Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Masaya Shimanuki"'
Autor:
Manabu Hayata, Masaya Shimanuki, Takehiro Ko, Ryosuke Date, Ami Hamaguchi, Aki Tominaga, Rei Miura, Teruhiko Mizumoto, Masashi Mukoyama
Publikováno v:
Renal Replacement Therapy, Vol 6, Iss 1, Pp 1-6 (2020)
Abstract Background Pembrolizumab, a highly selective humanized monoclonal IgG4κ isotype antibody against PD-1, is one of the immune checkpoint inhibitors approved for treatment of various cancers. The most frequent immune-related adverse events inc
Externí odkaz:
https://doaj.org/article/582ad6bb6cef44799f1ca89eb4ddd0f7
Autor:
Aki Tominaga, Teruhiko Mizumoto, Ryosuke Date, Takehiro Ko, Masaya Shimanuki, Masashi Mukoyama, Rei Miura, Manabu Hayata, Ami Hamaguchi
Publikováno v:
Renal Replacement Therapy, Vol 6, Iss 1, Pp 1-6 (2020)
Background Pembrolizumab, a highly selective humanized monoclonal IgG4κ isotype antibody against PD-1, is one of the immune checkpoint inhibitors approved for treatment of various cancers. The most frequent immune-related adverse events include skin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209f54eece5da814ccbc306031baec17
http://link.springer.com/article/10.1186/s41100-020-00278-9
http://link.springer.com/article/10.1186/s41100-020-00278-9
Autor:
Yongqing Zhang, Satz Mengensatzproduktion, Kazuo Hatanaka, Ji Liu, Poonam Kumari, Hwang Gyun Jeon, Rémy Perdrisot, Hyung-Min Chung, Tiejun Qin, Nobuyoshi Hanaoka, Basab Bagchi, Gi Jin Kim, Per Arne Drabløs, Sandeep Saha, Qi Chen, Marine Diviné, Kodai Kuriyama, Hu Chen, Marta Fichna, Hartmut Merz, Takashi Sonoki, Hiroki Hosoi, Katarzyna Derwich, Veronica Bernard, Druck Reinhardt Druck Basel, Gin-Hyung Hur, Lihui Liu, Shinobu Tamura, Shyamali Dutta, Jyuri Watanuki, Mingjuan Liu, Shogo Murata, Jolanta Rembowska, Bing Li, Hideki Nakakuma, Hye-Sun Kim, Jacob A. Stakkestad, Liping Ye, Sei-Kyung Chang, Li Yu, Doyeun Oh, Danuta Januszkiewicz-Lewandowska, Yue Zhang, Giselle V. Ripoll, Vincent Delwail, Niklas Gebauer, Wolfgang Gebauer, Masaya Shimanuki, Daniel F. Alonso, Mathieu Puyade, Robert Peter Gale, M. Azam Mansoor, Zhijian Xiao, Hye-Gyn Lee, Cécile Tomowiak, Tuphan K. Dolai, Prakas Kumar Mandal, Toshiki Mushino, Hyun-Soo Shin, François Guilhot, Bing Shi, So Young Chong, Moon Ju Jang, Magda Żurawek, Zefeng Xu, Alfred C. Feller, Soumita Choudhuri, Karina Nowicka, Jerzy Nowak, Xiao-Li Du, Natraj Ks, Mokrane Yacoub
Publikováno v:
Acta Haematologica. 129:I-IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cabc76714ffc3d365cb32125be8b0df9
https://doi.org/10.1159/000351401
https://doi.org/10.1159/000351401
Autor:
Takashi Sonoki, Hiroki Hosoi, Keiki Kawakami, Hiroshi Matsuoka, Masaya Shimanuki, Shogo Murata, Hideki Nakakuma, Jyuri Watanuki, Nobuyoshi Hanaoka
Publikováno v:
European Journal of Haematology. 90:59-67
Objectives Malignant cells of mature B-cell origin show tumor-specific clonal immunoglobulin gene (IG) rearrangements, including V(D)J recombinations, nucleotide mutations, or translocations. Rapid molecular cloning of the breakpoint sequence by long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da76f0e0947446ded826e8e01a23b99a
https://doi.org/10.1111/ejh.12037
https://doi.org/10.1111/ejh.12037
Publikováno v:
Cancer Science. 100:1128-1136
Cyclin-dependent kinase (CDK) 1 and the murine double minute 2 homolog (MDM2)-p53 interaction are potential therapeutic targets in cancer, and their inhibition has been reported to be more proapoptotic in malignant cells compared to normal cells. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e13e41ec3ebd7612f954967f30f66d1
