Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Masataka Suzuki"'
Autor:
Ada Irmak Özcan, Arianexys Aquino Lόpez, Alexandra N. Wolff, Audrey Ma, Amanda Rosewell Shaw, Masataka Suzuki, Malcolm K. Brenner, Mary K. McKenna
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101279- (2024)
Systemic delivery of oncolytic and immunomodulatory adenoviruses may be required for optimal effects on human malignancies. Mesenchymal stromal cells (MSCs) can serve as delivery systems for cancer therapeutics due to their ability to transport and s
Externí odkaz:
https://doaj.org/article/bca70b3e6e2c445b940f2f3be75993c5
Autor:
Pattama Wiriyasermkul, Satomi Moriyama, Masataka Suzuki, Pornparn Kongpracha, Nodoka Nakamae, Saki Takeshita, Yoko Tanaka, Akina Matsuda, Masaki Miyasaka, Kenji Hamase, Tomonori Kimura, Masashi Mita, Jumpei Sasabe, Shushi Nagamori
Publikováno v:
eLife, Vol 12 (2024)
Transporter research primarily relies on the canonical substrates of well-established transporters. This approach has limitations when studying transporters for the low-abundant micromolecules, such as micronutrients, and may not reveal physiological
Externí odkaz:
https://doaj.org/article/712df96a4ef54e3b881a8aba60b55281
Autor:
Hsuan-Chen Liu, Andrew Sikora, Caroline Porter, Allison Nipper, Emilie AK Warren, Gabrielle Wells, Mariana Villanueva, Hugo Villanueva, Masataka Suzuki
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/d31f36e2c1224194b5f73a41735c53cd
Publikováno v:
Molecular Therapy: Oncolytics, Vol 23, Iss , Pp 571-581 (2021)
Adenoviruses are well characterized and thus easily modified to generate oncolytic vectors that directly lyse tumor cells and can be “armed” with transgenes to promote lysis, antigen presentation, and immunostimulation. Oncolytic adenoviruses (OA
Externí odkaz:
https://doaj.org/article/ab2e398736ad433cb85891d8c8c779f2
Autor:
Amanda Rosewell Shaw, Caroline E. Porter, Tiffany Yip, Way-Champ Mah, Mary K. McKenna, Matthew Dysthe, Youngrock Jung, Robin Parihar, Malcolm K. Brenner, Masataka Suzuki
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Rosewell Shaw et al. show that a previously developed immunotherapy strategy, coupling oncolytic adenoviral immunotherapy with clinically tested HER2-specific CAR T-cells, is effective against pancreatic ductal adenocarcinoma (PDAC). This combination
Externí odkaz:
https://doaj.org/article/6c619b9e136441a696783c518011c56f
Autor:
Amanda Rosewell Shaw, Masataka Suzuki
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 15, Iss , Pp 418-429 (2019)
Adenoviruses are a commonly utilized virus for gene therapy platforms worldwide. Since adenovirus components are characterized as highly immunogenic, their immunogenicity inhibits the widespread use of adenoviral vectors to treat genetic disorders. H
Externí odkaz:
https://doaj.org/article/50df80ba26214a9c986894ff6d85c771
Autor:
Masataka Suzuki, Takayoshi Toba, Yu Izawa, Hiroshi Fujita, Keisuke Miwa, Yu Takahashi, Hiroyuki Toh, Hiroyuki Kawamori, Hiromasa Otake, Hidekazu Tanaka, Sei Fujiwara, Yoshiaki Watanabe, Atsushi K. Kono, Kenji Okada, Ken‐ichi Hirata
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 18 (2021)
Background Myocardial extracellular volume fraction (ECV), measured by cardiac magnetic resonance imaging, is a useful prognostic marker for patients who have undergone aortic valve replacement (AVR) for aortic stenosis. However, the prognostic signi
Externí odkaz:
https://doaj.org/article/7922af1df2534575b67b9e6188b1353a
Publikováno v:
Cancers, Vol 14, Iss 11, p 2769 (2022)
For decades, Adenoviruses (Ads) have been staple cancer gene therapy vectors. Ads are highly immunogenic, making them effective adjuvants. These viruses have well characterized genomes, allowing for substantial modifications including capsid chimeris
Externí odkaz:
https://doaj.org/article/c00c5fa258a94c68b67c51d7fc5f3b26
Publikováno v:
Nutrients, Vol 14, Iss 10, p 2008 (2022)
This systematic review and meta-analysis elucidate the effects of the Japanese-style diet and characteristic Japanese foods on the mortality risk of cardiovascular disease (CVD), cerebrovascular disease (stroke), and heart disease (HD). This review a
Externí odkaz:
https://doaj.org/article/562c8deb40594e7abe20a3026d339189
Publikováno v:
Cancers, Vol 12, Iss 3, p 619 (2020)
Oncolytic adenoviruses (OAd) selectively target and lyse tumor cells and enhance anti- tumor immune responses. OAds have been used as promising cancer gene therapies for many years and there are a multitude of encouraging pre-clinical studies. Howeve
Externí odkaz:
https://doaj.org/article/c4746ebfcd9a4f36be0d1663acfd4498