Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Masaya Funaki"'
Autor:
Mika Yoshita, Masaya Funaki, Tetsuro Shimakami, Masaki Kakuya, Kazuhisa Murai, Saiho Sugimoto, Shotaro Kawase, Koji Matsumori, Taro Kawane, Tomoki Nishikawa, Asuka Nakamura, Reo Suzuki, Atsuya Ishida, Narumi Kawasaki, Yuga Sato, Ying-Yi Li, Ariunaa Sumiyadorj, Kouki Nio, Hajime Takatori, Kazunori Kawaguchi, Kazuyuki Kuroki, Takanobu Kato, Masao Honda, Taro Yamashita
Publikováno v:
Viruses, Vol 16, Iss 8, p 1346 (2024)
We developed a novel hepatitis B virus (HBV) infection-monitoring system using a luminescent, 11-amino acid reporter (HiBiT). We performed high-throughput antiviral screening using this system to identify anti-HBV compounds. After the infection of pr
Externí odkaz:
https://doaj.org/article/ea9b0e87ed2448cd98de2ee68561f75c
Autor:
Tomoyuki Hayashi, Kazuya Kitamura, Masaaki Usami, Masaki Miyazawa, Masaki Nishitani, Akihiro Dejima, Makoto Yamamoto, Shotaro Kawase, Masaya Funaki, Noriaki Orita, Hidetoshi Nakagawa, Koki Morita, Noriho Iida, Akihiro Seki, Kouki Nio, Hidenori Kido, Hideo Takayama, Yuta Takeuchi, Shinya Yamada, Hajime Takatori, Mari Shimada, Hiroto Saito, Daisuke Yamamoto, Tadashi Toyama, Taro Yamashita
Publikováno v:
Inflammatory Intestinal Diseases, Pp 1-10 (2023)
Introduction: Leucine-rich alpha-2-glycoprotein (LRG) is a potential biomarker for disease activity and reflects mucosal healing in patients with ulcerative colitis (UC). However, only a few studies have described a detailed sensitivity analysis of L
Externí odkaz:
https://doaj.org/article/7de3a8a913a349b0ae400359edf2e9c2
Autor:
James Ahodantin, Jiapeng Wu, Masaya Funaki, Jair Flores, Xu Wang, Pan Zheng, Yang Liu, Lishan Su
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 3, Pp 101367- (2024)
Background & Aims: Siglec-H is a receptor specifically expressed in mouse plasmacytoid dendritic cells (pDCs), which functions as a negative regulator of interferon-α production and plays a critical role in pDC maturation to become antigen-presentin
Externí odkaz:
https://doaj.org/article/adb7a57e78d64745a19d4434f3c369d7
Autor:
James Ahodantin, Kouki Nio, Masaya Funaki, Xuguang Zhai, Eleanor Wilson, Shyamasundaran Kottilil, Liang Cheng, Guangming Li, Lishan Su
Publikováno v:
JCI Insight, Vol 7, Iss 13 (2022)
Liver diseases have become a major comorbidity health concern for people living with HIV-1 (PLWH) treated with combination antiretroviral therapy (cART). To investigate if HIV-1 infection and cART interact to lead to liver diseases, humanized mice re
Externí odkaz:
https://doaj.org/article/266652df0ec6405d9827f03d1055a1d2
Autor:
Catarina E Hioe, Guangming Li, Xiaomei Liu, Ourania Tsahouridis, Xiuting He, Masaya Funaki, Jéromine Klingler, Alex F Tang, Roya Feyznezhad, Daniel W Heindel, Xiao-Hong Wang, David A Spencer, Guangnan Hu, Namita Satija, Jérémie Prévost, Andrés Finzi, Ann J Hessell, Shixia Wang, Shan Lu, Benjamin K Chen, Susan Zolla-Pazner, Chitra Upadhyay, Raymond Alvarez, Lishan Su
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010183 (2022)
Antibodies are principal immune components elicited by vaccines to induce protection from microbial pathogens. In the Thai RV144 HIV-1 vaccine trial, vaccine efficacy was 31% and the sole primary correlate of reduced risk was shown to be vigorous ant
