Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Masato Terakawa"'
Autor:
Masataka Katashima, Fumiaki Koizumi, Manabu Murakami, Hiromitsu Kageyama, Akihiro Ohnishi, Masato Terakawa
Publikováno v:
Clinical Pharmacology & Therapeutics. 66:501-508
Purpose We compared the pharmacokinetics of the inhaled novel neutrophil elastase inhibitor FK706 between healthy nonsmokers and smokers. Methods Six healthy nonsmokers and six smokers inhaled 50 to 400 mg FK706 in two different doses. Series of plas
Autor:
Atsunori Kaibara, Masato Terakawa, Kiyoshi Yamaoka, Kenji Tabata, Takehisa Hata, Shingo Suzuki
Publikováno v:
Drug Metabolism and Pharmacokinetics. 14:286-293
A computer program, MOMENT (EXCEL), for moment analysis was developed on Microsoft Excel®. MOMENT (EXCEL) written in Visual Basic for Applications® can handle time course not only of blood concentration but also of urinaly or bilialy excretion acco
Autor:
Toshifumi Shiraga, Shin-ichi Ninomiya, Kouji Takeshita, Yoshio Esumi, Yoshinori Teramura, Akio Kawamura, Akira Kagayama, Masato Terakawa
Publikováno v:
Drug Metabolism and Pharmacokinetics. 14:385-391
The penetration and absorption of tacrolimus (FK506) in the skin of rat after a single topical application of 14C-labeled FK506 (14C-FK506) ointment under occlusive dressing was studied by semimicroautoradiography of the skin and by counting radioact
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 25:603-613
Autor:
Koji Ishibashi, Toshiaki Amamoto, Akinori Urae, Hiromitsu Kageyama, Nami Iyota, Masato Terakawa, Shin Irie
Publikováno v:
Drug Metabolism and Pharmacokinetics. 9:793-798
The effect of food intake on the bioavailability of vamicamide, a new anticholinergic drug, was studied in six healthy male volunteers. Each subject, in a two-way crossover manner, was given a single 18-mg oral dose of vamicamide after overnight fast
Autor:
Nami Iyota, Masato Terakawa
Publikováno v:
Drug Metabolism and Pharmacokinetics. 9:799-808
The pharmacokinetic data of vamicamide, a new anticholinergic drug, collected from healthy male subjects were analysed to estimate population pharmacokinetic parameters. A total of 48 subjects participated in three single-dose studies and three multi
Autor:
Masato Terakawa, Mitsuyoshi Nalcashima, Akira Sugiyama, Mitsutaka Kanamaru, Toshihiko Uematsu, S. Nagashima, Atsuhiro Mizuno
Publikováno v:
The Journal of Clinical Pharmacology. 33:1122-1131
The pharmacokinetics, and aldose reductase (AR) inhibitory and uricosuric activities of FK366 were studied in healthy volunteers given a single oral dose of 150, 300, or 600 mg after fasting, 600 mg after a meal, or 300 mg twice a day for 8 days afte
Publikováno v:
Drug Metabolism and Pharmacokinetics. 8:515-520
Publikováno v:
Drug Metabolism and Pharmacokinetics. 8:1047-1056
The pharmacokinetics of quinotolast sodium, a new anti-allergic drug, were studied in six elderly and six young healthy male volunteers after single oral dosing with 5mg of the drug. The mean maximum plasma concentration of unchanged drug increased s
Autor:
Koji Ishibashi, Masataka Katashima, Hisayuki Sekino, Masato Terakawa, Seiichi Fujiwara, Noboru Nakamichi
Publikováno v:
Drug Metabolism and Pharmacokinetics. 8:1029-1040
Quinotolast sodium, a new anti-allergic drug, was studied in six healthy male volunteers to evaluate its pharmacokinetics in steady-state conditions after oral dosing. The subjects were given a single dose of 5mg, and after a two-day washout period,