Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Masaya, Ikegawa"'
Autor:
Tatsuya Nakagawa, Naoki Okumura, Masaya Ikegawa, Yumiko Toyama, Takashi Nirasawa, Frederic Mascarelli, Hanielle Vaitinadapoule, Ines Aouimeur, Zhiguo He, Philippe Gain, Gilles Thuret, Noriko Koizumi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Fuchs endothelial corneal dystrophy (FECD) is a slowly evolving, bilateral disease of the corneal endothelium, characterized by an abnormal accumulation of extracellular matrix (ECM) in the basement membrane (Descemet’s membrane, DM). This
Externí odkaz:
https://doaj.org/article/8c59418b36a042c893cb972500c94ff7
Autor:
Rikuya Yoshimura, Tomohiro Miyasaka, Satoru Funamoto, Takashi Saito, Takaomi C. Saido, Masaya Ikegawa, Nobuto Kakuda
Publikováno v:
Brain and Behavior, Vol 13, Iss 4, Pp n/a-n/a (2023)
Abstract The morphology of senile plaques depends on the APP knock‐in mice brain fixative. Solid forms of senile plaques were detected in APP knock‐in mice after formic acid treatment with Davidson's and Bouin's fluid fixative as the brain of AD
Externí odkaz:
https://doaj.org/article/3c18e38d62b04808843b597c50b6b820
Autor:
Hongsun Park, Tomoyuki Yamanaka, Yumiko Toyama, Atsushi Fujita, Hiroshi Doi, Takashi Nirasawa, Shigeo Murayama, Naomichi Matsumoto, Tomomi Shimogori, Masaya Ikegawa, Matti J. Haltia, Nobuyuki Nukina
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder, characterized by the presence of eosinophilic inclusions (NIIs) within nuclei of central and peripheral nervous system cells. This study aims to identify the com
Externí odkaz:
https://doaj.org/article/4f2888696a714b0ab7668db027d5f15c
Publikováno v:
Inflammation and Regeneration, Vol 40, Iss 1, Pp 1-7 (2020)
Abstract Cardiac regenerative therapy is expected to be a promising therapeutic option for the treatment of severe cardiovascular diseases. Artificial tissues or organoids made from cardiovascular cell lineages differentiated from human induced pluri
Externí odkaz:
https://doaj.org/article/d76849c603264cc8bf0fea204819b1d2
Autor:
Naohiko Nakamura, Etsuro Hatano, Kohta Iguchi, Motohiko Sato, Hiroaki Kawaguchi, Iwao Ohtsu, Takaki Sakurai, Nobuhiro Aizawa, Hiroko Iijima, Shuhei Nishiguchi, Takuya Tomono, Yukihiro Okuda, Seidai Wada, Satoru Seo, Kojiro Taura, Shinji Uemoto, Masaya Ikegawa
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background Noninvasive biomarkers are urgently needed for optimal management of nonalcoholic fatty liver disease (NAFLD) for the prevention of disease progression into nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC). I
Externí odkaz:
https://doaj.org/article/9ca8d079cf4744fab5fb156569292f7f
Autor:
Rie Toyomoto, Masatsugu Sakata, Kazufumi Yoshida, Yan Luo, Yukako Nakagami, Teruhisa Uwatoko, Tomonari Shimamoto, Ethan Sahker, Aran Tajika, Hidemichi Suga, Hiroshi Ito, Michihisa Sumi, Takashi Muto, Masataka Ito, Hiroshi Ichikawa, Masaya Ikegawa, Nao Shiraishi, Takafumi Watanabe, Edward R. Watkins, Hisashi Noma, Masaru Horikoshi, Taku Iwami, Toshi A. Furukawa
Publikováno v:
Journal of Affective Disorders. 322:156-162
BACKGROUND: Internet-cognitive behavioural therapy (iCBT) for depression can include multiple components. This study explored depressive symptom improvement prognostic factors (PFs) and effect modifiers (EMs) for five common iCBT components including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3e4aeddfaa7842e24379443e1055d2
https://doi.org/10.1016/j.jad.2022.11.024
https://doi.org/10.1016/j.jad.2022.11.024
Autor:
Masatsugu Sakata, Rie Toyomoto, Kazufumi Yoshida, Yan Luo, Yukako Nakagami, Teruhisa Uwatoko, Tomonari Shimamoto, Aran Tajika, Hidemichi Suga, Hiroshi Ito, Michihisa Sumi, Takashi Muto, Masataka Ito, Hiroshi Ichikawa, Masaya Ikegawa, Nao Shiraishi, Takafumi Watanabe, Ethan Sahker, Yusuke Ogawa, Steven D Hollon, Linda M Collins, Edward R Watkins, James Wason, Hisashi Noma, Masaru Horikoshi, Taku Iwami, Toshi A Furukawa
Publikováno v:
Evidence-Based Mental Health. 25(e1):e18-e25
BackgroundInternet-based cognitive-behavioural therapy (iCBT) is effective for subthreshold depression. However, which skills provided in iCBT packages are more effective than others is unclear. Such knowledge can inform construction of more effectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e889e9e0d08fddcde38314c407ad3e
http://hdl.handle.net/2433/279180
http://hdl.handle.net/2433/279180
Publikováno v:
Applied Sciences, Vol 11, Iss 22, p 11038 (2021)
Matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) is increasingly used in a broad range of research due to its ability to visualize the spatial distribution of metabolites in vivo. Here, we have developed a method, nam
Externí odkaz:
https://doaj.org/article/62968cb0909a47fc86fbb4c4b141c5c9
Autor:
Yuichiro Mita, Kaho Nakayama, Shogo Inari, Yukina Nishito, Yuya Yoshioka, Naoko Sakai, Kanade Sotani, Takahiro Nagamura, Yuki Kuzuhara, Kumi Inagaki, Miki Iwasaki, Hirofumi Misu, Masaya Ikegawa, Toshinari Takamura, Noriko Noguchi, Yoshiro Saito
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Selenoprotein P is secreted by the liver and when present in excess it promotes development of type 2 diabetes. Here the authors develop neutralizing antibodies to target human and mouse selenoprotein P, and show that they improve insulin secretion a
Externí odkaz:
https://doaj.org/article/9072caa59698443ba30fe40fdc34e5b3
Autor:
Nobuto Kakuda, Tomohiro Miyasaka, Noriyuki Iwasaki, Takashi Nirasawa, Satoko Wada-Kakuda, Junko Takahashi-Fujigasaki, Shigeo Murayama, Yasuo Ihara, Masaya Ikegawa
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-8 (2017)
Abstract Amyloid β (Aβ) deposition in the brain is an early and invariable feature of Alzheimer’s disease (AD). The Aβ peptides are composed of about 40 amino acids and are generated from amyloid precursor proteins (APP), by β- and γ-secretase
Externí odkaz:
https://doaj.org/article/4294eb132f5c41ccb8050b1ab2badd8b