Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Masato, Ogura"'
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0246630 (2021)
Interleukin-31 (IL-31) is involved in excessive development of cutaneous sensory nerves in atopic dermatitis (AD), leading to severe pruritus. We previously reported that PQA-18, a prenylated quinolinecarboxylic acid (PQA) derivative, is an immunosup
Externí odkaz:
https://doaj.org/article/64ba96e4525d4e43b388bfb21435271f
Publikováno v:
Neurochemical Research. 45:1020-1033
Astrocytes release exosomes that regulate neuronal cell function. 1-methyl-4-phenylpyridinium (MPP+) is a well-known neurotoxin used to induce cell death in in vitro Parkinson's disease models, and microRNA (miRNA) transferred by released exosomes ca
Autor:
Toshiyuki Suzuki, Haruhisa Kikuchi, Masato Ogura, Miwako K Homma, Yoshiteru Oshima, Yoshimi Homma
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117088 (2015)
Mitochondria play a key role in diverse processes including ATP synthesis and apoptosis. Mitochondrial function can be studied using inhibitors of respiration, and new agents are valuable for discovering novel mechanisms involved in mitochondrial reg
Externí odkaz:
https://doaj.org/article/dc1f246c8d2f4f5eabeef44aaa6bf1ad
Autor:
Takeshi Takarada, Miki Kou, Noritaka Nakamichi, Masato Ogura, Yuma Ito, Ryo Fukumori, Hiroshi Kokubo, Gabriela B Acosta, Eiichi Hinoi, Yukio Yoneda
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63947 (2013)
We have previously shown marked upregulation of the mRNA and corresponding protein for the cellular motor molecule myosin VI (Myo6) after an extremely traumatic stress experience, along with a delayed decrease in 5-bromo-2'-deoxyuridine incorporation
Externí odkaz:
https://doaj.org/article/9b39d88e43b84ac189b90c9770bb0568
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:4-B
Autor:
Masato Ogura, Ikuo Wada
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:1
Autor:
Masato Ogura, Takami Kakuda, Takeshi Takarada, Noritaka Nakamichi, Ryo Fukumori, Yeong-Hun Kim, Eiichi Hinoi, Yukio Yoneda
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48270 (2012)
BackgroundWe previously demonstrated the functional expression in newborn rat neocortical astrocytes of glutamine transporter (GlnT = slc38a1) believed to predominate in neurons over astroglia in the brain. In order to evaluate the possible role of t
Externí odkaz:
https://doaj.org/article/6be3c02f5822483ba4a1d03f12b6fc99
Publikováno v:
Neurochemical research. 45(5)
Astrocytes release exosomes that regulate neuronal cell function. 1-methyl-4-phenylpyridinium (MPP
Autor:
Haruhisa Kikuchi, Masato Ogura, Junko Yamaki, Yoshiteru Oshima, Toshiyuki Suzuki, Miwako K. Homma, Norshalena Shakespear, Yoshimi Homma
Publikováno v:
Biochemical pharmacology. 162
The development of neuroprotective agents is necessary for the treatment of neurodegenerative diseases. Here, we report PQA-11, a prenylated quinolinecarboxylic acid (PQA) derivative, as a potent neuroprotectant. PQA-11 inhibits glutamate-induced cel
Autor:
Masato Ogura, Haruhisa Kikuchi, Toshiyuki Suzuki, Yoshimi Homma, Miwako K. Homma, Yoshiteru Oshima
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:66-72
Mitochondrial uncoupling is one of the therapeutic strategies used to control energy metabolism in various metabolic diseases and in obesity. Ppc-1 ( 1 ), a prenylated quinolinecarboxylic acid isolated from cellular slime molds, shows uncoupling acti