Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Masataka Ito"'
Autor:
Masaru Takeuchi, Yoshiaki Nishio, Hideaki Someya, Tomohito Sato, Akihiko Yoshimura, Masataka Ito, Kozo Harimoto
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
PurposeInflammation is involved in the pathogenesis of diabetes, however the impact of diabetes on organ-specific autoimmune diseases remains unexplored. Experimental autoimmune uveoretinitis (EAU) is a widely accepted animal model of human endogenou
Externí odkaz:
https://doaj.org/article/0e9d3ea2fe8745e19f89699888440379
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 24, p 7742 (2023)
Vogt–Koyanagi–Harada disease (VKH) is an autoimmune disease, and glucocorticoid therapy (GC) is widely used for VKH. We provided a profile of leukocyte populations and serum cytokines in VKH patients under GC. A prospective observational study wa
Externí odkaz:
https://doaj.org/article/16dcd2235f484851b82f24f982e1c57b
Autor:
Masataka Ito, Hiroshi Yagasaki, Koji Kanezawa, Katsuyoshi Shimozawa, Maiko Hirai, Ichiro Morioka
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract Treatment of children with refractory immune thrombocytopenic purpura (ITP) is challenging and poorly established. We retrospectively reviewed the clinical data of 87 patients under the age of 16 years who were diagnosed with ITP from April
Externí odkaz:
https://doaj.org/article/533875f135bc4100955466d909261172
Autor:
Tomohito Sato, Rina Okazawa, Koichi Nagura, Hideaki Someya, Yoshiaki Nishio, Toshio Enoki, Masataka Ito, Masaru Takeuchi
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 6, p 2354 (2023)
Proliferative diabetic retinopathy (PDR) is a vision-threatening complication of diabetes mellitus (DM). Systemic and intraocular factors are intricately related to PDR, and vitreous fluid (VF) cytokines are representative intraocular biomarkers. How
Externí odkaz:
https://doaj.org/article/0b44c1e0085748c4ad051ac6a1076eff
Autor:
Hideyuki Shimizu, Kei Takayama, Kazuhisa Yamada, Ayana Suzumura, Tomohito Sato, Yoshiaki Nishio, Masataka Ito, Hiroaki Ushida, Koji M Nishiguchi, Masaru Takeuchi, Hiroki Kaneko
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 45 (2022)
The purpose of this study is to investigate the protective effect of dimethyl fumarate (DMF), the methyl-ester of fumaric acid, against blue-light (BL) exposure in retinal pigment epithelial (RPE) cells. ARPE-19 cells, a human RPE cell line, were cul
Externí odkaz:
https://doaj.org/article/99c08d040d5d40e8a078648940e76566
Autor:
Tomohito Sato, Toshio Enoki, Yoko Karasawa, Hideaki Someya, Manzo Taguchi, Kozo Harimoto, Kei Takayama, Takayuki Kanda, Masataka Ito, Masaru Takeuchi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundNeovascular age-related macular degeneration (nAMD) is a leading cause of blindness in older people. Low-grade inflammation is well-known as one of the pathogenic mechanisms in nAMD. Anti-vascular endothelial growth factor (VEGF) therapy is
Externí odkaz:
https://doaj.org/article/70568f7800634933bde6a3b5c7548bde
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1333 (2021)
The retinal pigment epithelium (RPE) is the major source of cytokines in the retina regulating the intraocular immune environment, and a primary target of photodamage. Here, we examined 27 types of cytokines secreted by ARPE-19 cells exposed to visib
Externí odkaz:
https://doaj.org/article/0b5fc317f71d48fb912e75631128852f
Autor:
Toshihiro Imada, Shigeru Nakamura, Ryuji Hisamura, Yusuke Izuta, Kai Jin, Masataka Ito, Naoki Kitamura, Kenji F. Tanaka, Masaru Mimura, Izumi Shibuya, Kazuo Tsubota
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Tears are extracellular fluid secreted from the lacrimal gland (LG). Tears consist of a dynamic tri-layered film composed of secretions from the LG, Meibomian gland, and conjunctival goblet cells. The LG secretes the aqueous component of the
Externí odkaz:
https://doaj.org/article/8662a0b15415419ab6535c6046909a18
Publikováno v:
BMC Ophthalmology, Vol 17, Iss 1, Pp 1-6 (2017)
Abstract Background Hyperkeratinization is a major cause of obstructive meibomian gland dysfunction (oMGD) and results in degenerative gland dilation and atrophy without inflammation. Ointment containing 1,25-dihydroxy-22-oxavitamin D3 (maxacalcitol)
Externí odkaz:
https://doaj.org/article/efb47546aa4449e79d7f7f13942df12f
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 1, p 6 (2020)
1α,-25-dihydroxy-22-oxacalcitriol (maxacalcitol) is a non-calcemic vitamin D3 analog clinically approved to treat psoriasis, and its role has been increasingly recognized in suppressing keratinocyte proliferation, mediating inflammation, and regulat
Externí odkaz:
https://doaj.org/article/e6875587efb7434c8c922359a9d76823