Zobrazeno 1 - 10
of 242
pro vyhledávání: '"Masatoshi Maki"'
Autor:
Ryo Takada, Miki Fujiwara, Masatoshi Maki, Naoyuki Nomura, Shintaro Kono, Akira Fujita, Hiroshi Masumoto, Yoko Takahashi, Yasuhisa Hasegawa, Koji Tamura
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Background Ipilimumab (Ipi) plus nivolumab (Nivo) is the recommended first-line treatment for renal cell carcinoma (RCC). This report describes a case where pancreatic metastases disappeared after only two courses of Ipi + Nivo therapy. The
Externí odkaz:
https://doaj.org/article/520b8f63e6f345f1bc3b0b880b5ef58a
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6520 (2024)
Cell death-inducing p53-target protein 1 (CDIP1) is a proapoptotic protein that is normally expressed at low levels and is upregulated by genotoxic and endoplasmic reticulum stresses. CDIP1 has been reported to be localized to endosomes and to intera
Externí odkaz:
https://doaj.org/article/289bfc4e483741ee99a1c0f0e91515fd
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 9, Iss 1, Pp 1-7 (2023)
Abstract Background While cancer is a risk factor for developing thromboembolism, so is the use of molecularly targeted therapies. This study aimed to determine whether thromboembolism incidence differed between vascular endothelial growth factor (VE
Externí odkaz:
https://doaj.org/article/19222366de48486e9e7f1d03dec4a732
Autor:
Masatoshi Maki, Ryo Takada, Akihiko Taniguchi, Naoyuki Nomura, Seiichiro Kuramoto, Yuki Chiko, Toshiaki Okada, Seiji Saito, Koji Tamura
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Background COVID-19 has become a significant health threat and a primary healthcare concern among the most vulnerable patients with cancer. Patients with COVID-19 who have lung cancer are at great risk and need careful monitoring if they are
Externí odkaz:
https://doaj.org/article/04fdeab9db774fafa447bd5bbde9694a
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-16 (2020)
Abstract The mechanistic target of rapamycin complex 1 (mTORC1) is an essential regulator of cell growth and metabolism through the modulation of protein and lipid synthesis, lysosome biogenesis, and autophagy. The activity of mTORC1 is dynamically r
Externí odkaz:
https://doaj.org/article/3cd1d0a840ca40cbaef928ad37f3d333
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3923 (2023)
Environmental factors are important regulators of cell growth and proliferation. Mechanistic target of rapamycin (mTOR) is a central kinase that maintains cellular homeostasis in response to a variety of extracellular and intracellular inputs. Dysreg
Externí odkaz:
https://doaj.org/article/58463d929d0a450e8c12c992f0351645
Autor:
Yuna Amemiya, Nao Nakamura, Nao Ikeda, Risa Sugiyama, Chiaki Ishii, Masatoshi Maki, Hideki Shibata, Terunao Takahara
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6897 (2021)
Mechanistic target of rapamycin complex 1 (mTORC1) is a master growth regulator by controlling protein synthesis and autophagy in response to environmental cues. Amino acids, especially leucine and arginine, are known to be important activators of mT
Externí odkaz:
https://doaj.org/article/e21d571a140e4fdfaa4fa7a5ae4efc25
Autor:
Lin Deng, Yujiao Liang, Adi Ariffianto, Chieko Matsui, Takayuki Abe, Masamichi Muramatsu, Takaji Wakita, Masatoshi Maki, Hideki Shibata, Ikuo Shoji
Publikováno v:
J Virol
We previously reported that hepatitis C virus (HCV) infection activates the reactive oxygen species (ROS)/c-Jun N-terminal kinase (JNK) signaling pathway. However, the roles of ROS/JNK activation in the HCV life cycle remain unclear. We sought to ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9864581f8997dc7574688849c351fe
https://hdl.handle.net/20.500.14094/0100477757
https://hdl.handle.net/20.500.14094/0100477757
Autor:
Ryuta Inukai, Kanako Mori, Keiko Kuwata, Chihiro Suzuki, Masatoshi Maki, Terunao Takahara, Hideki Shibata
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1175 (2021)
Apoptosis-linked gene 2 (ALG-2, also known as PDCD6) is a member of the penta-EF-hand (PEF) family of Ca2+-binding proteins. The murine gene encoding ALG-2 was originally reported to be an essential gene for apoptosis. However, the role of ALG-2 in c
Externí odkaz:
https://doaj.org/article/f194606f89b64ae18156f1ca14a861e7
Autor:
Wei Zhang, Ayaka Muramatsu, Rina Matsuo, Naoki Teranishi, Yui Kahara, Terunao Takahara, Hideki Shibata, Masatoshi Maki
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6315 (2020)
ALG-2 is a penta-EF-hand Ca2+-binding protein and interacts with a variety of proteins in mammalian cells. In order to find new ALG-2-binding partners, we searched a human protein database and retrieved sequences containing the previously identified
Externí odkaz:
https://doaj.org/article/deb9cba10808431d8d6a5a5e5882fb20