Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Masatoshi MAKI"'
Autor:
Ryo Takada, Miki Fujiwara, Masatoshi Maki, Naoyuki Nomura, Shintaro Kono, Akira Fujita, Hiroshi Masumoto, Yoko Takahashi, Yasuhisa Hasegawa, Koji Tamura
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Background Ipilimumab (Ipi) plus nivolumab (Nivo) is the recommended first-line treatment for renal cell carcinoma (RCC). This report describes a case where pancreatic metastases disappeared after only two courses of Ipi + Nivo therapy. The
Externí odkaz:
https://doaj.org/article/520b8f63e6f345f1bc3b0b880b5ef58a
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 9, Iss 1, Pp 1-7 (2023)
Abstract Background While cancer is a risk factor for developing thromboembolism, so is the use of molecularly targeted therapies. This study aimed to determine whether thromboembolism incidence differed between vascular endothelial growth factor (VE
Externí odkaz:
https://doaj.org/article/19222366de48486e9e7f1d03dec4a732
Autor:
Masatoshi Maki, Ryo Takada, Akihiko Taniguchi, Naoyuki Nomura, Seiichiro Kuramoto, Yuki Chiko, Toshiaki Okada, Seiji Saito, Koji Tamura
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Background COVID-19 has become a significant health threat and a primary healthcare concern among the most vulnerable patients with cancer. Patients with COVID-19 who have lung cancer are at great risk and need careful monitoring if they are
Externí odkaz:
https://doaj.org/article/04fdeab9db774fafa447bd5bbde9694a
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-16 (2020)
Abstract The mechanistic target of rapamycin complex 1 (mTORC1) is an essential regulator of cell growth and metabolism through the modulation of protein and lipid synthesis, lysosome biogenesis, and autophagy. The activity of mTORC1 is dynamically r
Externí odkaz:
https://doaj.org/article/3cd1d0a840ca40cbaef928ad37f3d333
Autor:
Yasuo Ariumi, Misao Kuroki, Masatoshi Maki, Masanori Ikeda, Hiromichi Dansako, Takaji Wakita, Nobuyuki Kato
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14517 (2011)
BACKGROUND: Recently, lipid droplets have been found to be involved in an important cytoplasmic organelle for hepatitis C virus (HCV) production. However, the mechanisms of HCV assembly, budding, and release remain poorly understood. Retroviruses and
Externí odkaz:
https://doaj.org/article/bbe5233e69dc4f19b5da5f385a31786e
Autor:
Lin Deng, Yujiao Liang, Adi Ariffianto, Chieko Matsui, Takayuki Abe, Masamichi Muramatsu, Takaji Wakita, Masatoshi Maki, Hideki Shibata, Ikuo Shoji
Publikováno v:
J Virol
We previously reported that hepatitis C virus (HCV) infection activates the reactive oxygen species (ROS)/c-Jun N-terminal kinase (JNK) signaling pathway. However, the roles of ROS/JNK activation in the HCV life cycle remain unclear. We sought to ide
Publikováno v:
Journal of Society of Cosmetic Chemists of Japan. 55:281-287
Autor:
Masatoshi Maki
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 84(4):651-660
The penta-EF-hand (PEF) protein family includes ALG-2 (gene name, PDCD6) and its paralogs as well as classical calpain family members. ALG-2 is a prototypic PEF protein that is widely distributed in eukaryotes and interacts with a variety of proteins
Publikováno v:
International Journal of Molecular Sciences. 24:3923
Environmental factors are important regulators of cell growth and proliferation. Mechanistic target of rapamycin (mTOR) is a central kinase that maintains cellular homeostasis in response to a variety of extracellular and intracellular inputs. Dysreg
Autor:
Nao Nakamura, Nao Ikeda, Hideki Shibata, Yuna Amemiya, Chiaki Ishii, Risa Sugiyama, Masatoshi Maki, Terunao Takahara
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6897, p 6897 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences
Volume 22
Issue 13
Mechanistic target of rapamycin complex 1 (mTORC1) is a master growth regulator by controlling protein synthesis and autophagy in response to environmental cues. Amino acids, especially leucine and arginine, are known to be important activators of mT