https://doi.org/10.1111/j.1349-7006.2009.01150.x
https://doi.org/10.1111/j.1349-7006.2009.01150.x
Autor:
Masato Shikami, Michael Andreeff, Nobuyoshi Hanaoka, Hideki Nakakuma, Kensuke Kojima, Paul G. Corn, Ismael J. Samudio, Vivian Ruvolo, Masaya Shimanuki, Marina Konopleva
Publikováno v:
Leukemia. 22:1728-1736
Activation of the phosphatidylinositol-3 kinase/Akt/mammalian target of the rapamycin (PI3K/Akt/mTOR) pathway and inactivation of wild-type p53 by murine double minute 2 homologue (Mdm2) overexpression are frequent molecular events in acute myeloid l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f76a45a9047cfc1724f277eef76e54
https://doi.org/10.1038/leu.2008.158
https://doi.org/10.1038/leu.2008.158
Autor:
Miwa Kurimoto, Toshiki Mushino, Masaya Shimanuki, Kazuo Hatanaka, Jun Kato, Hideki Nakakuma, Nobuyoshi Hanaoka, Takashi Sonoki, Hiroki Hosoi, Yoshimasa Maeda, Kodai Kuriyama, Shogo Murata, Yasushi Nakamura, Yasuhide Yamamoto
Publikováno v:
Internal medicine (Tokyo, Japan). 53(6)
A 57-year-old Japanese man was admitted to our hospital with diarrhea, weight loss and malabsorption. Due to a high serum IgA level, we suspected α-heavy chain disease (α-HCD). However, no monoclonal IgA was detected on protein electrophoresis or i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a3b28bc507d51f9624662f39c6d92e
https://pubmed.ncbi.nlm.nih.gov/24633028
https://pubmed.ncbi.nlm.nih.gov/24633028
Autor:
Kazuo Hatanaka, Hideki Nakakuma, Jyuri Watanuki, Toshiki Mushino, Nobuyoshi Hanaoka, Shinobu Tamura, Masaya Shimanuki, Kodai Kuriyama, Takashi Sonoki, Hiroki Hosoi, Shogo Murata
Publikováno v:
Acta haematologica. 129(4)
t(8;22)(p11;q11) is a rare but recurrent chromosome translocation that has been reported in 11 cases of myeloproliferative neoplasm or B-acute lymphoblastic leukemia. This translocation results in an in-frame fusion of FGFR1 on 8p11 and BCR on 22q11,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0fedd5fa5ec5e94227882030bdc0523
https://pubmed.ncbi.nlm.nih.gov/23328683
https://pubmed.ncbi.nlm.nih.gov/23328683
Autor:
Hideki Nakakuma, Jiro Kitaura, Mariko Takahashi, Toshio Kitamura, Yutaka Enomoto, Masaya Shimanuki, Naoko Kato, Takashi Sonoki, Koutarou Nishimura
Publikováno v:
International journal of hematology. 96(3)
MicroRNA-125b-1 (miR-125b-1) is a target of the chromosomal translocations t(11;14)(q24;q32) and t(2;11)(p21;q23), which are found in human B-lymphoid and myeloid malignancies, respectively. These translocations result in overexpression of mature miR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3315dd2b853b56a0b28f1fc5220dc4a
https://pubmed.ncbi.nlm.nih.gov/22843432
https://pubmed.ncbi.nlm.nih.gov/22843432
Autor:
Claudia Haferlach, M J S Dyer, Takashi Akasaka, Reiner Siebert, Takashi Sonoki, Tadaichi Kitamura, Hideki Nakakuma, Jyuri Watanuki, Masafumi Taniwaki, Norio Asou, Naoko Kato, Masaya Shimanuki, Hiroyuki Aburatani, Koutarou Nishimura, Kinta Hatakeyama, Jiro Kitaura, Mariko Takahashi, Yutaka Enomoto
Publikováno v:
Leukemia. 25(12)
MicroRNA-125b-1 (miR-125b-1) is a target of a chromosomal translocation t(11;14)(q24;q32) recurrently found in human B-cell precursor acute lymphoblastic leukemia (BCP-ALL). This translocation results in overexpression of miR-125b controlled by immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01fe3e0d4ed1dde78e624322c451c75
https://pubmed.ncbi.nlm.nih.gov/21738213
https://pubmed.ncbi.nlm.nih.gov/21738213