Effects on Metabolism in Astrocytes Caused by cGAMP, Which Imitates the Initial Stage of Brain Metastasis

Autor: Hiroki Tanaka, Hiromi Sato, Masataka Kogane, Hiroto Hatakeyama, Hidetaka Akita, Akihiro Hisaka, Toya Okawa, Momoko Goto, Kurumi Hara, Moe Kikuchi, Daiki Shirane

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 9028, p 9028 (2021)

The second messenger 2′3′-cyclic-GMP-AMP (cGAMP) is thought to be transmitted from brain carcinomas to astrocytes via gap junctions, which functions to promote metastasis in the brain parenchyma. In the current study, we established a method to i

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