Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Masato Nakashima"'
Autor:
Masafumi Sawada, Han Matsuda, Yasuhiko Tanzawa, Kei Sakamoto, Hiroe Kudo, Masato Nakashima, Tetsuo Ikezono
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Several surgical techniques have been documented for approaching and repairing superior semicircular canal dehiscence syndrome (SCDS). These techniques encompass the trans-middle cranial fossa, transmastoid, endoscopic approaches, and round window re
Externí odkaz:
https://doaj.org/article/6cc6f7572d3c44b784db09cf055a9b59
Autor:
Tetsuaki Hiyoshi, Fuqiang Zhao, Rina Baba, Takeshi Hirakawa, Ryosuke Kuboki, Kazunori Suzuki, Yoshiro Tomimatsu, Patricio O’Donnell, Steve Han, Neta Zach, Masato Nakashima
Publikováno v:
Skeletal Muscle, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Background The lack of functional dystrophin protein in Duchenne muscular dystrophy (DMD) causes chronic skeletal muscle inflammation and degeneration. Therefore, the restoration of functional dystrophin levels is a fundamental approach for
Externí odkaz:
https://doaj.org/article/37c9543e3555496fbea14e74b74662d0
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0207969 (2019)
Activation of the muscarinic M1 receptor is a promising approach to improve cognitive deficits associated with cholinergic dysfunction in Alzheimer's disease, dementia with Lewy bodies, and schizophrenia. TAK-071 is an M1-selective positive allosteri
Externí odkaz:
https://doaj.org/article/9eb42a220ef7469e846e76032424432b
Autor:
Misawa Niki Ishii, Masato Nakashima, Hidenori Kamiguchi, Neta Zach, Ryosuke Kuboki, Rina Baba, Takeshi Hirakawa, Kazunori Suzuki, Maria Quinton
Publikováno v:
Neuromuscular Disorders. 33:302-308
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec2926834cdf0937e2380f51cac9b99c
https://doi.org/10.1016/j.nmd.2023.02.003
https://doi.org/10.1016/j.nmd.2023.02.003
Autor:
Rebecca Evans, Haruhide Kimura, Masato Nakashima, Takashi Ishikawa, Hiroshi Yukitake, Motohisa Suzuki, James Hazel, Hélène Faessel, Jingtao Wu, Yaming Hang, Robert Alexander, Laura Rosen, Deborah S. Hartman, Emiliangelo Ratti
Publikováno v:
Journal of Sleep Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b2ee4334095be19c07b3f91f8ebd609
https://doi.org/10.1111/jsr.13878
https://doi.org/10.1111/jsr.13878
Autor:
Yasutaka Hoashi, Masaharu Nakayama, Takafumi Takai, Keisuke Hirai, Masato Nakashima, Osamu Uchikawa, Tatsuki Koike, Yohei Kosugi
Publikováno v:
Journal of medicinal chemistry. 64(6)
To develop potent and orally bioavailable melatonin receptor (MT1 and MT2) agonists, a novel series of 5-6-5 tricyclic derivatives was designed, synthesized, and evaluated. The synthesized indeno[5,4-d][1,3]oxazole, cyclopenta[c]pyrazolo[1,5-a]pyridi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2928d1c8ceb8aa1fe999fb72b361d660
https://pubmed.ncbi.nlm.nih.gov/33682410
https://pubmed.ncbi.nlm.nih.gov/33682410
Autor:
Takahiko Taniguchi, Yuki Ito, Haruka Imada, Masato Nakashima, Hiroki Iwashita, Noriko Suzuki, Eri Shiraishi, Maki Miyamoto
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 365:179-188
The pathophysiology of schizophrenia has been associated with glutamatergic dysfunction. Modulation of the glutamatergic signaling pathway, including N-methyl-d-aspartate (NMDA) receptors, can provide a new therapeutic target for schizophrenia. Phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45ca9abdeb26f084b89cb07e917608f6
https://doi.org/10.1124/jpet.117.245506
https://doi.org/10.1124/jpet.117.245506
Autor:
Shuhei Ikeda, Hironori Kokubo, Masato Nakashima, Shinji Nakamura, Hideyuki Oki, Noriko Uchiyama, Takahiko Taniguchi, Masanori Kawasaki, Hua Zou, Nobuyuki Negoro, Satoshi Mikami, Tomoko Ashizawa, Yuuki Itou, Yuuto Hiura, Hiroki Iwashita, Izumi Nomura, Maki Miyamoto, Isaac Hoffman
Publikováno v:
CHEMICAL & PHARMACEUTICAL BULLETIN. 65:1058-1077
It has been hypothesized that selective inhibition of phosphodiesterase (PDE) 2A could potentially be a novel approach to treat cognitive impairment in neuropsychiatric and neurodegenerative disorders through augmentation of cyclic nucleotide signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e31421eb699528cc923d333db0f7978b
https://doi.org/10.1248/cpb.c17-00564
https://doi.org/10.1248/cpb.c17-00564
Publikováno v:
Behavioural brain research. 376
Changes in the cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) signaling are implicated in older people with dementia. Drugs that modulate the cAMP/cGMP levels in the brain might therefore provide new therapeutic optio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37e110189a67485f24c30b43c5cf72e
https://pubmed.ncbi.nlm.nih.gov/31521738
https://pubmed.ncbi.nlm.nih.gov/31521738
