Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Masatora Fukuda"'
Publikováno v:
Nucleic Acid Therapeutics. 31:58-67
Site-directed RNA editing is a promising genetic modification technology for therapeutic and pharmaceutical applications. We previously constructed adenosine deaminases acting on RNA (ADAR)-guiding RNAs (AD-gRNAs) that direct A-to-I RNA editing activ
Autor:
Shinichi Sato, Yousuke Katsuda, Kenji Yatsuzuka, Tomoki Kida, Masatora Fukuda, Kathleen Beverly Pe, Hayase Hakariya
Publikováno v:
Nucleic Acids Research
Imaging the dynamics of proteins in living cells is a powerful means for understanding cellular functions at a deeper level. Here, we report a versatile method for spatiotemporal imaging of specific endogenous proteins in living mammalian cells. The
Autor:
Hidefumi Iwashita, Risa Kuramoto, Akinori Oba, Ryoma Noguchi, Kosei Shioji, Noriyoshi Nagahora, Masatora Fukuda, Kentaro Okuma
Publikováno v:
European Journal of Organic Chemistry. 2017:6885-6888
1,4-Dihydrodibenzo[b,h][1,6]naphthyridines were synthesized by the reaction of 2-acetylaminobenzaldehyde with acetophenones in the presence of NaOH. The N-methylation of the dihydrodibenzonaphthyridines with MeI gave 1,1-dimethylammonium iodides. The
Publikováno v:
RNA. 20:392-405
Adenosine-to-inosine (A-to-I) RNA editing is an endogenous regulatory mechanism involved in various biological processes. Site-specific, editing-state–dependent degradation of target RNA may be a powerful tool both for analyzing the mechanism of RN
Autor:
Azusa Nishitarumizu, Masatora Fukuda, Kanako Nose, Hiroyuki Nakagawa, Ryoma Noguchi, Hiromitsu Umeno
Publikováno v:
Scientific Reports
As an alternative to DNA mutagenesis, RNA mutagenesis can potentially become a powerful gene-regulation method for fundamental research and applied life sciences. Adenosine-to-inosine (A-to-I) RNA editing alters genetic information at the transcript
Publikováno v:
RNA. 18:1735-1744
Substitutional RNA editing plays a crucial role in the regulation of biological processes. Cleavage of target RNA that depends on the specific site of substitutional RNA editing is a useful tool for analyzing and regulating intracellular processes re
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:4473-4481
A facile strategy of stepwise molding of a ribonucleopeptide (RNP) complex affords fluorescent RNP sensors with selective dopamine recognition. In vitro selection of a RNA-derived RNP library, a complex of the Rev peptide and its binding site Rev Res
Autor:
Takashi Morii, Masatora Fukuda
Publikováno v:
Seibutsu Butsuri. 48:239-242
Publikováno v:
Genes to cells : devoted to molecularcellular mechanisms. 20(10)
Adenosine-to-Inosine (A-to-I) RNA editing is an intracellular mechanism in which inosine is specifically substituted against adenosine by the action of adenosine deaminases acting on RNA (ADARs). Serotonin 2C receptor (HTR2C) is encoded through combi
Publikováno v:
Journal of the American Chemical Society. 128:12932-12940
Fluorescent biosensors that facilitate reagentless sensitive detection of small molecules are crucial tools in the areas of therapeutics and diagnostics. However, construction of fluorescent biosensors with desired characteristics, that is, detection