Zobrazeno 1 - 10
of 542
pro vyhledávání: '"Masato, Hasegawa"'
Autor:
Fuyuki Kametani, Marina Tahira, Masaki Takao, Tomoyasu Matsubara, Kazuko Hasegawa, Mari Yoshida, Yuko Saito, Shigeo Murayama, Masato Hasegawa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Our previous cryogenic electron microscopy (cryoEM) analysis showed that the core structures of α-synuclein filaments accumulated in brains of patients diagnosed with dementia with Lewy bodies (DLB) and multiple system atrophy (MSA) patient
Externí odkaz:
https://doaj.org/article/9e5fa5e47de84ff9b3cc3071115f4a92
Autor:
Osamu Yokota, Tomoko Miki, Hanae Nakashima-Yasuda, Hideki Ishizu, Takashi Haraguchi, Chikako Ikeda, Masato Hasegawa, Akinori Miyashita, Takeshi Ikeuchi, Naoto Nishikawa, Shintaro Takenoshita, Koichiro Sudo, Seishi Terada, Manabu Takaki
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-24 (2024)
Abstract Agyrophilic grains (AGs) are age-related limbic-predominant lesions in which four-repeat tau is selectively accumulated. Because previous methodologically heterogeneous studies have demonstrated inconsistent findings on the relationship betw
Externí odkaz:
https://doaj.org/article/e40d2050a9d34e42a9b032d3ca1df442
Autor:
Tomoyasu Matsubara, Kenji Ishii, Yoko Saito, Aya Midori Tokumaru, Akira Arakawa, Manato Hara, Masanori Kurihara, Renpei Sengoku, Kazutomi Kanemaru, Atsushi Iwata, Tomio Arai, Akinori Miyashita, Takeshi Ikeuchi, Masato Hasegawa, Shigeo Murayama, Yuko Saito
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/8a51de4650cf4603b783f749acca242b
Autor:
Tatsuhiko Sano, Tetsuya Nagata, Satoe Ebihara, Kie Yoshida-Tanaka, Ayako Nakamura, Asuka Sasaki, Aki Shimozawa, Hideki Mochizuki, Toshiki Uchihara, Masato Hasegawa, Takanori Yokota
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract In Parkinson's disease and other synucleinopathies, fibrillar forms of α-synuclein (aSyn) are hypothesized to structurally convert and pathologize endogenous aSyn, which then propagates through the neural connections, forming Lewy pathologi
Externí odkaz:
https://doaj.org/article/ab3ae3bd3fb0435899aa972613e4bc0b
Autor:
Kohji Mori, Kazue Shigenobu, Goichi Beck, Ryota Uozumi, Yuto Satake, Maki Suzuki, Shizuko Kondo, Shiho Gotoh, Yuki Yonenobu, Makiko Kawai, Yuki Suzuki, Yuko Saito, Eiichi Morii, Masato Hasegawa, Hideki Mochizuki, Shigeo Murayama, Manabu Ikeda
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-11 (2023)
Abstract Right temporal variant frontotemporal dementia, also called right-predominant semantic dementia, often has an unclear position within the framework of the updated diagnostic criteria for behavioral variant frontotemporal dementia or primary
Externí odkaz:
https://doaj.org/article/18432a8218e74f4fa7ea24c3dcb0226d
Autor:
Airi Tarutani, Sofia Lövestam, Xianjun Zhang, Abhay Kotecha, Andrew C. Robinson, David M. A. Mann, Yuko Saito, Shigeo Murayama, Taisuke Tomita, Michel Goedert, Sjors H. W. Scheres, Masato Hasegawa
Publikováno v:
FEBS Open Bio, Vol 13, Iss 8, Pp 1394-1404 (2023)
The formation of amyloid filaments through templated seeding is believed to underlie the propagation of pathology in most human neurodegenerative diseases. A widely used model system to study this process is to seed amyloid filament formation in cult
Externí odkaz:
https://doaj.org/article/e6a04ddc628d42669dccef432f209b08
Autor:
Ahmed Imtiaz, Shotaro Shimonaka, Mohammad Nasir Uddin, Montasir Elahi, Koichi Ishiguro, Masato Hasegawa, Nobutaka Hattori, Yumiko Motoi
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
The efficacy of current treatments is still insufficient for Alzheimer’s disease (AD), the most common cause of Dementia. Out of the two pathological hallmarks of AD amyloid-β plaques and neurofibrillary tangles, comprising of tau protein, tau pat
Externí odkaz:
https://doaj.org/article/160579159a284f1596db2265a64b6963
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-12 (2023)
Abstract Tunnelling Nanotubes (TNTs) facilitate contact-mediated intercellular communication over long distances. Material transfer via TNTs can range from ions and intracellular organelles to protein aggregates and pathogens. Prion-like toxic protei
Externí odkaz:
https://doaj.org/article/30b17a8cf2c048d692577a0c2a5b2580
Autor:
Chao Qi, Masato Hasegawa, Masaki Takao, Motoko Sakai, Mayasuki Sasaki, Masashi Mizutani, Akio Akagi, Yasushi Iwasaki, Hiroaki Miyahara, Mari Yoshida, Sjors H. W. Scheres, Michel Goedert
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-7 (2023)
Abstract Subacute sclerosing panencephalitis (SSPE) occurs in some individuals after measles infection, following a symptom-free period of several years. It resembles chronic traumatic encephalopathy (CTE), which happens after repetitive head impacts
Externí odkaz:
https://doaj.org/article/c9ac974ed6f04aa48888758c49e72cbf
Autor:
Hung-Chieh Chung, Miho Seike, Nobuyoshi Kawabata, Masato Hasegawa, Shen-Wen Chien, Tzu-Sheng Shen
Publikováno v:
Journal of Asian Architecture and Building Engineering, Vol 21, Iss 3, Pp 806-824 (2022)
To increase the knowledge of bus evacuation in tunnel fire scenarios, we investigated the bus evacuation flow rate in the event of a tunnel fire, starting with a video analysis of the 2012 Hsuehshan tunnel fire in Taiwan, to gain a preliminary unders
Externí odkaz:
https://doaj.org/article/6df8e03d14bd48f98db80e9a62b7b16f