Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Masataka Tajima"'
Autor:
Takeshi Aoyama, Kenji Nakano, Takeshi Yuasa, Erika Sugiyama, Takako Okawa, Kazuyuki Ito, Keiichi Azuma, Koki Hashimoto, Ryota Furutani, Makoto Hiraide, Kazuo Kobayashi, Kenichi Suzuki, Jyunnichi Tomomatsu, Masataka Tajima, Hitoshi Sato, Toshihiro Hama, Shunji Takahashi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The safety and effectiveness of pazopanib are related to plasma trough concentrations in renal cell carcinoma (RCC); however, data on pazopanib plasma trough concentrations with soft tissue sarcoma (STS) are limited. This study investigated
Externí odkaz:
https://doaj.org/article/980b2c0f97b242018c4d72bbb6d25e96
Autor:
Michiru Nagao, Masataka Tajima, Erika Sugiyama, Ryosuke Shinouchi, Keita Shibata, Masayuki Yoshikawa, Takushi Yamamoto, Vilasinee Hirunpanich Sato, Koji Nobe, Hitoshi Sato
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 2, Pp n/a-n/a (2022)
Abstract In clinical practice, pregabalin is orally administered for neuropathic pain, but causes severe central nervous system side effects, such as dizziness, which results in dose limitation or discontinuation. To reduce the central side effects o
Externí odkaz:
https://doaj.org/article/4208057013bb4cbdb8c876be3f9ad652
Autor:
Tomokazu Suzuki, Erika Sugiyama, Kenji Nozawa, Masataka Tajima, Kyoka Takahashi, Masayoshi Yoshii, Hidenori Suzuki, Vilasinee H. Sato, Hitoshi Sato
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 2, Pp n/a-n/a (2021)
Abstract This study sought to investigate whether dosing frequency (the number of doses per day) affects the antimicrobial efficacy and safety of ampicillin/sulbactam (ABPC/SBT) in Japanese elderly pneumonia patients treated with ABPC/SBT at 6 g/day.
Externí odkaz:
https://doaj.org/article/0bc461bab6184c24b98f2f8e29bf0d75
Autor:
Kazunori Mori, Vilasinee Hirunpanich Sato, Hitoshi Sato, Akira Ota, Masataka Tajima, Erika Sugiyama
Publikováno v:
Pharmacological Reports
Background Silver is a transition metal that is known to be less toxic than platinum. However, only few studies have reported the anticancer effects of some silver complexes and their possibility as an alternative to platinum complex. This study inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e211bc361deb6adf8f08b130d55b6483
https://doi.org/10.1007/s43440-021-00260-0
https://doi.org/10.1007/s43440-021-00260-0
Autor:
Koki Hashimoto, Erika Sugiyama, Mitsukuni Suenaga, Kazuyoshi Kawakami, Hiyori Kidokoro, Takeru Wakatsuki, Masataka Tajima, Keisho Chin, Eiji Shinozaki, Hitoshi Sato, Takashi Ichimura, Yuichi Minowa, Wataru Suzuki, Yasuhiro Nakano, Izuma Nakayama, Kazuo Kobayashi, Mariko Ogura, Toshihiro Hama, Daisuke Takahari, Akira Ooki, Tomoko Hiraoka, Kensei Yamaguchi, Takashi Yokokawa, Takeshi Aoyama, Kenichi Suzuki
Publikováno v:
Cancer Chemotherapy and Pharmacology. 87:767-777
The association between the pharmacokinetics and pharmacodynamics of regorafenib, a multiple tyrosine kinase inhibitor, remains unclear. This study assessed the trough plasma concentrations (Ctrough) of regorafenib and its N-oxide (M2) and N-oxide/de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1414a8d60a33ea5f0ecd45f3a5647e0a
https://doi.org/10.1007/s00280-021-04237-x
https://doi.org/10.1007/s00280-021-04237-x
Autor:
