Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Masato Hosokawa"'
Autor:
Kazunori Sano, Yasushi Iwasaki, Yuta Yamashita, Keiichi Irie, Masato Hosokawa, Katsuya Satoh, Kenichi Mishima
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Serine 129 (S129) phosphorylation of α-synuclein (αSyn) is a central feature of Lewy body (LB) disease pathology. Although the neighboring tyrosine residues Y125, Y133, and Y136 are also phosphorylation sites, little is known regarding pot
Externí odkaz:
https://doaj.org/article/8339408d5c114b4fb7b233af1180672c
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 815 (2022)
Exosomes are nano-sized extracellular vesicles that are known to carry various messages to distant cells. It was recently reported that cancer-derived exosomes are orientated to metastatic organs. However, there are no reports on drug carrier develop
Externí odkaz:
https://doaj.org/article/171b0ac2d5a74b27ac46b186669e9cfa
Autor:
Genjiro Suzuki, Sei Imura, Masato Hosokawa, Ryu Katsumata, Takashi Nonaka, Shin-Ichi Hisanaga, Yasushi Saeki, Masato Hasegawa
Publikováno v:
eLife, Vol 9 (2020)
Abnormal α-synuclein aggregation has been implicated in several diseases and is known to spread in a prion-like manner. There is a relationship between protein aggregate structure (strain) and clinical phenotype in prion diseases, however, whether d
Externí odkaz:
https://doaj.org/article/0f2caa9f013b48efad937ae9e57f26aa
Autor:
Masato Hosokawa, Hiromi Kondo, Geidy E. Serrano, Thomas G. Beach, Andrew C. Robinson, David M. Mann, Haruhiko Akiyama, Masato Hasegawa, Tetsuaki Arai
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract In 2006, mutations in the granulin gene were identified in patients with familial Frontotemporal Lobar Degeneration. Granulin transcript haploinsufficiency has been proposed as a disease mechanism that leads to the loss of functional progran
Externí odkaz:
https://doaj.org/article/afd44deb62a8416980a2d0acb1a3fb39
Autor:
Masato Hosokawa, Tetsuaki Arai, Masami Masuda-Suzukake, Takashi Nonaka, Makiko Yamashita, Haruhiko Akiyama, Masato Hasegawa
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52389 (2012)
In neurodegenerative disorders, abnormally hyperphosphorylated and aggregated tau accumulates intracellularly, a mechanism which is thought to induce neuronal cell death. Methylene blue, a type of phenothiazine, has been reported to inhibit tau aggre
Externí odkaz:
https://doaj.org/article/89ea75920ebc412aba8bcf1565ed51e7
Autor:
Masato HOSOKAWA, Shuhei SUGIYAMA, Takeshi SUGIURA, Yusuke KUBO, Masahiro SAWADA, Kotaro YAMASHITA, Keisuke SUZUKI, Takayoshi SAITO, Daisuke SUDO
Publikováno v:
Rigakuryoho Kagaku. 37:191-195
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9af26409c0101ebd30aba58cbad435aa
https://doi.org/10.1589/rika.37.191
https://doi.org/10.1589/rika.37.191
Publikováno v:
Molecular Medicine Reports. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c058355ba92cbb61a2f3b852f253eda
https://doi.org/10.3892/mmr.2023.12949
https://doi.org/10.3892/mmr.2023.12949
Autor:
Takumi Kakimoto, Masato Hosokawa, Mayuko Ichimura-Shimizu, Hirohisa Ogawa, Yuko Miyakami, Satoshi Sumida, Koichi Tsuneyama
Publikováno v:
Pathology - Research and Practice. 247:154525
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0093d45210dcfe353e23b031194aed29
https://doi.org/10.1016/j.prp.2023.154525
https://doi.org/10.1016/j.prp.2023.154525
Autor:
Genjiro Suzuki, Hiroshi Shitara, Tetsuaki Arai, Masato Hasegawa, Aki Shimozawa, Hiromi Kondo, Masato Hosokawa, William Campbell, Masami Masuda-Suzukake, Takashi Nonaka
Publikováno v:
Brain. 145:349-361
The phenomenon of ‘prion-like propagation’ in which aggregates of abnormal amyloid-fibrilized protein propagate between neurons and spread pathology, is attracting attention as a new mechanism in neurodegenerative diseases. There is a strong corr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1b35a8a13495e09b21b3b357557df6
https://doi.org/10.1093/brain/awab289
https://doi.org/10.1093/brain/awab289
Autor:
Masato Hosokawa, Daisuke Sudo, Shoki Yamaguchi, Masafumi Itokazu, Takayoshi Saito, Keisuke Suzuki
Publikováno v:
Journal of physical therapy science. 34(11)
[Purpose] We aimed to determine whether lower leg muscle echo intensity, an indicator of muscle quality, is a useful predictor of gait variability after examining the relationship between physical activity and gait variability in community-dwelling o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48b0e6aec38b5c2e58840f461280253
https://pubmed.ncbi.nlm.nih.gov/36337213
https://pubmed.ncbi.nlm.nih.gov/36337213