Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Masashi Yasuba"'
Autor:
Yoshiko Michimae, Toru Yamada, Toru Kimura, Takaki Seki, Tadashi Inoue, Mami Kouchi, Okio Hino, Masashi Yasuba, Kazuo Okimoto, Izumi Matsumoto
Publikováno v:
Experimental and Toxicologic Pathology. 59:273-279
Fibromatosis-type fibromas were found to develop at abdominal surgical sites in 4 heterozygous Nihon rats, a model for the human Birt–Hogg–Dube syndrome. In all 4 rats, solitary and firm nodules were located within the lateral abdominal musculatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6db823ec75fb3f181f1a2bf70565594
https://doi.org/10.1016/j.etp.2007.10.005
https://doi.org/10.1016/j.etp.2007.10.005
Autor:
Masatoshi Komiyama, Tetsuya Adachi, Kazuyasu Kijima, Kaoru Toyosawa, Masashi Yasuba, Chisato Mori, Nobuo Matsuoka
Publikováno v:
Toxicology and Applied Pharmacology. 200:103-110
To investigate the effects of di(2-ethylhexyl) phthalate (DEHP) on gene expression in rat testis, 6-week-old male Sprague-Dawley rats were given a single oral dose of 20 or 2000 mg/kg and euthanized 3, 6, 24, or 72 h thereafter. Terminal deoxynucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254539a029a3c05e6b8499fd9fadbaa0
https://doi.org/10.1016/j.taap.2004.03.015
https://doi.org/10.1016/j.taap.2004.03.015
Autor:
Yuji Kubo, Toshihiro Maeda, Hidetoshi Oishi, Keiji Sekiya, Takatoshi Koujitani, Masashi Yasuba, Koichi Nishimura, Nobuo Matsuoka
Publikováno v:
International Journal of Toxicology. 16:611-623
Toxicity studies were conducted to evaluate acute and subchronic oral toxicity and mutagenicity of partially hydrolyzed guar gum (K-13). In an acute toxicity study, mice and rats were treated with K-13 at a dose of 6000 mg/ kg. There were no deaths,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62d093b696da79aa99cf1e86a05f622d
https://doi.org/10.1080/109158197226928
https://doi.org/10.1080/109158197226928
Publikováno v:
Journal of Toxicologic Pathology. 8:435-439
This paper describes spontaneous ovarian choriocarcinoma in two B6C3F1 mice used in toxicity studies. One animal (case 1) was sacrificed at eight weeks of age, and the other one (case 2) was found dead at sixty-seven weeks of age. Macroscopically, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4e9bf206a5db8d9f93ddb7fe5d9d7aa
https://doi.org/10.1293/tox.8.435
https://doi.org/10.1293/tox.8.435
Publikováno v:
Journal of Toxicologic Pathology. 6:251-256
Spontaneous true hermaphroditism in a rat is reported. This animal was a unilateral hermaphrodite composed of a testis on the left and an ovotestis on the right, although the external genitalia was masculine. In the present case, there were epididymi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dff3936799e8c3c23cb8e8eee3f6a3f
https://doi.org/10.1293/tox.6.251
https://doi.org/10.1293/tox.6.251
Autor:
Kohji Tanaka, Takatoshi Koujitani, Kazuo Okimoto, Emi Kikawa, Mami Irie, Kaoru Toyosawa, Masashi Yasuba
Publikováno v:
Journal of Toxicologic Pathology. 10:63-65
Granular cell tumors were found in 18 female reproductive tract out of 300 Wistar rats. The tumor cells were histologically polygonal and arranged in sheets or cords separated from each other by collagenous septa. The cytoplasm was filled with period
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5671cabda56617ee276dc21b25dcc71
https://doi.org/10.1293/tox.10.63
https://doi.org/10.1293/tox.10.63
Publikováno v:
Virchows Archiv : an international journal of pathology. 448(4)
In the Nihon rat, an established model of hereditary renal cell carcinoma (RCC), the propensity for tumor development, is inherited as an autosomal dominant trait due to a single germline nucleotide insertion mutation in the rat Bhd ortholog. The Bir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf39ac6a317923f5d5432fd8ef38cf7
https://pubmed.ncbi.nlm.nih.gov/16447066
https://pubmed.ncbi.nlm.nih.gov/16447066
Publikováno v:
Toxicology letters. 145(3)
In order to elucidate the mechanisms by which long-term treatment with clobazam (CLB), 1,5-benzodiazepine, induces thyroid follicular cell tumors in male rats, male Sprague-Dawley (SD) rats were treated orally with 400 mg/kg of CLB for up to 4 weeks,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31666e154f86cbd1d54a25b4f090bd0c
https://pubmed.ncbi.nlm.nih.gov/14580900
https://pubmed.ncbi.nlm.nih.gov/14580900
Autor:
Toshiki Sumiya, Masuo Kurono, Akihisa Ikeno, Yoshinobu Masuda, Masashi Yasuba, Kanoo Hosoki, Hisao Minato, Buichi Fujitani
Publikováno v:
Japanese journal of pharmacology. 78(3)
The mechanism of the prophylactic effect against hyperlipidemia by monatepil maleate was investigated in animal models. Monatepil maleate is an antihypertensive agent with Ca2+-channel antagonistic, alpha1-adrenergic receptor-blocking, and lipid pero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e855e9071a531e551f8d691c1bc6b8
https://pubmed.ncbi.nlm.nih.gov/9869264
https://pubmed.ncbi.nlm.nih.gov/9869264
Natural history of the Nihon (Bhd gene mutant) rat, a novel model for human Birt–Hogg–Dubé syndrome.
Publikováno v:
Virchows Archiv: European Journal of Pathology; Apr2006, Vol. 448 Issue 4, p463-471, 9p