. In this study, to inves
Externí odkaz:
https://doaj.org/article/ecac17ff50cf4ddc85d5d6c219cf4d5d
Autor:
Naoki Sugimoto, Masayasu Kuwahara, Yuuya Kasahara, Shunsuke Kitadume, Hiroaki Ozaki, Yuri Imaizumi, Hiroto Fujita
Publikováno v:
Pharmaceuticals, Vol 6, Iss 9, Pp 1082-1093 (2013)
We recently selected DNA aptamers that bind to camptothecin (CPT) and CPT derivatives from a 70-mer oligodeoxyribonucleotide (ODN) library using the Systematic Evolution of Ligands by EXponential enrichment (SELEX) method. The target-binding activity
Externí odkaz:
https://doaj.org/article/923a849ab45d404fbd68132d7fec0d7c
Autor:
Satoshi Obika, Akio Sugiyama, Hiroaki Sawai, Hiroaki Ozaki, Yuuya Kasahara, Hiroki Nara, Yuuki Takano, Masayasu Kuwahara
Publikováno v:
Molecules, Vol 15, Iss 11, Pp 8229-8240 (2010)
Recently, KOD and its related DNA polymerases have been used for preparing various modified nucleic acids, including not only base-modified nucleic acids, but also sugar-modified ones, such as bridged/locked nucleic acid (BNA/LNA) which would be prom
Externí odkaz:
https://doaj.org/article/24b88a9c81bd4045bc043bae26c6518f
Autor:
Masayasu Kuwahara, Naoki Sugimoto
Publikováno v:
Molecules, Vol 15, Iss 8, Pp 5423-5444 (2010)
Nucleic acids are attractive materials for creating functional molecules that have applications as catalysts, specific binders, and molecular switches. Nucleic acids having such functions can be obtained by random screening, typically using in vitro
Externí odkaz:
https://doaj.org/article/fc0a44d7e8424d23aa0c4d3919c8fc58
Publikováno v:
Journal of Nucleic Acids, Vol 2013 (2013)
Externí odkaz:
https://doaj.org/article/e8df3f99bdf044c6b4b2a7567446a18d
Autor:
Yuuya Kasahara, Masayasu Kuwahara
Publikováno v:
Journal of Nucleic Acids, Vol 2012 (2012)
Specific binders comprised of nucleic acids, that is, RNA/DNA aptamers, are attractive functional biopolymers owing to their potential broad application in medicine, food hygiene, environmental analysis, and biological research. Despite the large num
Externí odkaz:
https://doaj.org/article/46003fd82c584d0c934489dd09ebe4ff
Autor:
Masayasu Kuwahara
Publikováno v:
Journal of Nihon University Medical Association. 79:379-382
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e27e97fa55bc20207f67a825b1c0954
https://doi.org/10.4264/numa.79.6_379
https://doi.org/10.4264/numa.79.6_379
Autor:
Hiroto Fujita, Masayasu Kuwahara
Publikováno v:
Handbook of Chemical Biology of Nucleic Acids ISBN: 9789811613135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f003aecd98af0f12310fa8243714c5f3
https://doi.org/10.1007/978-981-16-1313-5_57-1
https://doi.org/10.1007/978-981-16-1313-5_57-1
Autor:
Satoshi Obika, Kenji Mizuguchi, Yuka Kataoka, Hiroto Fujita, Masayasu Kuwahara, Chioko Nagao, Arina Afanaseva, Yuuya Kasahara
Publikováno v:
Biochemistry. 58:493-498
Immunostaining methods have generally been used not only for biological studies but also for clinical diagnoses for decades. However, recently, for these methods, improved rapidity and simplicity have been required for relevant techniques in laborato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3adb73e55170b02872910d4dda963ee
https://doi.org/10.1021/acs.biochem.8b01181
https://doi.org/10.1021/acs.biochem.8b01181