Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Masashige Bando"'
Autor:
Ryuichiro Nakato, Toyonori Sakata, Jiankang Wang, Luis Augusto Eijy Nagai, Yuya Nagaoka, Gina Miku Oba, Masashige Bando, Katsuhiko Shirahige
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Cohesin regulates gene expression through context-specific chromatin folding mechanisms such as enhancer–promoter looping and topologically associating domain (TAD) formation by cooperating with factors such as cohesin loaders and the insu
Externí odkaz:
https://doaj.org/article/c8c4bd7a93544e569e01c4b985edce97
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Cohesin complex is essential for transcriptional regulation and chromosome folding. Here the authors provide a large-scale multi-omics analysis suggesting that cohesin bound on gene bodies has a specific role in transcriptional regulation.
Externí odkaz:
https://doaj.org/article/b2c4f7cfab4041a894738fdd1fbc2be3
Autor:
Ioana Olan, Aled J. Parry, Stefan Schoenfelder, Masako Narita, Yoko Ito, Adelyne S. L. Chan, Guy St.C. Slater, Dóra Bihary, Masashige Bando, Katsuhiko Shirahige, Hiroshi Kimura, Shamith A. Samarajiwa, Peter Fraser, Masashi Narita
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Senescence is a state of stable proliferative arrest. Here, the authors perform Hi-C analysis on oncogenic RAS-induced senescence in human fibroblasts and characterize the changes in the 3D genome folding associated with the senescence-specific gene
Externí odkaz:
https://doaj.org/article/cfcc6e6ce1f94a00978bd38e7e46977b
Autor:
Junji Koya, Keisuke Kataoka, Tomohiko Sato, Masashige Bando, Yuki Kato, Takako Tsuruta-Kishino, Hiroshi Kobayashi, Kensuke Narukawa, Hiroyuki Miyoshi, Katsuhiko Shirahige, Mineo Kurokawa
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
DNMT3A mutations are known to cause acute myeloid leukaemia. Here, Koya et al. show that DNMT3A R882H mutation causes monoblastic transformation and haematopoietic stem cell accumulation in a methylation-independent manner, by suppressing the polycom
Externí odkaz:
https://doaj.org/article/3b5a176a67f947c3b5e27931bbee2280
Autor:
Jinglan Liu, Zhe Zhang, Masashige Bando, Takehiko Itoh, Matthew A Deardorff, Dinah Clark, Maninder Kaur, Stephany Tandy, Tatsuro Kondoh, Eric Rappaport, Nancy B Spinner, Hugo Vega, Laird G Jackson, Katsuhiko Shirahige, Ian D Krantz
Publikováno v:
PLoS Biology, Vol 7, Iss 5, p e1000119 (2009)
Cohesin regulates sister chromatid cohesion during the mitotic cell cycle with Nipped-B-Like (NIPBL) facilitating its loading and unloading. In addition to this canonical role, cohesin has also been demonstrated to play a critical role in regulation
Externí odkaz:
https://doaj.org/article/07391626c2d540a2bf2e7dfb3880f66c
Autor:
Yosuke Masamoto, Akira Chiba, Hideaki Mizuno, Toshiya Hino, Hiroki Hayashida, Tomohiko Sato, Masashige Bando, Katsuhiko Shirahige, Mineo Kurokawa
Publikováno v:
Blood Advances. 7:1577-1593
Aberrant expression of ecotropic viral integration site-1 (EVI1+) is associated with very poor outcomes in acute myeloid leukemia (AML), mechanisms of which are only partially understood. Using the green fluorescent protein reporter system to monitor
Autor:
Miwako Kato Homma, Ryuichiro Nakato, Atsushi Niida, Masashige Bando, Katsunori Fujiki, Naoko Yokota, So Yamamoto, Takeshi Shibata, Motoki Takagi, Junko Yamaki, Hiroko Kozuka-Hata, Masaaki Oyama, Katsuhiko Shirahige, Yoshimi Homma
Publikováno v:
Life Science Alliance; Jan2024, Vol. 7 Issue 1, p1-18, 18p
Autor:
Ryuichiro Nakato, Toyonori Sakata, Jiankang Wang, Luis Augusto Eijy Nagai, Gina Miku Oba, Masashige Bando, Katsuhiko Shirahige
Cohesin plays vital roles in chromatin folding and gene expression regulation, cooperating with such factors as cohesin loaders, unloaders, acetyltransferase, and the insulation factor CTCF. Although various models of regulation have been proposed (e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4507a0bc7c23c13a3e39a57733d5075f
https://doi.org/10.1101/2022.05.24.493188
https://doi.org/10.1101/2022.05.24.493188
Publikováno v:
Nature communications. 13(1)
Cohesin, an essential protein complex for chromosome segregation, regulates transcription through a variety of mechanisms. It is not a trivial task to genome-widely assign the diverse cohesin functions. Moreover, the context-specific roles of cohesin
Autor:
Sangmoon Lee, Ryojun Takeda, Nataliya Di Donato, Masashige Bando, Darina Prchalova, Mathieu Quesnel-Vallières, Seiji Mizuno, Naomichi Matsumoto, Koji Masuda, Miroslava Hancarova, Margaret Harr, Karl Hackmann, Zdenek Sedlacek, Alica Valachova, Alyssa Ritter, Eriko Nishi, Tommaso Pippucci, Michiko Arakawa, Katsuhiko Shirahige, Katsunori Fujiki, Elaine H. Zackai, Noriko Miyake, Marketa Vlckova, Ryuichiro Nakato, Aiko Iwata-Otsubo, Yoseph Barash, Christoph Seiler, Dong Li, Beth Keena, Nobuhiko Okamoto, Kosuke Izumi, Jung Min Ko, Sarah K. Fiordaliso, Elizabeth J. Bhoj, Hakon Hakonarson, Murim Choi, Jenny Morton
Publikováno v:
Am J Hum Genet
NKAP is a ubiquitously expressed nucleoplasmic protein that is currently known as a transcriptional regulatory molecule via its interaction with HDAC3 and spliceosomal proteins. Here, we report a disorder of transcriptional regulation due to missense