Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Masataka Shirai"'
Autor:
Yukari Kobayashi, Kazuhiro Kakimi, Koji Nagaoka, Akihiro Hosoi, Masataka Shirai, Kiyomi Taniguchi, Changbo Sun, Kazuhiro Maejima, Hidewaki Nakagawa, Sachiyo Nomura
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Although immune checkpoint blockade is effective for several malignancies, a substantial number of patients remain refractory to treatment. The future of immunotherapy will be a personalized approach adapted to each patient’s cancer-immu
Externí odkaz:
https://doaj.org/article/f5ca7f0c9947418783c99e9c179416ed
Autor:
Yukie Kashima, Ayako Suzuki, Ying Liu, Masahito Hosokawa, Hiroko Matsunaga, Masataka Shirai, Kohji Arikawa, Sumio Sugano, Takashi Kohno, Haruko Takeyama, Katsuya Tsuchihara, Yutaka Suzuki
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Abstract Single-cell RNA-seq is a powerful tool for revealing heterogeneity in cancer cells. However, each of the current single-cell RNA-seq platforms has inherent advantages and disadvantages. Here, we show that combining the different single-cell
Externí odkaz:
https://doaj.org/article/8f48ed8258fd4e5399c4358ae8f1ca6e
Autor:
Masashi Fujita, Kazuhiro Maejima, Koji Nagaoka, Changbo Sun, Akihiro Hosoi, Hidewaki Nakagawa, Yukari Kobayashi, Kazuhiro Kakimi, Kiyomi Taniguchi, Sachiyo Nomura, Masataka Shirai
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
BackgroundAlthough immune checkpoint blockade is effective for several malignancies, a substantial number of patients remain refractory to treatment. The future of immunotherapy will be a personalized approach adapted to each patient’s cancer-immun
Autor:
Weijian Jiang, Sarabjot Pabla, Vincent Giamo, Masataka Shirai, Sean T. Glenn, Kiyomi Taniguchi, Bowen Dong, Pawel Kalinski
Publikováno v:
Cancer Research. 80:968-968
Purpose of Study: Dendritic Cells (DC) maturing in the conditions of acute/early versus late/chronic inflammation (such as alpha-type-1-polarized DCs [αDC1s] and “standard” nonpolarized DCs; sDCs) deliver differential “signal 3” to resting T
Publikováno v:
Cancer Research. 80:1550-1550
BACKGROUND: YTN2 and YTN16 cells are chemically induced gastric cancer cell lines. YTN2 is spontaneously rejected in C57BL/6 mice in CD8+ T cell-dependent manner, while YTN16 grows progressively. To investigate the interaction of tumor microenvironme
Autor:
Vincent Giamo, Melissa Grimm, Sarabjot Pabla, Ellen Karasik, Jesse Luce, Sean T. Glenn, Jeffrey Conroy, Barbara Foster, Kiyomi Taniguchi, Pawel Kalinski, Masataka Shirai
Publikováno v:
Cancer Research. 80:970-970
Purpose of Study: Single-cell mRNAseq (scRNAseq) is a promising technology allowing for unbiased analysis of gene expression at the cellular level. In this study, scRNAseq was used to identify cellular sub-types and differential gene expression funct
Autor:
Sumio Sugano, Masahito Hosokawa, Masataka Shirai, Kohji Arikawa, Yukie Kashima, Haruko Takeyama, Katsuya Tsuchihara, Hiroko Matsunaga, Yutaka Suzuki, Takashi Kohno, Ying Liu, Ayako Suzuki
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Single-cell RNA-seq is a powerful tool for revealing heterogeneity in cancer cells. However, each of the current single-cell RNA-seq platforms has inherent advantages and disadvantages. Here, we show that combining the different single-cell RNA-seq p
Autor:
Mari Goto, Koji Arikawa, Hideki Kambara, Masataka Shirai, Huan Huang, Hiroyuki Tsunoda, Hiroko Matsunaga
Publikováno v:
Analytical Biochemistry. 471:9-16
Analyses of gene expressions in single cells are important for understanding detailed biological phenomena. Here, a highly sensitive and accurate method by sequencing (called “bead-seq”) to obtain a whole gene expression profile for a single cell
Publikováno v:
Biomedical Vibrational Spectroscopy 2016: Advances in Research and Industry.
Non-invasive cell analyses are increasingly important for medical field. A CARS microscope is one of the non-invasive imaging equipments and enables to obtain images indicating molecular distribution. Some studies on discrimination of cell state by u
Publikováno v:
Optics express. 23(3)
A compact light source module for ultrabroadband coherent anti-Stoke Raman scattering (CARS) microscopy was developed. It mainly consists of a nanosecond microchip laser, a photonic crystal fiber for Stokes light generation, and a single mode polariz