Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Masato Kitajima"'
Publikováno v:
Trauma Case Reports, Vol 42, Iss , Pp 100722- (2022)
In an aging society, the number of femoral fractures is increasing, as well as the incidence of periprosthetic fractures. These secondary fractures are often difficult to fixate stably because of the osteoporotic bone and the existence of the former
Externí odkaz:
https://doaj.org/article/d4cc3ae258054f8daa790f3eb58640b5
Autor:
Yusuke Kamiya, Hiroka Takaku, Rio Yamada, Chisato Akase, Yuto Abe, Yuko Sekiguchi, Norie Murayama, Makiko Shimizu, Masato Kitajima, Fumiaki Shono, Kimito Funatsu, Hiroshi Yamazaki
Publikováno v:
Toxicology Reports, Vol 7, Iss , Pp 149-154 (2020)
Apparent permeability coefficients (Papp) across a human intestinal epithelial Caco-2 cell monolayer were measured for a range of industrial/drug chemicals. A predictive equation for determining in vitro Papp values of fifty-six substances was set up
Externí odkaz:
https://doaj.org/article/9557e1483da744628f3cc82b26068693
Publikováno v:
Trauma Case Reports, Vol 37, Iss , Pp 100601- (2022)
Atypical femoral fractures (AFF) are more difficult to treat than typical femoral fractures; they require strong fixation and good reduction. Intramedullary (IM) nailing is the first option for the treatment of complete AFF; however, there are few re
Externí odkaz:
https://doaj.org/article/e2cccdd0e75044bd9e45e38c573a6714
Publikováno v:
Trauma Case Reports, Vol 36, Iss , Pp 100542- (2021)
Aside from cases of mechanical complications or infection short femoral nails (SFNs) are not removed after open reduction and internal fixation (ORIF) because femoral trochanteric fractures often occur in older osteoporotic females. Occasionally, SFN
Externí odkaz:
https://doaj.org/article/27eb277719b04e86af36a85e3e98470f
Autor:
Hirokazu Takai, Masato Kitajima, Seiko Takai, Tomoki Takahashi, Ken-ichi Katsura, Makoto Tokunaga, Susumu Watanabe
Publikováno v:
Case Reports in Orthopedics, Vol 2021 (2021)
The changes occurring in knee osteoarthritis often cause alterations in the spinal loading condition, which further lead to degenerative changes. This close relationship of the knee and spine has been reported as knee-spine syndrome. A 60-year-old wo
Externí odkaz:
https://doaj.org/article/a66eee42205346d18a0698c8355324e9
Autor:
Yusuke Kamiya, Junya Ohori, Fumiaki Shono, Hiroshi Yamazaki, Kimito Funatsu, Tomonori Miura, Masato Kitajima, Makiko Shimizu, Kentaro Handa
Publikováno v:
Chemical Research in Toxicology. 34:2180-2183
Updated algorithms for predicting the volumes of systemic circulation (V1), along with absorption rate constants and hepatic intrinsic clearances, as input parameters for physiologically based pharmacokinetic (PBPK) models were established to improve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b14c6e1400ec26e6aaeb7ea68c33b0e6
https://doi.org/10.1021/acs.chemrestox.1c00249
https://doi.org/10.1021/acs.chemrestox.1c00249
Autor:
Tomonori Miura, Hiroshi Yamazaki, Makiko Shimizu, Yusuke Kamiya, Fumiaki Shono, Shiori Hina, Kazuki Shigeta, Kentaro Handa, Kimito Funatsu, Masato Kitajima, Mayu Yanagi
Publikováno v:
Chemical Research in Toxicology. 34:507-513
Recently developed computational models can estimate plasma, hepatic, and renal concentrations of industrial chemicals in rats. Typically, the input parameter values (i.e., the absorption rate constant, volume of systemic circulation, and hepatic int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f7927d9db1fd624515ec9842beb7fe4
https://doi.org/10.1021/acs.chemrestox.0c00336
https://doi.org/10.1021/acs.chemrestox.0c00336
Autor:
Masato Kitajima, Yusuke Kamiya, Makiko Shimizu, Fumiaki Shono, Tomonori Miura, Yui Kobayashi, Manae Yoshizawa, Kimito Funatsu, Ayane Nakano, Hiroshi Yamazaki, Shohei Otsuka, Miyu Iwasaki
Publikováno v:
Chemical Research in Toxicology. 33:1736-1751
Recently developed high-throughput in vitro assays in combination with computational models could provide alternatives to animal testing. The purpose of the present study was to model the plasma, hepatic, and renal pharmacokinetics of approximately 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8269ea8bb3258338504c20ef37180df1
https://doi.org/10.1021/acs.chemrestox.0c00009
https://doi.org/10.1021/acs.chemrestox.0c00009
Autor:
Yuto Abe, Makiko Shimizu, Masato Kitajima, Hiroka Takaku, Norie Murayama, Chisato Akase, Fumiaki Shono, Hiroshi Yamazaki, Yusuke Kamiya, Kimito Funatsu, Rio Yamada, Yuko Sekiguchi
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 149-154 (2020)
Toxicology Reports, Vol 7, Iss, Pp 149-154 (2020)
Graphical abstract
Highlights • Permeability values of 90 industry chemicals were measured by a Caco-2 system. • A multivariate prediction equation for permeability of chemicals was proposed. • Chemical permeability coefficients were inver
Highlights • Permeability values of 90 industry chemicals were measured by a Caco-2 system. • A multivariate prediction equation for permeability of chemicals was proposed. • Chemical permeability coefficients were inver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c5783d147c1b6602eac31840b9f1c9
http://europepmc.org/articles/PMC6976901
http://europepmc.org/articles/PMC6976901
Autor:
Kentaro Handa, Masato Kitajima, Makiko Shimizu, Hiroshi Yamazaki, Tomonori Miura, Airi Kato, Yusuke Kamiya, Junya Ohori
Publikováno v:
Biologicalpharmaceutical bulletin. 45(1)
Physiologically based pharmacokinetic (PBPK) modeling has the potential to play significant roles in estimating internal chemical exposures. The three major PBPK model input parameters (i.e., absorption rate constants, volumes of the systemic circula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a2b599c674885fa51a7a44c960691e
https://pubmed.ncbi.nlm.nih.gov/34732590
https://pubmed.ncbi.nlm.nih.gov/34732590