Zobrazeno 1 - 10
of 326
pro vyhledávání: '"Masatoshi ITO"'
Autor:
Masatoshi Ito, Natsuko Fujii, Saori Kohara, Masayuki Tanaka, Masaki Takao, Ban Mihara, Yuko Saito, Atsushi Mizuma, Taira Nakayama, Shizuka Netsu, Naoto Suzuki, Akiyoshi Kakita, Eiichiro Nagata
Publikováno v:
Frontiers in Neurology, Vol 14 (2024)
BackgroundAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder associated with progressive impairment of spinal motor neurons. Continuous research endeavor is underway to fully understand the molecular mechanisms associating with
Externí odkaz:
https://doaj.org/article/5d604c3739534125b4b876ac4d42a405
Autor:
Keiko Tanaka, Masafumi Tanaka, Nobuo Watanabe, Masatoshi Ito, Ira Pastan, Masahiro Koizumi, Taiji Matsusaka
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Podoplanin (PDPN) is intensely expressed on the podocyte membrane in an evolutionally conserved manner. CLEC-2, the endogenous ligand of PDPN, is highly expressed in platelets and also exists in a soluble form in plasma. Normally, podocytes
Externí odkaz:
https://doaj.org/article/63a44e4c87434313920b8891f396fd2a
Autor:
Fumiko Konishi, Tadasu Furusho, Yoshiyuki Soeda, Jun Yamauchi, Shoko Kobayashi, Masatoshi Ito, Takuma Araki, Sarasa Kogure, Akihiko Takashima, Susumu Takekoshi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the accumulation of extracellular amyloid-beta peptides (Aβ) resulting in senile plaques and intracellular hyperphosphorylated tau protein resulting in neurofibrill
Externí odkaz:
https://doaj.org/article/13a35b293fc84c849041f2bd9c826ac3
Autor:
Masatoshi Kakizaki, Yuichiro Yamamoto, Shunya Nakayama, Kazuaki Kameda, Etsuko Nagashima, Masatoshi Ito, Takashi Suyama, Yumi Matsuzaki, Tetsuhiro Chiba, Hideaki Sumiyoshi, Yutaka Inagaki, Ai Kotani
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-12 (2021)
Abstract Acute liver injury (ALI) induced by chemicals or viruses can progress rapidly to acute liver failure (ALF), often resulting in death of patients without liver transplantation. Since liver transplantation is limited due to a paucity of donors
Externí odkaz:
https://doaj.org/article/35b3eaf7cd3f40619f7f60fcd1c3efaf
Autor:
Yoko Iijima, Masami Tanaka, Satoko Suzuki, David Hauser, Masayuki Tanaka, Chisa Okada, Masatoshi Ito, Noriko Ayukawa, Yuji Sato, Masato Ohtsuka, Peter Scheiffele, Takatoshi Iijima
Publikováno v:
iScience, Vol 22, Iss , Pp 318-335 (2019)
Summary: Neuronal alternative splicing is a core mechanism for functional diversification. We previously found that STAR family proteins (SAM68, SLM1, SLM2) regulate spatiotemporal alternative splicing in the nervous system. However, the whole aspect
Externí odkaz:
https://doaj.org/article/c163fef950904261823bf6dc9c022b8b
Autor:
Hideki Hayashi, Ting Wang, Masayuki Tanaka, Sanae Ogiwara, Chisa Okada, Masatoshi Ito, Nahoko Fukunishi, Yumi Iida, Ayaka Nakamura, Ayumi Sasaki, Shunji Amano, Kazuhiro Yoshida, Asako Otomo, Masato Ohtsuka, Shinji Hadano
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234180 (2020)
The autophagy-endolysosomal pathway is an evolutionally conserved degradation system that is tightly linked to a wide variety of physiological processes. Dysfunction of this system is associated with many pathological conditions such as cancer, infla
Externí odkaz:
https://doaj.org/article/767051c28519456ab50d9e3404ece691
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190620 (2018)
Migraine attacks alter various molecules that might be related to the pathophysiology of migraine, such as serotonin, calcitonin gene-related peptide, and nitric oxide. The underlying pathophysiology of migraine is as yet unclear. We explored key pro
Externí odkaz:
https://doaj.org/article/baad84ceb1834358a23baf112fad05f5
Publikováno v:
Nihon Kikai Gakkai ronbunshu, Vol 81, Iss 823, Pp 14-00615-14-00615 (2015)
Non-linear viscoelastic behavior of a wormlike micellar solution of cetyltrimethylammonium bromide (CTAB) and sodium salicylate (NaSal) in the large amplitude oscillatory shear (LAOS) is examined. A transient response of the shear stress after applyi
Externí odkaz:
https://doaj.org/article/b1edd96d957b4c69a22fa379e19a6135
Autor:
Mohamed Darwish, Masatoshi Ito, Akinori Takase, Noriko Ayukawa, Satoko Suzuki, Masami Tanaka, Yoko Iijima, Takatoshi Iijima
Thousands of mammalian genes encode alternatively spliced isoforms in their 3’ untranslated region (3’UTR). Alternative 3’UTR diversity may contribute to several neurological processes in developing and adult brains. SAM68 is the key splicing r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4cea5371c74d980463debf39c37568b
https://doi.org/10.1101/2023.04.04.535307
https://doi.org/10.1101/2023.04.04.535307
Autor:
Darwish, Mohamed1,2, Masatoshi Ito3, Yoko Iijima1,4, Akinori Takase3, Noriko Ayukawa4, Satoko Suzuki4, Masami Tanaka4, Kanae Komori5, Daisuke Kaida5, Takatoshi Iijima1,4 takatoshi.iijima@tokai-u.jp
Publikováno v:
Journal of Biological Chemistry. Oct2023, Vol. 299 Issue 10, p1-14. 14p.