Hitoshi Sato, Makoto Hiraide, Takeshi Aoyama, Yusuke Iikura, Kenichi Suzuki, Koki Hashimoto, Erika Sugiyama, Kazuo Kobayashi, Toshihiro Hama, Takashi Yokokawa, Masataka Tajima, Sari Shikibu
Publikováno v:
In Vivo
Background/Aim: Immune-related adverse events (irAEs) are associated with the efficacy of immune-checkpoint inhibitors in patients with melanoma and non-small cell lung cancer. We therefore evaluated the relationship between irAEs and nivolumab effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0094822dfd00d6094c05dfa673921f8d
https://doi.org/10.21873/invivo.12083
https://doi.org/10.21873/invivo.12083
Publikováno v:
Med Cannabis Cannabinoids
Background: Cannabidiol (CBD) is highly lipophilic, and its oral bioavailability is known to be very low in humans. In this study, we developed a novel nanoemulsion preparation of CBD (CBD-NE) to improve the poor solubility and absorption of CBD. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54eeb639f62b76c1f41d1360b28cc931
https://doi.org/10.1159/000497361
https://doi.org/10.1159/000497361
Autor:
Masayoshi Yoshii, Hitoshi Sato, Kyoka Takahashi, Erika Sugiyama, Hidenori Suzuki, Vilasinee Hirunpanich Sato, Kenji Nozawa, Tomokazu Suzuki, Masataka Tajima
Publikováno v:
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 9, Iss 2, Pp n/a-n/a (2021)
Pharmacology Research & Perspectives, Vol 9, Iss 2, Pp n/a-n/a (2021)
This study sought to investigate whether dosing frequency (the number of doses per day) affects the antimicrobial efficacy and safety of ampicillin/sulbactam (ABPC/SBT) in Japanese elderly pneumonia patients treated with ABPC/SBT at 6 g/day. This was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7f8f0c4109f0c7a313b560057b37aa
https://pubmed.ncbi.nlm.nih.gov/33764686
https://pubmed.ncbi.nlm.nih.gov/33764686
Autor:
Erika Sugiyama, Yukako Nakano, Masataka Tajima, Michiru Nagao, Vilasinee Hirunpanich Sato, Makoto Inada, Hitoshi Sato
Publikováno v:
Cannabis Cannabinoid Res
Introduction: Cannabidiol (CBD) is known to affect the pharmacokinetics of other drugs through metabolic inhibition of CYP2C19 and CYP3A4. However, there is a lack of in vivo evidence for such drug interactions. Therefore, we investigated the saturab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b87bf041273bb2ffaa9f068a33c4633
https://europepmc.org/articles/PMC7759266/
https://europepmc.org/articles/PMC7759266/
Autor:
Kazuo, Kobayashi, Erika, Sugiyama, Eiji, Shinozaki, Takeru, Wakatsuki, Masataka, Tajima, Hiyori, Kidokoro, Takeshi, Aoyama, Yasuhiro, Nakano, Kazuyoshi, Kawakami, Koki, Hashimoto, Mitsukuni, Suenaga, Takashi, Ichimura, Mariko, Ogura, Keisho, Chin, Izuma, Nakayama, Akira, Ooki, Daisuke, Takahari, Wataru, Suzuki, Takashi, Yokokawa, Yuichi, Minowa, Tomoko, Hiraoka, Kenichi, Suzuki, Hitoshi, Sato, Toshihiro, Hama, Kensei, Yamaguchi
Publikováno v:
Cancer chemotherapy and pharmacology. 87(6)
The association between the pharmacokinetics and pharmacodynamics of regorafenib, a multiple tyrosine kinase inhibitor, remains unclear. This study assessed the trough plasma concentrations (CThe CWe analyzed 43 patients who received regorafenib 40-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::687ca22118e4c3f81f4066baa2865042
https://pubmed.ncbi.nlm.nih.gov/33635392
https://pubmed.ncbi.nlm.nih.gov/33635392