Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Masatsugu Nakamura"'
Autor:
Hiroyuki Yoshida, Tokiyoshi Matsushita, Erika Kimura, Yukie Fujita, Robert Keany, Toshihiro Ikeda, Masanao Toshimori, Takahiro Imanaka, Masatsugu Nakamura
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220887 (2019)
Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is characterized by irreversible loss of macular retinal tissue and retinal pigment epithelium (RPE) cells. Several studies have revealed that accumulation of Alu RNA in RPE
Externí odkaz:
https://doaj.org/article/e71ee32534944c7dbe7bc58e3a699a74
Autor:
Taiki Kokubun, Kotaro Yamamoto, Kota Sato, Takahiro Akaishi, Atsushi Shimazaki, Masatsugu Nakamura, Yukihiro Shiga, Satoru Tsuda, Kazuko Omodaka, Toru Nakazawa
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213811 (2019)
PurposeTo investigate the potential of colchicine to improve bleb function after trabeculectomy.MethodsTo find the maximum usable colchicine concentration, an ocular irritation study was performed with the Draize test at concentrations of 0.001%, 0.0
Externí odkaz:
https://doaj.org/article/7acfb32a221c44d4a737c185c0987440
Publikováno v:
Journal of Pharmacological Sciences, Vol 95, Iss 4, Pp 435-442 (2004)
Platelet-activating factor (PAF) plays important roles in allergic reactions. In particular, there are many concerns about PAF, eosinophils, and the chronicity of allergic diseases. The purpose of the present studies is to elucidate the role of PAF i
Externí odkaz:
https://doaj.org/article/75dd1cdb0b594343b52722ea5385138e
Publikováno v:
Clinical Ophthalmology (Auckland, N.Z.)
Hideki Miyake, Naoto Mori, Hidetoshi Mano, Takahiro Imanaka, Masatsugu Nakamura Research and Development Division, Santen Pharmaceutical Co., Ltd., Osaka, Japan Purpose: Reliable measurement of MUC5AC in human tears is essential for elucidation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b79ed23ca81f04d0ac9e5fb8c5edc5
https://doi.org/10.2147/opth.s170552
https://doi.org/10.2147/opth.s170552
Autor:
Kazuko Omodaka, Kotaro Yamamoto, Atsushi Shimazaki, Toru Nakazawa, Taiki Kokubun, Masatsugu Nakamura, Yukihiro Shiga, Satoru Tsuda, Takahiro Akaishi, Kota Sato
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 3, p e0213811 (2019)
PLoS ONE, Vol 14, Iss 3, p e0213811 (2019)
PurposeTo investigate the potential of colchicine to improve bleb function after trabeculectomy.MethodsTo find the maximum usable colchicine concentration, an ocular irritation study was performed with the Draize test at concentrations of 0.001%, 0.0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4daf673fa369ebee050266519a2de0f
http://europepmc.org/articles/PMC6424470
http://europepmc.org/articles/PMC6424470
Autor:
Masatsugu Nakamura, Toru Nakazawa, Hideyuki Saya, Kota Sato, Kazuko Omodaka, Taiki Kokubun, Yukihiro Shiga, Satoru Tsuda, Atsushi Shimazaki, Takahiro Akaishi, Kotaro Yamamoto
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Treatments for refractory glaucoma include trabeculectomy, in which a filtering bleb is created to reduce aqueous pressure. Mitomycin C (MMC) is often used as an adjuvant to reduce post-trabeculectomy bleb scarring and consequent failure. However, sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d94f02f7434a7217c78d2151d78043
https://pubmed.ncbi.nlm.nih.gov/31848363
https://pubmed.ncbi.nlm.nih.gov/31848363
Autor:
Atsuki Fukushima, MD, PhD*1, Ken Fukuda, MD, PhD1, Waka Ishida, PhD1, TatsumaKishimoto, MD1, Masatsugu Nakamura, PhD2, Takashi Nagano, PhD2, TomofumiKageyama, PhD2
Allergic conjunctivitis (AC) and dry eye disease (DED) are inflammatory diseases of the ocular surface. Antigen (Ag) and immunoglobulin E-mediated activation of mast cells in the conjunctiva have a central role in the development of AC. On the other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1204b174fa4599b5a8e2ed625a9b95db
Publikováno v:
Experimental Eye Research. 139:64-72
We investigated the effects of pramipexole, a potent dopamine receptor D2/D3 agonist, on light-induced retinal damage in mice, H2O2-induced retinal pigment epithelium ARPE-19 cell injury in humans, and hydroxyl radical scavenging activity in a cell-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7400dc08e42766806601654a53faff
https://doi.org/10.1016/j.exer.2015.07.007
https://doi.org/10.1016/j.exer.2015.07.007
Autor:
Yuichi Hori, Tomofumi Kageyama, Takatoshi Maeno, Masatsugu Nakamura, Tomoaki Shiba, Asuka Sakamoto
Publikováno v:
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 33(6)
To investigate the short-term effects of 2 new secretagogue eye drops for dry eye, 3% diquafosol tetrasodium ophthalmic solution (diquafosol) and 2% rebamipide ophthalmic suspension (rebamipide), on the concentration of mucin 5AC (MUC5AC) in rabbit t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc79a002d8e0fdeeb7311e7136c3dc6
https://pubmed.ncbi.nlm.nih.gov/28346860
https://pubmed.ncbi.nlm.nih.gov/28346860
Autor:
Osamu Katsuta, Katsuhiko Shinomiya, Masaaki Kageyama, Koji Ohashi, Shin-Ichiro Hirai, Yukie Fujita-Koyama, Masatsugu Nakamura
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)
Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)
Retinal pigment epithelium (RPE) degeneration is a crucial event in dry age-related macular degeneration and gyrate atrophy. The polyamine spermidine has been shown to induce RPE cell death in vitro. The present study aimed to establish a novel in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd25fe672bcb94e5c93e4cbaff60d83
http://europepmc.org/articles/PMC5359532
http://europepmc.org/articles/PMC5359532