Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Masataka ODA"'
Autor:
Vindy Tjendana Tjhin, Masataka Oda, Masashi Yamashita, Tomoko Iwaki, Yasuko Fujita, Koji Wakame, Hiroyuki Inagawa, Gen-Ichiro Soma
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Some herbal extracts contain relatively high amounts of lipopolysaccharide (LPS). Because orally administered LPS activates innate immunity without inducing inflammation, it plays a role as an active ingredient in herbal extracts. However, t
Externí odkaz:
https://doaj.org/article/38a839e4e0964f369574dcc43ff796f8
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Immunotherapy is renowned for its capacity to elicit anti-infective and anti-cancer effects by harnessing immune responses to microbial components and bolstering innate healing mechanisms through a cascade of immunological reactions. Specifically, ma
Externí odkaz:
https://doaj.org/article/5498b84c3c434e669fdd6eac71c544e9
Autor:
Go Kamoshida, Takuya Akaji, Norihiko Takemoto, Yusuke Suzuki, Yoshinori Sato, Daichi Kai, Taishi Hibino, Daiki Yamaguchi, Takane Kikuchi-Ueda, Satoshi Nishida, Yuka Unno, Shigeru Tansho-Nagakawa, Tsuneyuki Ubagai, Tohru Miyoshi-Akiyama, Masataka Oda, Yasuo Ono
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Acinetobacter baumannii causes nosocomial infections due to its multidrug resistance and high environmental adaptability. Colistin is a polypeptide antibacterial agent that targets lipopolysaccharide (LPS) and is currently used to control serious mul
Externí odkaz:
https://doaj.org/article/e3310e94d20f427993094c95b0fcdbbf
Autor:
Hikaru Tamura, Tomoki Maekawa, Hisanori Domon, Takumi Hiyoshi, Satoru Hirayama, Toshihito Isono, Karin Sasagawa, Daisuke Yonezawa, Naoki Takahashi, Masataka Oda, Takeyasu Maeda, Koichi Tabeta, Yutaka Terao
Publikováno v:
Antibiotics, Vol 10, Iss 3, p 312 (2021)
Macrolides are used to treat various infectious diseases, including periodontitis. Furthermore, macrolides are known to have immunomodulatory effects; however, the underlying mechanism of their action remains unclear. DEL-1 has emerged as an importan
Externí odkaz:
https://doaj.org/article/f3eb2161cad648f7931b0eb5df5e52fa
Autor:
Atsushi Nakayama, Hideo Sato, Tenta Nakamura, Mai Hamada, Shuji Nagano, Shuhei Kameyama, Yui Furue, Naoki Hayashi, Go Kamoshida, Sangita Karanjit, Masataka Oda, Kosuke Namba
Publikováno v:
Marine Drugs, Vol 18, Iss 2, p 92 (2020)
Side-chain derivatives of eurotiumide A, a dihydroisochroman-type natural product, have been synthesized and their antimicrobial activities described. Sixteen derivatives were synthesized from a key intermediate of the total synthesis of eurotiumide
Externí odkaz:
https://doaj.org/article/29418da6412b417dae699a2c0a4e6107
Autor:
Hisanori Domon, Kosuke Nagai, Tomoki Maekawa, Masataka Oda, Daisuke Yonezawa, Wataru Takeda, Takumi Hiyoshi, Hikaru Tamura, Masaya Yamaguchi, Shigetada Kawabata, Yutaka Terao
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Excessive activation of neutrophils results in the release of neutrophil elastase (NE), which leads to lung injury in severe pneumonia. Previously, we demonstrated a novel immune subversion mechanism involving microbial exploitation of this NE abilit
Externí odkaz:
https://doaj.org/article/d0447f63407f409888e7955dbab58cab
Autor:
Naoki Hayashi, Yui Furue, Daichi Kai, Noriteru Yamada, Hirofumi Yamamoto, Takashi Nakano, Masataka Oda
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206696 (2018)
Pseudomonas aeruginosa is an opportunistic pathogen that causes severe infections, such as pneumonia and bacteremia. Several studies demonstrated that flagellar motility is an important virulence factor for P. aeruginosa infection. In this study, we
Externí odkaz:
https://doaj.org/article/34152ba2e2824ff8a9e09efd18522be8
Publikováno v:
Toxins, Vol 7, Iss 12, Pp 5268-5275 (2015)
Clostridium perfringens alpha-toxin is a key mediator of gas gangrene, which is a life-threatening infection that manifests as fever, pain, edema, myonecrosis, and gas production. Alpha-toxin possesses phospholipase C and sphingomyelinase activities.
Externí odkaz:
https://doaj.org/article/ecfb8a83b7874bcaa79e3a3858277268
Autor:
Masahiro Nagahama, Sadayuki Ochi, Masataka Oda, Kazuaki Miyamoto, Masaya Takehara, Keiko Kobayashi
Publikováno v:
Toxins, Vol 7, Iss 2, Pp 396-406 (2015)
Clostridium perfringens beta-toxin is a key mediator of necrotizing enterocolitis and enterotoxemia. It is a pore-forming toxin (PFT) that exerts cytotoxic effect. Experimental investigation using piglet and rabbit intestinal loop models and a mouse
Externí odkaz:
https://doaj.org/article/16b2225ea30241c28b62eb2dc9af1b86
Autor:
Masataka Oda, Hisanori Domon, Mie Kurosawa, Toshihito Isono, Tomoki Maekawa, Masaya Yamaguchi, Shigetada Kawabata, Yutaka Terao
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
The Streptococcus pyogenes phospholipase A2 (SlaA) gene is highly conserved in the M3 serotype of group A S. pyogenes, which often involves hypervirulent clones. However, the role of SlaA in S. pyogenes pathogenesis is unclear. Herein, we report that
Externí odkaz:
https://doaj.org/article/9070f4223dd2430187f1f606d464e2da