Zobrazeno 1 - 10
of 247
pro vyhledávání: '"Masaya Ueno"'
Autor:
Satoshi Kaito, Kazumasa Aoyama, Motohiko Oshima, Akiho Tsuchiya, Makiko Miyota, Masayuki Yamashita, Shuhei Koide, Yaeko Nakajima-Takagi, Hiroko Kozuka-Hata, Masaaki Oyama, Takao Yogo, Tomohiro Yabushita, Ryoji Ito, Masaya Ueno, Atsushi Hirao, Kaoru Tohyama, Chao Li, Kimihito Cojin Kawabata, Kiyoshi Yamaguchi, Yoichi Furukawa, Hidetaka Kosako, Akihide Yoshimi, Susumu Goyama, Yasuhito Nannya, Seishi Ogawa, Karl Agger, Kristian Helin, Satoshi Yamazaki, Haruhiko Koseki, Noriko Doki, Yuka Harada, Hironori Harada, Atsuya Nishiyama, Makoto Nakanishi, Atsushi Iwama
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract DNA hypomethylating agents (HMAs) are used for the treatment of myeloid malignancies, although their therapeutic effects have been unsatisfactory. Here we show that CRISPR-Cas9 screening reveals that knockout of topoisomerase 1-binding argin
Externí odkaz:
https://doaj.org/article/d5c4ccd82b76400cb577a39dab027bde
Autor:
Kenta Kurayoshi, Yusuke Takase, Masaya Ueno, Kumiko Ohta, Kyoko Fuse, Shuji Ikeda, Takayoshi Watanabe, Yuki Nishida, Shin-ichi Horike, Kazuyoshi Hosomichi, Yuichi Ishikawa, Yuko Tadokoro, Masahiko Kobayashi, Atsuko Kasahara, Yongwei Jing, Mahmoud I. Shoulkamy, Makiko Meguro-Horike, Kensuke Kojima, Hitoshi Kiyoi, Hiroshi Sugiyama, Hiroki Nagase, Atsushi Tajima, Atsushi Hirao
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-11 (2023)
Abstract Differentiation therapy has been proposed as a promising therapeutic strategy for acute myeloid leukemia (AML); thus, the development of more versatile methodologies that are applicable to a wide range of AML subtypes is desired. Although th
Externí odkaz:
https://doaj.org/article/53a9834e70694696afe042ce131cb8fc
Autor:
Elijah Ejun Huang, Ning Zhang, Edward A. Ganio, Huaishuang Shen, Xueping Li, Masaya Ueno, Takeshi Utsunomiya, Masahiro Maruyama, Qi Gao, Ni Su, Zhenyu Yao, Fan Yang, Brice Gaudillière, Stuart B. Goodman
Publikováno v:
Journal of Orthopaedic Translation, Vol 36, Iss , Pp 64-74 (2022)
Background: A critical size bone defect is a clinical scenario in which bone is lost or excised due to trauma, infection, tumor, or other causes, and cannot completely heal spontaneously. The most common treatment for this condition is autologous bon
Externí odkaz:
https://doaj.org/article/1eae0eb5df384bc0963b35da7fbd8efa
Autor:
Hirohito Hirata, Ning Zhang, Masaya Ueno, Danial Barati, Junichi Kushioka, Huaishuang Shen, Masanori Tsubosaka, Masakazu Toya, Tzuhua Lin, Ejun Huang, Zhenyu Yao, Joy Y. Wu, Stefan Zwingenberger, Fan Yang, Stuart B. Goodman
Publikováno v:
Immunity & Ageing, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Despite the high incidence of fractures and pseudoarthrosis in the aged population, a potential role for the use of mesenchymal stem cells (MSCs) in the treatment of bone defects in elderly patients has not been elucidated. Inflam
Externí odkaz:
https://doaj.org/article/4e47b8d5e4ec43a6a039cdfb7fe1fce0
Autor:
Shunsuke Kawano, MD, PhD, Masaya Ueno, MD, PhD, Masanori Fujii, MD, PhD, Daisuke Mawatari, MD, Masaaki Mawatari, MD, PhD
Publikováno v:
Arthroplasty Today, Vol 19, Iss , Pp 101067- (2023)
