Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Masaya Arai"'
Autor:
Masaaki Okamoto, Miwa Sasai, Ayumi Kuratani, Daisuke Okuzaki, Masaya Arai, James B. Wing, Shimon Sakaguchi, Masahiro Yamamoto
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112813- (2023)
Summary: Regulatory T (Treg) cells expressing the transcription factor (TF) Foxp3 also express other TFs shared by T helper (Th) subsets under certain conditions. Here, to determine the roles of T-bet-expressing Treg cells, we generate a mouse strain
Externí odkaz:
https://doaj.org/article/039174eb253942a08c8589cb37a7924c
Autor:
Yoshiaki Yasumizu, Naganari Ohkura, Hisashi Murata, Makoto Kinoshita, Soichiro Funaki, Satoshi Nojima, Kansuke Kido, Masaharu Kohara, Daisuke Motooka, Daisuke Okuzaki, Shuji Suganami, Eriko Takeuchi, Yamami Nakamura, Yusuke Takeshima, Masaya Arai, Satoru Tada, Meinoshin Okumura, Eiichi Morii, Yasushi Shintani, Shimon Sakaguchi, Tatsusada Okuno, Hideki Mochizuki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Myasthenia Gravis and thymoma are frequently associated with patients suffering from both diseases. Here the authors perform single cell sequencing of thymoma and find that there are autoimmune antigens such as neuromuscular proteins expressed aberra
Externí odkaz:
https://doaj.org/article/2570824143ef4a838ef3341d99555822
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101694- (2022)
Summary: The establishment of regulatory T cells (Treg)-specific demethylation regions (TSDRs) is essential for the Treg-lineage stability. Here, we present a protocol using bisulfite sequencing to assess Treg-lineage stability. The protocol describe
Externí odkaz:
https://doaj.org/article/56d8e6cfa2a8432eb2ad36787a6e8a54
Autor:
Yoshiaki Yasumizu, Daiki Takeuchi, Reo Morimoto, Yusuke Takeshima, Tatsusada Okuno, Makoto Kinoshita, Takayoshi Morita, Yasuhiro Kato, Min Wang, Daisuke Motooka, Daisuke Okuzaki, Yamami Nakamura, Norihisa Mikami, Masaya Arai, Xuan Zhang, Atsushi Kumanogoh, Hideki Mochizuki, Naganari Ohkura, Shimon Sakaguchi
CD4+T cells are a key mediator of various autoimmune diseases; however, how they contribute to disease development remains obscure primarily because of their cellular heterogeneity. Here, we evaluated CD4+T cell subpopulations by decomposition-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abd3893fb5a677111a90680ae5f7760d
https://doi.org/10.1101/2023.05.09.540089
https://doi.org/10.1101/2023.05.09.540089
Publikováno v:
Journal of the Japan Institute of Metals and Materials. 85:359-365
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd2e8954025556dfe11e33cb9f30120a
https://doi.org/10.2320/jinstmet.j2020062
https://doi.org/10.2320/jinstmet.j2020062
Autor:
Masaru UENOHARA, Michihiro SAKO, Masaya ARAI, Yoshiaki NAOI, Yoshiaki HIRAMOTO, Shinichiro FUJIKAWA
Publikováno v:
Journal of the Japan Society for Technology of Plasticity. 62:183-189
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::774c79807fbe6123071d0fe518118292
https://doi.org/10.9773/sosei.62.183
https://doi.org/10.9773/sosei.62.183
Autor:
Yoshiaki Yasumizu, Naganari Ohkura, Hisashi Murata, Makoto Kinoshita, Soichiro Funaki, Satoshi Nojima, Kansuke Kido, Masaharu Kohara, Daisuke Motooka, Daisuke Okuzaki, Shuji Suganami, Eriko Takeuchi, Yamami Nakamura, Yusuke Takeshima, Masaya Arai, Satoru Tada, Meinoshin Okumura, Eiichi Morii, Yasushi Shintani, Shimon Sakaguchi, Tatsusada Okuno, Hideki Mochizuki
Myasthenia gravis (MG) is a neurological disease caused by autoantibodies against neuromuscular-associated proteins. While MG is frequently developed in thymoma patients, the etiologic factors for MG are not well understood. Here, by constructing a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f9384c9b94f53136872d8f71daa4c0
https://doi.org/10.1101/2021.12.19.473411
https://doi.org/10.1101/2021.12.19.473411
Autor:
Hideto Yuasa, Miho Nishida, Hiroshi Kitagawa, Masaya Arai, Hiroki Tsuruta, Kazuki Miyamoto, Nobuhiko Hoshi, Youhei Mantani, Toshifumi Yokoyama
Publikováno v:
The Journal of Veterinary Medical Science
The effect of bacterial colonies expanded into the intervillous spaces on the localization of several lymphocyte lineages was immunohistochemically investigated in two types of mucosa: ordinary mucosa of rat ileum, which consists of mucosa without an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2418aea3508fb887c72e952a2c4956a5
https://doi.org/10.1292/jvms.18-0734
https://doi.org/10.1292/jvms.18-0734
Autor:
Yohko Kitagawa, Keiko Yasuda, Norihisa Mikami, Masaya Arai, Hitomi Watanabe, Kelvin Y. Chen, Gen Kondoh, Daiya Ohara, Motonao Osaki, Yamami Nakamura, Keiji Hirota, Naganari Ohkura, Shimon Sakaguchi, Ryoji Kawakami, Caleb A. Lareau
Publikováno v:
Immunity. 54(5)
The transcription factor Foxp3 plays crucial roles for Treg cell development and function. Conserved non-coding sequences (CNSs) at the Foxp3 locus control Foxp3 transcription, but how they developmentally contribute to Treg cell lineage specificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0756489f71606474379b0a960ffb09e
https://pubmed.ncbi.nlm.nih.gov/33930308
https://pubmed.ncbi.nlm.nih.gov/33930308
Autor:
Youhei Mantani, Nobuhiko Hoshi, Masaya Arai, Hideto Yuasa, Junichi Kawano, Hiroshi Kitagawa, Toshifumi Yokoyama, Miho Nishida, Chiaki Yoshitomi, Wang-Mei Qi, Natsumi Masuda
Publikováno v:
The Journal of Veterinary Medical Science
The distributions of β-defensin 1 and 2 in secretory host defense system throughout respiratory tract of healthy rats were immunohistochemically investigated. In the nasal epithelium, a large number of non-ciliated and non-microvillous cells (NCs) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefe45750c0202f635300af759966ed1
https://hdl.handle.net/20.500.14094/90004733
https://hdl.handle.net/20.500.14094/90004733