Zobrazeno 1 - 10
of 298
pro vyhledávání: '"Masayasu, Kojima"'
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionDaily torpor is an active hypothermic phenomenon that is observed in some mammals and birds during fasting. A decrease in blood pressure has also been observed in torpor; however, there remains a lack of knowledge of the underlying mechan
Externí odkaz:
https://doaj.org/article/a39baf009aeb493190a22d0f3b1ac111
Autor:
Takanori Ida, Hatsumi Tominaga, Eri Iwamoto, Akito Kurogi, Ayaka Okura, Kengo Shimada, Johji Kato, Atsutoshi Kuwano, Hirotaka Ode, Sayaka Nagata, Kazuo Kitamura, Takashi Yazawa, Miho Sato-Hashimoto, Masahiro Yasuda, Mikiya Miyazato, Yuki Shiimura, Takahiro Sato, Masayasu Kojima
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Ghrelin is a peptide hormone with various important physiological functions. The unique feature of ghrelin is its serine 3 acyl-modification, which is essential for ghrelin activity. The major form of ghrelin is modified with n-octanoic acid (C8:0) b
Externí odkaz:
https://doaj.org/article/d85534026b95427a8a6a7170dbadf579
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/946aca68c6a945cf960c8021e96df88f
Autor:
Takahiro Sato, Kanae Oishi, Daisuke Koga, Takanori Ida, Yusuke Sakai, Kenji Kangawa, Masayasu Kojima
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Ghrelin, a circulating orexigenic hormone secreted from the stomach, stimulates appetite and food intake by activating the hypothalamic arcuate nucleus. Administration of exogenous ghrelin exerts anabolic effects, causing weight gain, increa
Externí odkaz:
https://doaj.org/article/3760edb0716a4432af266d328de19dbe
Autor:
Hiroko Sano, Akira Nakamura, Mariko Yamane, Hitoshi Niwa, Takashi Nishimura, Kimi Araki, Kazumasa Takemoto, Kei-Ichiro Ishiguro, Hiroki Aoki, Yuzuru Kato, Masayasu Kojima
Publikováno v:
PLoS Biology, Vol 20, Iss 6, p e3001678 (2022)
Cells must adjust the expression levels of metabolic enzymes in response to fluctuating nutrient supply. For glucose, such metabolic remodeling is highly dependent on a master transcription factor ChREBP/MondoA. However, it remains elusive how glucos
Externí odkaz:
https://doaj.org/article/207b80fd7a99461ea601010cac36638a
Autor:
Yuki Shiimura, Shoichiro Horita, Akie Hamamoto, Hidetsugu Asada, Kunio Hirata, Misuzu Tanaka, Kenji Mori, Tomoko Uemura, Takuya Kobayashi, So Iwata, Masayasu Kojima
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Ghrelin is a gastric peptide hormone with important physiological functions, including growth hormone release and appetite-stimulating activity. Here, authors solved the crystal structure of the ghrelin receptor bound to antagonist and suggested a po
Externí odkaz:
https://doaj.org/article/e7526d5cb5754366b7a2d14fcf34c3e1
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The regulation of fetal development by bioactive substances such as hormones and neuropeptides derived from the gestational mother is considered to be essential for the development of the fetus. On the other hand, it has been suggested that changes i
Externí odkaz:
https://doaj.org/article/cdf5087081fc466da697e8c7118448a1
Publikováno v:
Journal of Physical Fitness and Sports Medicine, Vol 6, Iss 3, Pp 125-134 (2017)
Most organisms display various periodicities. Periodicity has been observed in humans in association with sleep, body temperature and hormone secretion. The molecular mechanisms involved are being elucidated by the investigation of clock genes in mam
Externí odkaz:
https://doaj.org/article/afc2d553789b480ba4242d0c80e767e8
Publikováno v:
Frontiers in Endocrinology; 2023, p1-4, 4p
Autor:
Hayao Ohno, Morikatsu Yoshida, Takahiro Sato, Johji Kato, Mikiya Miyazato, Masayasu Kojima, Takanori Ida, Yuichi Iino
Publikováno v:
eLife, Vol 6 (2017)
Peptide signaling controls many processes involving coordinated actions of multiple organs, such as hormone-mediated appetite regulation. However, the extent to which the mode of action of peptide signaling is conserved in different animals is largel
Externí odkaz:
https://doaj.org/article/d1e7d062065b4b3db47ea6a3203902b5