Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Masaya Takei"'
Autor:
Sheo B. Singh, Christopher M. Tan, David Kaelin, Peter T. Meinke, Lynn Miesel, David B. Olsen, Hideyuki Fukuda, Ryuta Kishii, Masaya Takei, Kohei Ohata, Tomoko Takeuchi, Taku Shibue, Hisashi Takano, Akinori Nishimura, Yasumichi Fukuda
Publikováno v:
Bioorganicmedicinal chemistry letters. 75
Novel bacterial topoisomerase inhibitors (NBTIs) are the newest members of gyrase inhibitor broad-spectrum antibacterial agents, represented by the most advanced member, gepotidacin, a 4-amino-piperidine linked NBTI, which is undergoing phase III cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88fe127252145bd1368ad8cd0c89f1d
https://pubmed.ncbi.nlm.nih.gov/35609741
https://pubmed.ncbi.nlm.nih.gov/35609741
Autor:
Jingjun Yin, Kouhei Oohata, Peter T. Meinke, Armando Lagrutta, David E. Kaelin, Lynn Miesel, Charles Gill, Hideyuki Fukuda, Charles G. Garlisi, Sheo B. Singh, Yasumichi Fukuda, Christopher M. Tan, Toussaint Nathalie Y, Taku Shibue, Tomoko Takeuchi, Hisashi Takano, Ryuta Kishii, Masaya Takei, David B. Olsen, Akinori Nishimura, Jin Wu, Takayuki Tsuchiya
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:4830-4839
Oxabicyclooctane-linked novel bacterial topoisomerase inhibitors (NBTIs) represent a new class of recently described antibacterial agents with broad-spectrum activity. NBTIs dually inhibit the clinically validated bacterial targets DNA gyrase and top
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d13383dbf940731b0d5857d379597c7
https://doi.org/10.1128/aac.00619-16
https://doi.org/10.1128/aac.00619-16
Autor:
Ryuta Kishii, Carl J. Balibar, Masaya Takei, Charles G. Garlisi, Sheo B. Singh, Katherine Young, Jun Lu, Priya Dayananth, Yasumichi Fukuda, Sookhee Ha
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:3474-3481
Bacterial resistance to antibiotics continues to grow and pose serious challenges, while the discovery rate for new antibiotics declines. Kibdelomycin is a recently discovered natural-product antibiotic that inhibits bacterial growth by inhibiting th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0464db2c243d447cfe2dadd2c0a32f14
https://doi.org/10.1128/aac.00382-15
https://doi.org/10.1128/aac.00382-15
Autor:
Leo A. Joyce, David E. Kaelin, Peter T. Meinke, Takeshi Shibata, Keith W. Rickert, Masaya Takei, Sangita B. Patel, Changqing Wei, Xiu Wang, Xuanjia Peng, David B. Olsen, Armando Lagrutta, Jun Lu, Masanobu Yajima, Yasumichi Fukuda, Jin Wu, Mitsuhito Shibasaki, Hideyuki Fukuda, Lynn Miesel, Christopher M. Tan, Stephen M. Soisson, Todd A. Black, Ryuta Kishii, Robert F. Smith, Ravi P. Nargund, Edward C. Sherer, Hisashi Takano, Sheo B. Singh, Akinori Nishimura
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:1831-1835
Novel bacterial topoisomerase inhibitors (NBTIs) represent a new class of broad-spectrum antibacterial agents targeting bacterial Gyrase A and ParC and have potential utility in combating antibiotic resistance. A series of novel oxabicyclooctane-link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004e6e7ff7e7a7d762ad92dba34bd9d3
https://doi.org/10.1016/j.bmcl.2015.03.044
https://doi.org/10.1016/j.bmcl.2015.03.044
Autor:
Kohei Ohata, Lynn Miesel, Yasumichi Fukuda, Hideyuki Fukuda, Armando Lagrutta, Ryuta Kishii, Peter T. Meinke, Jin Wu, Tomoko Takeuchi, Yonggang Liao, David B. Olsen, Xiu Wang, David E. Kaelin, Takeshi Shibata, Xuanjia Peng, Akinori Nishimura, Christopher M. Tan, Masaya Takei, Changqing Wei, Sheo B. Singh
Publikováno v:
MedChemComm. 6:1773-1780
Novel bacterial topoisomerase inhibitors (NBTIs) are a recent class of broad-spectrum antibacterial agents targeting bacterial DNA gyrase and topoisomerase IV at a site distinct from quinolone binding. They are not cross-resistant to known antibiotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a411fc472d942f6dbae75dc3cc2d655
https://doi.org/10.1039/c5md00297d
https://doi.org/10.1039/c5md00297d
Autor:
Tomoyuki Sugimoto, Hideki Mochizuki, Yuji Nakatsuji, Masaya Takei, Makoto Kinoshita, Kouichiro Hagihara, Josephe A. Honorat, Toru Koda, Tatsusada Okuno, Kazushiro Takata, Saburo Sakoda, Takayuki Tomita
Publikováno v:
Annals of Clinical and Translational Neurology
Objectives The intestinal microflora affects the pathogenesis of several autoimmune diseases by influencing immune system function. Some bacteria, such as lactic acid bacteria, have been reported to have beneficial effects on immune function. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270b13d7956785c2013ed7105df1fc65
https://doi.org/10.1002/acn3.153
https://doi.org/10.1002/acn3.153
Publikováno v:
Antimicrobial Agents and Chemotherapy. 61
Lascufloxacin exhibited a broad spectrum of activity against various clinical isolates. Furthermore, lascufloxacin showed the most potent activity against Gram-positive bacteria among the quinolones tested and incomplete cross-resistance against exis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea69e81ec28413e33513ccf81b8a9df9
https://doi.org/10.1128/aac.00120-17
https://doi.org/10.1128/aac.00120-17
Publikováno v:
International Journal of Automation Technology. 6:669-674
The automation of machining processes requires highly accurate process monitoring. However, the use of additional sensors leads to a significant increase in the cost and reduces the stiffness and reliability of mechanical systems. Hence, we propose a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4c71467f9f57adcd3175790eb5fd092
https://doi.org/10.20965/ijat.2012.p0669
https://doi.org/10.20965/ijat.2012.p0669
Publikováno v:
International Journal of Automation Technology. 5:587-593
Accurate monitoring and adaptive control to maintain optimum machining conditions are required for intelligent machine tools. Methods using additional sensors have been studied to add these functions to machine tools; however, incorporating additiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85742dbe271434159cb6052ae3b7c6d7
https://doi.org/10.20965/ijat.2011.p0587
https://doi.org/10.20965/ijat.2011.p0587
Autor:
Ryuta Kishii, Masaya Takei
Publikováno v:
Journal of Infection and Chemotherapy. 15:361-366
The outer membrane porin protein, OmpF, is widely found in gram-negative bacteria. It is known that the decreased expression of OmpF causes resistance to multiple antibiotics, including quinolones. In order to characterize the influence of decreased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad49b6f12589a4e74c72f039c5e1b45
https://doi.org/10.1007/s10156-009-0716-6
https://doi.org/10.1007/s10156-009-0716-6