Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Masataka Chihara"'
Autor:
Yukie Kashima, Yosuke Togashi, Shota Fukuoka, Takahiro Kamada, Takuma Irie, Ayako Suzuki, Yoshiaki Nakamura, Kohei Shitara, Tatsunori Minamide, Taku Yoshida, Naofumi Taoka, Tatsuya Kawase, Teiji Wada, Koichiro Inaki, Masataka Chihara, Yukihiko Ebisuno, Sakiyo Tsukamoto, Ryo Fujii, Akihiro Ohashi, Yutaka Suzuki, Katsuya Tsuchihara, Hiroyoshi Nishikawa, Toshihiko Doi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Single-cell level analysis is powerful tool to assess the heterogeneity of cellular components in tumor microenvironments (TME). In this study, we investigated immune-profiles using the single-cell analyses of endoscopically- or surgically-r
Externí odkaz:
https://doaj.org/article/ed447e8d5e6c46eab303d092243a0a34
Autor:
Osamu Ichii, Masataka Chihara, Shin-Hyo Lee, Teppei Nakamura, Saori Otsuka-Kanazawa, Taro Horino, Yaser Hosny Ali Elewa, Yasuhiro Kon
Publikováno v:
Autoimmunity, Vol 50, Iss 2, Pp 114-124 (2017)
Inbred MRL/MpJ mice show several unique phenotypes in tissue regeneration processes and the urogenital and immune systems. Clarifying the genetic and molecular bases of these phenotypes requires the analysis of their genetic susceptibility locus. Her
Externí odkaz:
https://doaj.org/article/aa9702b627f44577900dfd21ad0b0480
Autor:
Teppei Nakamura, Masataka Chihara, Osamu Ichii, Saori Otsuka-Kanazawa, Ken-Ichi Nagasaki, Yaser Hosny Ali Elewa, Osamu Tatsumi, Yasuhiro Kon
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196364 (2018)
MRL/MpJ mice have abundant ovarian mast cells (MCs) as compared with other strains at postnatal day 0 (P0); however, they sharply decrease after birth. These ovarian MCs, particularly beneath the ovarian surface epithelium (SE), which express mucosal
Externí odkaz:
https://doaj.org/article/45bf29036d2c44d5a28cc93e5ec17623
Autor:
Teppei Nakamura, Yuko Sakata, Saori Otsuka-Kanazawa, Osamu Ichii, Masataka Chihara, Ken-ichi Nagasaki, Yuka Namiki, Yasuhiro Kon
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100617 (2014)
In MRL/MpJ mice, ovarian mast cells (OMCs) are more abundant than in other mouse strains, and tend to distribute beneath the ovarian surface epithelium at birth. This study investigated the factors regulating the appearance of neonatal OMCs in progen
Externí odkaz:
https://doaj.org/article/2f757fdae8ca467d9efa42b7f99fc50d
Autor:
Teiji Wada, Masataka Chihara, Shota Fukuoka, Hiroyoshi Nishikawa, Toshihiko Doi, Taku Yoshida, Koichiro Inaki, Katsuya Tsuchihara, Tatsuya Kawase, Akihiro Ohashi, Takahiro Kamada, Kohei Shitara, Yukie Kashima, Yukihiko Ebisuno, Yoshiaki Nakamura, Takuma Irie, Naofumi Taoka, Ayako Suzuki, Sakiyo Tsukamoto, Ryo Fujii, Yutaka Suzuki, Tatsunori Minamide, Yosuke Togashi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Single-cell level analysis is powerful tool to assess the heterogeneity of cellular components in tumor microenvironments (TME). In this study, we investigated immune-profiles using the single-cell analyses of endoscopically- or surgically-resected t
Autor:
Hiroki Yamashita, Yoshiaki Nakamura, Yutaka Suzuki, Hiroaki Tanaka, Kohei Shitara, Taku Yoshida, Tomonori Yano, Syohei Koyama, Tatsunori Minamide, Kazuho Nishimura, Masataka Chihara, Toshihiko Doi, Koichiro Inaki, Hiroyoshi Nishikawa, Ayako Suzuki, Katsuya Tsuchihara, Akito Nakamura, Akihiro Ohashi, Yukie Kashima, Takuma Irie, Yosuke Togashi, Saomi Murai, Teiji Wada
Publikováno v:
Gastroenterology. 160:S-623
Autor:
Yutaka Suzuki, Teiji Wada, Naofumi Taoka, Kocihiro Inaki, Yukie Kashima, Akihiro Ohashi, Susumu Kobayashi, Takahiro Kamada, Shota Fukuoka, Toshihiko Doi, Tatsuya Kawase, Yoshiaki Nakamura, Masataka Chihara, Kohei Shitara, Taku Yoshida, Yosuke Togashi, Hiroyoshi Nishikawa, Katsuya Tsuchihara, Ayako Suzuki
Publikováno v:
Molecular Cancer Therapeutics. 18:C113-C113
Background: Tumor tissues are composed of heterogeneous populations, including cancer cells, immune cells, and stromal cells. These cells are spatiotemporally interacted and play critical roles in tumor development. To understand the complexity of th
Autor:
Masataka Chihara, Kozue Sotozaki, Hirokazu Kouguchi, Yuji Sunden, Teppei Nakamura, Ken-ichi Nagasaki, Osamu Tatsumi, Yaser Hosny Ali Elewa, Yasuhiro Kon, Takao Irie, Osamu Ichii
Publikováno v:
Cell and tissue research. 375(2)
Obesity induces metabolic disorders such as type 2 diabetes, hypertension, and cardiovascular diseases and has become a global health concern. Recent studies imply that fat accumulation in nonadipose tissue correlates with metabolic disorders. Howeve
Autor:
Saori Otsuka-Kanazawa, Masataka Chihara, Ken-ichi Nagasaki, Teppei Nakamura, Osamu Ichii, Yaser Hosny Ali Elewa, Yasuhiro Kon, Osamu Tatsumi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 4, p e0196364 (2018)
PLoS ONE, Vol 13, Iss 4, p e0196364 (2018)
MRL/MpJ mice have abundant ovarian mast cells (MCs) as compared with other strains at postnatal day 0 (P0); however, they sharply decrease after birth. These ovarian MCs, particularly beneath the ovarian surface epithelium (SE), which express mucosal
Autor:
Osamu Ichii, Teppei Nakamura, Yasuhiro Kon, Saori Otsuka-Kanazawa, Yuki Otani, Masataka Chihara
Publikováno v:
Autoimmunity. 48:402-411
The immune system is known to affect reproductive function, and maternal-fetal immune tolerance is essential for a successful pregnancy. To investigate the relationship between autoimmune disease and female reproductive function, we performed a compa