Background: Prosthetic joint infection, which is caused by implant treatment, is a severe complication. Consequently, silver-containing hydroxyapatite (Ag-HA)-coated implants have been developed to prevent prosthetic joint infection by combining Ag w
Externí odkaz:
https://doaj.org/article/6e2d5f7abfe1433b9349b75dbace3c4c
Publikováno v:
Pain Research and Management, Vol 2023 (2023)
Background. Exercise can reduce the pain threshold momentarily and induce analgesia, which is called exercise-induced hypoalgesia (EIH). Exercise therapy for inducing EIH may be an effective treatment option for pain. We aimed at investigating whethe
Externí odkaz:
https://doaj.org/article/fd2fd51ec4c24201a5caa417e6bcba28
Autor:
Masahiro Maruyama, Chi-Chun Pan, Seyedsina Moeinzadeh, Hunter W. Storaci, Roberto Alfonso Guzman, Elaine Lui, Masaya Ueno, Takeshi Utsunomiya, Ning Zhang, Claire Rhee, Zhenyu Yao, Michiaki Takagi, Stuart B. Goodman, Yunzhi Peter Yang
Publikováno v:
Journal of Orthopaedic Translation, Vol 28, Iss , Pp 90-99 (2021)
Background/Objective: Core decompression (CD) with scaffold and cell-based therapies is a promising strategy for providing both mechanical support and regeneration of the osteonecrotic area for early stage osteonecrosis of the femoral head (ONFH). We
Externí odkaz:
https://doaj.org/article/25ad4d0f3ace44fc9acf86b1fb945e7c
Autor:
Akira Hashimoto, Motoki Sonohata, Hirohito Hirata, Shunsuke Kawano, Shuichi Eto, Masaya Ueno, Masaaki Mawatari
Publikováno v:
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-8 (2021)
Abstract Background Of late, periarticular analgesic injection (PAI) has become a common alternative treatment for pain following total hip arthroplasty (THA). However, the systemic effects of PAI containing corticosteroids in patients subjected to T
Externí odkaz:
https://doaj.org/article/412fcea809304bd18a4c1f02dafc48da
Autor:
Naho Nomura, Chiaki Ito, Takako Ooshio, Yuko Tadokoro, Susumu Kohno, Masaya Ueno, Masahiko Kobayashi, Atsuko Kasahara, Yusuke Takase, Kenta Kurayoshi, Sha Si, Chiaki Takahashi, Masaaki Komatsu, Toru Yanagawa, Atsushi Hirao
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Autophagy is a cellular degradation system contributing to homeostasis of tissue stem cells including haematopoietic stem cells (HSCs). It plays pleiotropic roles in HSC characteristics throughout life, but its stage-specific roles in HSC se
Externí odkaz:
https://doaj.org/article/9b2889ffac5248b398987d01765c8ab0
Autor:
Masaya Ueno, Takuya Tomita, Hiroshi Arakawa, Takahiro Kakuta, Tada-aki Yamagishi, Jumpei Terakawa, Takiko Daikoku, Shin-ichi Horike, Sha Si, Kenta Kurayoshi, Chiaki Ito, Atsuko Kasahara, Yuko Tadokoro, Masahiko Kobayashi, Tsutomu Fukuwatari, Ikumi Tamai, Atsushi Hirao, Tomoki Ogoshi
Publikováno v:
Communications Chemistry, Vol 3, Iss 1, Pp 1-10 (2020)
Quick and accurate measurements of specific metabolites are critical to diagnose certain pathological conditions, but quantification methods for relatively low molecular-weight metabolites are limited. Here, the water-soluble pillar[6]arene is used t
Externí odkaz:
https://doaj.org/article/25681a3ee5eb4ebd828c56a3211c1b2c