Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Masatoshi, Ohnishi"'
Autor:
Kengo Banshoya, Aoi Machida, Saki Kawamura, Tetsuhiro Yamada, Riko Okada, Yui Kawamoto, Hikaru Kimura, Sachi Shibata, Yuhzo Hieda, Yoshiharu Kaneo, Tetsuro Tanaka, Masatoshi Ohnishi
Publikováno v:
Pharmaceutics, Vol 16, Iss 11, p 1462 (2024)
Background/Objectives: Trans-resveratrol (Res) has been reported to possess many biological activities, including neuroprotective effects, owing to its anti-inflammatory and antioxidant properties. However, Res has very low water solubility, which li
Externí odkaz:
https://doaj.org/article/2131447c0cb8475ca14b411f8a64af62
Indoleamine 2, 3-dioxygenase is responsible for low stress tolerance after intracerebral hemorrhage.
Autor:
Masatoshi Ohnishi, Marina Akagi, Mako Kotsuki, Seishi Yonemura, Hikari Aokawa, Maki Yamashita-Ibara, Osamu Yokofujita, Shoji Maehara, Toshiyuki Hata, Atsuko Inoue
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0273037 (2023)
In the chronic phase after intracerebral hemorrhage (ICH), the aftereffect-associated lowering of motivation burdens many patients; however, the pathogenic mechanism is unclear. Here, we revealed for the first time that indoleamine 2, 3-dioxygenase (
Externí odkaz:
https://doaj.org/article/69373d2cd0a543c89677e4a07be4a13f
Publikováno v:
Journal of Neuroimmune Pharmacology.
Autor:
Kengo Banshoya, Makoto Shirakawa, Yuhzo Hieda, Masatoshi Ohnishi, Yuhki Sato, Atsuko Inoue, Tetsuro Tanaka, Yoshiharu Kaneo
Publikováno v:
Chemicalpharmaceutical bulletin. 71(1)
In this study, we developed a water-soluble complex-hydrogel viscosity-controlled formulation of amphotericin B (AmB). AmB is insoluble in water, but borax makes it soluble by forming a complex with AmB. Borax also forms complexes with poly(vinyl alc
Publikováno v:
Neuroscience Letters. 694:215-219
Synergistic expression of cyclooxygenase-2 (COX-2) by interleukin-1β (IL-1β) and bradykinin (BK) in peri-sensory neurons results in the production of prostanoids, which affects sensory neuronal activity and responsiveness and causes hyperalgesia. T
Autor:
Chiaki Fujita, Atsuko Inoue, Masatoshi Ohnishi, Yoshiharu Kaneo, Yuka Hokimoto, Kengo Banshoya, Tetsuro Tanaka
Publikováno v:
International journal of pharmaceutics. 610
The present study focused on the development of an amphotericin B (AmB) nanoformulation for ophthalmic applications. Accordingly, AmB nanohydrogels (AHA/AmB) using alkyl glyceryl hyaluronic acid (Hyalorepair®, AHA), a hydrophobized hyaluronic acid,
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:3-B
Autor:
Masatoshi Ohnishi, Arisa Uda, Jun Kamishikiryo, Hiroyuki Ochiai, Yuta Nakayama, Hiroshi Matsuoka, Marina Akagi, Kohei Matsuoka, Atsuko Inoue, Akiho Shima, Akihiro Michihara
Publikováno v:
Journal of Neuroscience Research. 95:2051-2058
The claudin family comprises four-pass transmembrane proteins involved in the formation of tight junctions (TJs). Relatively recently, claudin domain containing (CLDND) 1, also known as claudin-25, was identified as a novel member of the claudin fami
Autor:
Takao Kai, Atsuko Inoue, Masatoshi Ohnishi, Marina Akagi, Yasunori Yamaguchi, Yukino Yano, Yuui Urabe, Shunpei Tasaka, Yuki Shimizu
Publikováno v:
The Journal of pharmacy and pharmacologyReferences. 72(5)
Objectives Gadolinium (Gd) affects microglial polarization during remyelination. We previously reported that the suppression of proinflammatory microglia was neuroprotective in intracerebral haemorrhage (ICH). The objective of the present study was t
Autor:
Yuui Urabe, Yuki Shimizu, Shunpei Tasaka, Takao Kai, Takuya Shigemasa, Mana Furutaguchi, Atsuko Inoue, Masatoshi Ohnishi, Yukino Yano
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 94:2-P1