Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Masato Yano"'
Autor:
Masato Yugami, Yoshika Hayakawa-Yano, Takahisa Ogasawara, Kazumasa Yokoyama, Takako Furukawa, Hiroe Hara, Kentaro Hashikami, Isamu Tsuji, Hirohide Takebayashi, Shinsuke Araki, Hideyuki Okano, Masato Yano
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108451- (2023)
Summary: Oligodendrocytes (OLs) are the myelin-forming cells in the CNS that support neurons through the insulating sheath of axons. This unique feature and developmental processes are achieved by extrinsic and intrinsic gene expression programs, whe
Externí odkaz:
https://doaj.org/article/d74c3833c99a4893987ac67d95cb9c23
Publikováno v:
FEBS Open Bio, Vol 12, Iss 12, Pp 2179-2190 (2022)
Transmembrane protein 160 (TMEM160) was recently reported to be localized to the mitochondrial inner membrane, but mitochondrial function was noted to be unaffected by loss of TMEM160. In contrast to these previously published findings, we report her
Externí odkaz:
https://doaj.org/article/a42b9249a7514e28a6068006cccca194
Autor:
Dang Minh Tran, Nozomu Yoshioka, Norihisa Bizen, Yukiko Mori-Ochiai, Masato Yano, Shogo Yanai, Junya Hasegawa, Satoshi Miyashita, Mikio Hoshino, Junko Sasaki, Takehiko Sasaki, Hirohide Takebayashi
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 7 (2023)
Externí odkaz:
https://doaj.org/article/5cbc1fa65ddd426cb8b5ad38b16b23e3
Autor:
Masahiro Nogami, Osamu Sano, Keiko Adachi-Tominari, Yoshika Hayakawa-Yano, Takako Furukawa, Hidehisa Iwata, Kazuhiro Ogi, Hideyuki Okano, Masato Yano
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Fused in sarcoma/translated in liposarcoma (FUS) is an RNA-binding protein, and its mutations are associated with neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), through the DNA damage stress response, aberrant stress granu
Externí odkaz:
https://doaj.org/article/2b687065eb9f47e9a3ee4713c74db58a
Autor:
Nozomu Yoshioka, Masayuki Kurose, Masato Yano, Dang Minh Tran, Shujiro Okuda, Yukiko Mori-Ochiai, Masao Horie, Toshihiro Nagai, Ichizo Nishino, Shinsuke Shibata, Hirohide Takebayashi
Publikováno v:
eLife, Vol 11 (2022)
Dystonin (DST), which encodes cytoskeletal linker proteins, expresses three tissue-selective isoforms: neural DST-a, muscular DST-b, and epithelial DST-e. DST mutations cause different disorders, including hereditary sensory and autonomic neuropathy
Externí odkaz:
https://doaj.org/article/cabcf3fd073e457ba5cfb5ea34742533
Autor:
Kazunari Onodera, Daisuke Shimojo, Yasuharu Ishihara, Masato Yano, Fuyuki Miya, Haruhiko Banno, Naoko Kuzumaki, Takuji Ito, Rina Okada, Bruno de Araújo Herculano, Manabu Ohyama, Mari Yoshida, Tatsuhiko Tsunoda, Masahisa Katsuno, Manabu Doyu, Gen Sobue, Hideyuki Okano, Yohei Okada
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-15 (2020)
Abstract Spinal bulbar muscular atrophy (SBMA) is an adult-onset, slowly progressive motor neuron disease caused by abnormal CAG repeat expansion in the androgen receptor (AR) gene. Although ligand (testosterone)-dependent mutant AR aggregation has b
Externí odkaz:
https://doaj.org/article/c9f6034e190445819b495df34c6fae53
Autor:
Masahiro Nogami, Mitsuru Ishikawa, Atsushi Doi, Osamu Sano, Takefumi Sone, Tetsuya Akiyama, Masashi Aoki, Atsushi Nakanishi, Kazuhiro Ogi, Masato Yano, Hideyuki Okano
Publikováno v:
Neurobiology of Disease, Vol 155, Iss , Pp 105364- (2021)
Summary: Fused in sarcoma/translated in liposarcoma (FUS) is a causative gene of amyotrophic lateral sclerosis (ALS). Mutated FUS causes accumulation of DNA damage and cytosolic stress granule (SG) formation, thereby motor neuron (MN) death. However,
Externí odkaz:
https://doaj.org/article/1410dd69c2fd495e97b6d914072ba267
Publikováno v:
Biochemistry and Biophysics Reports, Vol 24, Iss , Pp 100870- (2020)
Mutation in the transmembrane protein 65 gene (TMEM65) results in mitochondrial dysfunction and a severe mitochondrial encephalomyopathy phenotype. However, neither the function of TMEM65 nor the cellular responses to its depletion have been fully el
Externí odkaz:
https://doaj.org/article/1db603b520f74803969c4b1b7887b303
Autor:
Nozomu Yoshioka, Yudai Kabata, Momona Kuriyama, Norihisa Bizen, Li Zhou, Dang M. Tran, Masato Yano, Atsushi Yoshiki, Tatsuo Ushiki, Thomas J. Sproule, Riichiro Abe, Hirohide Takebayashi
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 5 (2020)
Loss-of-function mutations in dystonin (DST) can cause hereditary sensory and autonomic neuropathy type 6 (HSAN-VI) or epidermolysis bullosa simplex (EBS). Recently, DST-related diseases were recognized to be more complex than previously thought beca
Externí odkaz:
https://doaj.org/article/1be9fe63694c464d9f7dca7326f58544
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231450 (2020)
RNA-binding proteins (RBPs) control many types of post-transcriptional regulation, including mRNA splicing, mRNA stability, and translational efficiency, by directly binding to their target RNAs and their mutation and dysfunction are often associated
Externí odkaz:
https://doaj.org/article/5314bc75258e44dbb474dacb972dfeb8