Externí odkaz:
https://doaj.org/article/fd5aefa035fe437aa866a6e470cde8fa
Autor:
Glenn Hogan, Benjamin Y. Winer, James Ahodantin, Julie Sellau, Tiffany Huang, Florian Douam, Masaya Funaki, Luis Chiriboga, Lishan Su, Alexander Ploss
Chronic hepatitis B (CHB), caused by hepatitis B virus (HBV), remains a major medical problem. HBV has a high propensity for progressing to chronicity and can result in severe liver disease, including fibrosis, cirrhosis and hepatocellular carcinoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72e45c960e615f46b82ab88b04f013a6
https://doi.org/10.1101/2023.05.13.540563
https://doi.org/10.1101/2023.05.13.540563
Autor:
Hajime Takatori, Ariunaa Sumiyadorj, Masaya Funaki, Eishiro Mizukoshi, Masao Honda, Kazuhisa Murai, Tetsuro Shimakami, Taro Yamashita, Shuichi Kaneko, Kazunori Kawaguchi, Takayoshi Shirasaki, Juria Kitabayashi, Christoph Welsch, Kazuya Kitamura, Kuniaki Arai, Tatsuya Yamashita, Tomoaki Nishiyama, Yoshio Sakai
Publikováno v:
The Journal of Infectious Diseases. 226:407-419
Background Many long noncoding RNAs (lncRNAs) have important roles in biological processes. The lncRNA HULC was found to be upregulated in human hepatoma tissues. HULC is thought to be involved in multiple steps of hepatoma development and progressio
Autor:
Catarina E. Hioe, Guangming Li, Xiaomei Liu, Ourania Tsahouridis, Xiuting He, Masaya Funaki, Jéromine Klingler, Alex F. Tang, Roya Feyznezhad, Daniel W. Heindel, Xiao-Hong Wang, David A. Spencer, Guangnan Hu, Namita Satija, Jérémie Prévost, Andrés Finzi, Ann J. Hessell, Shixia Wang, Shan Lu, Benjamin K. Chen, Susan Zolla-Pazner, Chitra Upadhyay, Raymond Alvarez, Lishan Su
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 18, Iss 1, p e1010183 (2022)
PLoS Pathogens, Vol 18, Iss 1, p e1010183 (2022)
Antibodies are principal immune components elicited by vaccines to induce protection from microbial pathogens. In the Thai RV144 HIV-1 vaccine trial, vaccine efficacy was 31% and the sole primary correlate of reduced risk was shown to be vigorous ant
Autor:
Tomoki Nishikawa, Juria Kitabayashi, Takehiro Hayashi, Fanwei Liu, Masaya Funaki, Ryotaro Nakai, Kazuhisa Murai, Taro Yamashita, Masao Honda, Shuichi Kaneko, Takayoshi Shirasaki, Tetsuro Shimakami, Hitoshi Omura, Ariunaa Sumiyadorj
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Hepatitis C virus (HCV) cell culture systems have facilitated the development of efficient direct-acting antivirals against HCV. Huh-7.5, a subline of the human hepatoma cell line Huh-7, has been used widely to amplify HCV because HCV can efficiently
Autor:
Masaya Funaki, Shiho Tanaka, Kazuhisa Murai, Christoph Welsch, Fanwei Liu, Juria Kitabayashi, Tetsuro Shimakami, Hitoshi Omura, Ariunaa Sumiyadorj, Masao Honda, Takayoshi Shirasaki, Tomoki Nishikawa, Shuichi Kaneko
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62
Simeprevir is a novel NS3/4A protease inhibitor (PI) of hepatitis C virus (HCV). The baseline polymorphism NS3-Q80K is frequently observed in genotype (GT) 1a HCV and often associated with treatment failure in simeprevir-containing regimens. We aimed