Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Masayasu Akiyama"'
Publikováno v:
New Journal of Chemistry. 25:275-282
To investigate how three-directional molecules behave upon complexation with ferric iron, tripodal 1,3,5-benzene-centered mono-, di- and tritopic iron-chelating ligands {C6H3[CO–(Ahe–(HO)Apr)n–OH]3: 1, n = 1; 2, n = 2; 3, n = 3}, composed of st
Publikováno v:
Inorganic Chemistry. 39:5074-5082
Combining three units of one of H-(alanyl)n-beta-(HO)alanyl peptides (n = 1-3) with nitrilotriacetic acid affords tripodal peptide hydroxamate ligands (1L, 1D, 2LL, 2DL, and 3LLL, where each L or D denotes the L- or D-alanyl residue). These ligands f
Publikováno v:
Journal of Chemical Crystallography. 28:53-56
The structure of the retro-isomer of ferrioxamine E sesqui-hydrate, a ferrioxamine E analog in which the N-hydroxy and carbonyl functions are transposed, was found to be isomorphous with that of ferrioxamine E. The interchange of N and C atoms in the
Autor:
Yukihiro Hara, Masayasu Akiyama
Publikováno v:
Inorganic Chemistry. 35:5173-5180
A pair of linear and cyclic peptide-based trihydroxamate ligands (1 and 2) have been prepared through fragment condensation of suitably protected Ala-Ala-β(HO)Ala units. These ligands have an eight...
Publikováno v:
Bulletin of the Chemical Society of Japan. 65:1356-1361
A nonapeptide with an Ala–(HO)Gly–Ala sequence has been synthesized via condensation of appropriately protected tripeptide units. 1H NMR and CD spectral data indicate that the nonapeptide has a disordered structure in DMSO and water. The peptide
Publikováno v:
Chemistry Letters. 20:1189-1192
Two β-cyclodextrin bound synthetic siderophores that mimic linear and cyclic desferrioxamines are prepared. These synthetic siderophores form stable 1:1 iron(III) complexes with a Δ-selective coordination and show the growth promotion activity when
Autor:
Masayasu Akiyama, Yukihiro Hara
Publikováno v:
Journal of the American Chemical Society. 123(30)
To gain knowledge about biological iron mobilization, tripodal monotopic and ditopic hydroxamate ligands (1 and 2) are prepared, and their iron-chelating properties are investigated. Ligands 1 and 2 contain three Ala-Ala-beta-(HO)Ala units and three
Publikováno v:
Chemistry Letters. 25:915-916
A dodecapeptide trihydroxamate ligand forms a well-defined chiral complex with iron(III) in which this small linear peptide assumes a unique loop conformation, uncommon to protein structures. The complex exhibits siderophore activity for a test micro
Publikováno v:
Chemistry Letters. 24:225-226
New L-alanyl-L-alanyl-β-(N-hydroxy)alanine-based tripodal hydroxamic acids have been prepared. They form stable chiral complexes with iron(III). The chirality of these complexes can be controlled by a tripodal molecule that links to the C-terminus o
Publikováno v:
Bulletin of the Chemical Society of Japan. 57:2456-2462
Acylation of a series of N-benzyloxy α-amino acid derivatives with N,N-phthaloyloglycine shows that the yield decreases with increasing bulkiness of the substituent even by the acyl chloride or mixed anhydride procedure, and that the use of an exces