Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Masato Kubo"'
Autor:
Ruka Setoguchi, Tomoya Sengiku, Hiroki Kono, Eiryo Kawakami, Masato Kubo, Tadashi Yamamoto, Shohei Hori
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The mechanisms by which the number of memory CD8 T cells is stably maintained remains incompletely understood. It has been postulated that maintaining them requires help from CD4 T cells, because adoptively transferred memory CD8 T cells per
Externí odkaz:
https://doaj.org/article/00548985a7f64998903cf455d5eeac07
Autor:
Jia‐Chen Liu, Ke Zhang, Xu Zhang, Fei Guan, Hu Zeng, Masato Kubo, Pamela Lee, Fabio Candotti, Louisa Katherine James, Niels Olsen Saraiva Camara, Kamel Benlagha, Jia‐Hui Lei, Huamei Forsman, Lu Yang, Wei Xiao, Zheng Liu, Chao‐Hong Liu
Publikováno v:
MedComm, Vol 5, Iss 8, Pp n/a-n/a (2024)
Abstract Maturation of the secondary antibody repertoire requires class‐switch recombination (CSR), which switches IgM to other immunoglobulins (Igs), and somatic hypermutation, which promotes the production of high‐affinity antibodies. Following
Externí odkaz:
https://doaj.org/article/b12782f9506642e8a5b259d22218e319
Autor:
Takuya Nara, Hiroshi Shimoda, Chitose Suzuki, Ngo Thuy Bao Tran, Hina Tsukada, Hiroki Okayama, Hu Weiyin, Miho Obata, Saki Mitsunaga, Masashi Sakurai, Yudai Kuroda, Ken Maeda, Masato Kubo, Takashi Saito, Kenichi Masuda
Publikováno v:
Veterinary Vaccine, Vol 3, Iss 1, Pp 100055- (2024)
Feline infectious peritonitis (FIP) is a lethal disease caused by a pathogenic coronavirus, feline infectious peritonitis virus (FIPV), in cats. Effective vaccines have been unsuccessful due to the frequent mutation of FIPV and antibody-dependent enh
Externí odkaz:
https://doaj.org/article/59bee0a222b34b719a86dd7b4fee02fc
Autor:
Tomohiko Kimura, Masato Kubo, Kaio Takahashi, Ryo Wamata, Yuichiro Iwamoto, Hideyuki Iwamoto, Yukino Katakura, Junpei Sanada, Yoshiro Fushimi, Masashi Shimoda, Fuminori Tatsumi, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Publikováno v:
Journal of Diabetes Research, Vol 2024 (2024)
Recently, the development of once-weekly incretin-based injections dulaglutide and semaglutide has drawn a great deal of attention. This study is aimed at comparing the efficacy of once-weekly GLP-1 receptor activator (GLP-1RA) dulaglutide and semagl
Externí odkaz:
https://doaj.org/article/873bcbed9174489c991de2c7ce9e3dfe
Autor:
Yuichiro Iwamoto, Tomohiko Kimura, Fuminori Tatsumi, Toshitomo Sugisaki, Masato Kubo, Erina Nakao, Kazunori Dan, Ryo Wamata, Hideyuki Iwamoto, Kaio Takahashi, Junpei Sanada, Yoshiro Fushimi, Yukino Katakura, Masashi Shimoda, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Decreased pancreatic volume, increased pancreatic fat mass, and serrated pancreatic margins are characteristic morphological changes of the pancreas in subjects with type 2 diabetes mellitus. This retrospective study aimed to clarify the cli
Externí odkaz:
https://doaj.org/article/bdc55c535807462f937576312f677c6f
Autor:
Jianing Tang, Lu Yang, Fei Guan, Heather Miller, Niels Olsen Saraiva Camara, Louisa K. James, Kamel Benlagha, Masato Kubo, Steffen Heegaard, Pamela Lee, Jiahui Lei, Hu Zeng, Chengwei He, Zhimin Zhai, Chaohong Liu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Raptor, a key component of mTORC1, is required for recruiting substrates to mTORC1 and contributing to its subcellular localization. Raptor has a highly conserved N-terminus domain and seven WD40 repeats, which interact with mTOR and other mTORC1-rel
Externí odkaz:
https://doaj.org/article/0d328c9cd93a4c8391cd74c645fd80f7
Autor:
Yukai Jing, Li Luo, Ying Chen, Lisa S. Westerberg, Peng Zhou, Zhiping Xu, Andrés A. Herrada, Chan-Sik Park, Masato Kubo, Heng Mei, Yu Hu, Pamela Pui-Wah Lee, Bing Zheng, Zhiwei Sui, Wei Xiao, Quan Gong, Zhongxin Lu, Chaohong Liu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-13 (2021)
Abstract The SARS-CoV-2 infection causes severe immune disruption. However, it is unclear if disrupted immune regulation still exists and pertains in recovered COVID-19 patients. In our study, we have characterized the immune phenotype of B cells fro
Externí odkaz:
https://doaj.org/article/35a91ff1e9094bd4a733b8cae92b770c
Autor:
Chihiro Tomiaki, Kosuke Miyauchi, Sewon Ki, Yoshie Suzuki, Narumi Suzuki, Hiroshi Morimoto, Yohei Mukoyama, Masato Kubo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Asthma is airway inflammatory diseases caused by the activation of group 2 innate lymphoid cells (ILC2s) and type 2 helper T (TH2) cells. Cysteine proteases allergen cause tissue damage to airway epithelial cells and activate ILC2-mediated type 2 air
Externí odkaz:
https://doaj.org/article/be2dfe588a88442ca6768b21e211dc24
Autor:
Kosuke Miyauchi, Yu Adachi, Keisuke Tonouchi, Taiki Yajima, Yasuyo Harada, Hidehiro Fukuyama, Senka Deno, Yoichiro Iwakura, Akihiko Yoshimura, Hideki Hasegawa, Katsuyuki Yugi, Shin-ichiro Fujii, Osamu Ohara, Yoshimasa Takahashi, Masato Kubo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The reasons why influenza infection promotes a broader antibody response compared with vaccines are not fully understood. Here the authors show that unmasking of haemagglutinin epitopes and IL-4 signals in the germinal centre contribute to broader an
Externí odkaz:
https://doaj.org/article/439271e19f7845d6b2e4d127336088a7
Autor:
Shiru Chen, Fei Guan, Fabio Candotti, Kamel Benlagha, Niels Olsen Saraiva Camara, Andres A. Herrada, Louisa K. James, Jiahui Lei, Heather Miller, Masato Kubo, Qin Ning, Chaohong Liu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
B cells secrete antibodies and mediate the humoral immune response, making them extremely important in protective immunity against SARS-CoV-2, which caused the coronavirus disease 2019 (COVID-19) pandemic. In this review, we summarize the positive fu
Externí odkaz:
https://doaj.org/article/2e91db76813647e8b8fa138b1dc2533b