Zobrazeno 1 - 10
of 413
pro vyhledávání: '"Masatsugu Horiuchi"'
Autor:
Li-Juan Min, Jun Iwanami, Masachika Shudou, Hui-Yu Bai, Bao-Shuai Shan, Akinori Higaki, Masaki Mogi, Masatsugu Horiuchi
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background To promote understanding of the pathogenesis of cognitive impairment or dementia, we explored the potential interaction between transient cerebral ischemia and amyloid-β (Aβ) infusion in mediating cognitive decline and examined
Externí odkaz:
https://doaj.org/article/0f86a467148b4f5dac9f2f94ed28e921
Autor:
Hikari Takeshita, Koichi Yamamoto, Masaki Mogi, Yu Wang, Yoichi Nozato, Taku Fujimoto, Serina Yokoyama, Kazuhiro Hongyo, Futoshi Nakagami, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Ken Sugimoto, Masatsugu Horiuchi, Hiromi Rakugi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 13 (2021)
Background The activation of AT2 (angiotensin II type 2 receptor ) and Mas receptor by angiotensin II and angiotensin‐(1‐7), respectively, is the primary process that counteracts activation of the canonical renin‐angiotensin system (RAS). Altho
Externí odkaz:
https://doaj.org/article/553dd448b1d244648ed1c40ad46f723a
Autor:
Akinori Higaki, Masaki Mogi, Jun Iwanami, Li‐Juan Min, Hui‐Yu Bai, Bao‐Shuai Shan, Masayoshi Kukida, Toshifumi Yamauchi, Kana Tsukuda, Harumi Kan‐no, Shuntaro Ikeda, Jitsuo Higaki, Masatsugu Horiuchi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 3 (2018)
BackgroundThe classical renin‐angiotensin system is known as the angiotensin (Ang)‐converting enzyme/Ang II/Ang type 1 receptor axis, which induces various organ damage including cognitive decline. The angiotensin‐converting enzyme 2/Ang‐(1
Externí odkaz:
https://doaj.org/article/8b4be77709684c0f8ad221ba36e551b4
Autor:
Akinori Higaki, Masaki Mogi, Jun Iwanami, Li-Juan Min, Hui-Yu Bai, Bao-Shuai Shan, Masayoshi Kukida, Harumi Kan-No, Shuntaro Ikeda, Jitsuo Higaki, Masatsugu Horiuchi
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191708 (2018)
The Morris water maze test (MWM) is one of the most popular and established behavioral tests to evaluate rodents' spatial learning ability. The conventional training period is around 5 days, but there is no clear evidence or guidelines about the appr
Externí odkaz:
https://doaj.org/article/46176277aa094abab489dca89c87ce2d
Autor:
Akinori Higaki, Masaki Mogi, Jun Iwanami, Li-Juan Min, Hui-Yu Bai, Bao-Shuai Shan, Harumi Kan-No, Shuntaro Ikeda, Jitsuo Higaki, Masatsugu Horiuchi
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197003 (2018)
The Morris water maze test (MWM) is a useful tool to evaluate rodents' spatial learning and memory, but the outcome is susceptible to various experimental conditions. Thigmotaxis is a commonly observed behavioral pattern which is thought to be relate
Externí odkaz:
https://doaj.org/article/56fc2814f3074287a7f77501fcc6df69
Autor:
Li-Juan Min, Yodai Kobayashi, Masaki Mogi, Kana Tsukuda, Akio Yamada, Koji Yamauchi, Fumiaki Abe, Jun Iwanami, Jin-Zhong Xiao, Masatsugu Horiuchi
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171515 (2017)
There is a growing interest in identifying natural food ingredients that may serve to prevent dementia such as that due to Alzheimer disease (AD). Peptides derived from food proteins have been demonstrated to have various physiological activities suc
Externí odkaz:
https://doaj.org/article/842e10bf87bb40cab543b8ae06329af1
Autor:
Shin Ito, Masanori Asakura, Yulin Liao, Kyung‐Duk Min, Ayako Takahashi, Kazuhiro Shindo, Satoru Yamazaki, Osamu Tsukamoto, Hiroshi Asanuma, Masaki Mogi, Masatsugu Horiuchi, Yoshihiro Asano, Shoji Sanada, Tetsuo Minamino, Seiji Takashima, Naoki Mochizuki, Masafumi Kitakaze
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 7 (2016)
BackgroundIn cardiac hypertrophy and failure, there is a widespread alteration in mRNA splicing, but the role of splice variants in cardiac hypertrophy has not yet been fully elucidated. In this study, we used an exon array to identify novel splice v
Externí odkaz:
https://doaj.org/article/f0810b27f0bf485987f6ecc3f5d9775b
Autor:
Kana Tsukuda, Masaki Mogi, Jun Iwanami, Harumi Kanno, Hirotomo Nakaoka, Xiao-Li Wang, Hui-Yu Bai, Bao-Shuai Shan, Masayoshi Kukida, Akinori Higaki, Toshifumi Yamauchi, Li-Juan Min, Masatsugu Horiuchi
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167704 (2016)
Browning of white adipose tissue (WAT) has been highlighted as a new possible therapeutic target for obesity, diabetes and lipid metabolic disorders, because WAT browning could increase energy expenditure and reduce adiposity. The new clusters of adi
Externí odkaz:
https://doaj.org/article/56bd01e8c5dc4cc8a981ff10155aff1d
Autor:
Arika Ohnishi, Rie Asayama, Masaki Mogi, Hirotomo Nakaoka, Harumi Kan-No, Kana Tsukuda, Toshiyuki Chisaka, Xiao-Li Wang, Hui-Yu Bai, Bao-Shuai Shan, Masayoshi Kukida, Jun Iwanami, Masatsugu Horiuchi
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117616 (2015)
Citrus fruits are thought to have inhibitory effects on oxidative stress, thereby attenuating the onset and progression of cancer and cardiovascular disease; however, there are few reports assessing their effect on vascular remodeling. Here, we inves
Externí odkaz:
https://doaj.org/article/c7509dae63334c418ab0d84a9761062c
Autor:
Fei Jing, Masaki Mogi, Li-Juan Min, Kousei Ohshima, Hirotomo Nakaoka, Kana Tsukuda, Xiaoli Wang, Jun Iwanami, Masatsugu Horiuchi
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60067 (2013)
We demonstrated that angiotensin II type 2 (AT2) receptor-interacting protein (ATIP) 1 ameliorates inflammation-mediated vascular remodeling independent of the AT2 receptor, leading us to explore the possibility of whether ATIP1 could exert anti-infl
Externí odkaz:
https://doaj.org/article/d5f030701a8d456a8989c001a0b90d9d