Výsledky vyhledávání - "Masashi Takamatsu"

Generation of 1,25-dihydroxyvitamin D3 in Cyp27b1 knockout mice by treatment with 25-hydroxyvitamin D3 rescued their rachitic phenotypes

Autor: Keisuke Abe, Naoko Tsugawa, Shigeaki Yamashita, Kazuma Tanaka, Toshiyuki Sakaki, Masashi Takamatsu, Kaori Yasuda, Tatsuo Suda, Kimie Nakagawa, Miyu Nishikawa, Shinichi Ikushiro, Toshio Okano, Yoshihisa Hirota

Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 185:71-79

We have reported that 25-hydroxyvitamin D3 [25(OH)D3] binds to vitamin D receptor and exhibits several biological functions directly in vitro. To evaluate the direct effect of 25(OH)D3 in vivo, we used Cyp27b1 knockout (KO) mice, which had no detecta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::46cd0167de49bb7f4d941988c25e9727
https://doi.org/10.1016/j.jsbmb.2018.07.012

Zobrazit plný text záznamu

Generation of novel genetically modified rats to reveal the molecular mechanisms of vitamin D actions

Autor: Keisuke Abe, Toshiyuki Sakaki, Kaori Yasuda, Eiichi Hinoi, Miyu Nishikawa, Toshio Okano, Yoshihisa Hirota, Naoko Tsugawa, Masashi Takamatsu, Kairi Okamoto, Kyohei Horibe, Shinichi Ikushiro, Hiroki Mano, Kimie Nakagawa, Tetsuhiro Horie

Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)

Recent studies have suggested that vitamin D activities involve vitamin D receptor (VDR)-dependent and VDR-independent effects of 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) and 25-hydroxyvitamin D3 (25(OH)D3) and ligand-independent effects of the VDR.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92a3c59542cbd24474de7b46418da87
http://europepmc.org/articles/PMC7105495

Zobrazit plný text záznamu

In vitro selection of a 3' terminal short protector that stabilizes transcripts to improve the translation efficiency in a wheat germ extract

Autor: Atsushi Ogawa, Tatsuya Okuzono, Akane Kutsuna, Masashi Takamatsu

Publikováno v: Bioorganicmedicinal chemistry letters. 29(16)

Wheat cell-free expression systems based on wheat germ extract (WGE) enable us to briefly synthesize various types of proteins in vitro merely by exogenously adding their mRNA templates. Moreover, it is possible to produce larger amounts of protein b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cee0634372c8421df66af65897ee26b
https://pubmed.ncbi.nlm.nih.gov/31278030

Zobrazit plný text záznamu

Biofunction-assisted DNA detection through RNase H-enhanced 3′ processing of a premature tRNA probe in a wheat germ extract

Autor: Atsushi Ogawa, Junichiro Tabuchi, Masashi Takamatsu, Yasunori Doi

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 26:3658-3661

We have developed a novel type of biofunction-assisted, signal-turn-on sensor for simply and homogenously detecting DNA. This sensor system is composed of two types of in vitro-transcribed label-free RNAs (a 3' premature amber suppressor tRNA probe a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1e1d768d46932779c87051e8f1a68f
https://doi.org/10.1016/j.bmcl.2016.05.091

Zobrazit plný text záznamu

Mutation of the start codon to enhance Cripavirus internal ribosome entry site-mediated translation in a wheat germ extract

Autor: Atsushi Ogawa, Masashi Takamatsu

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 29:126729

Wheat germ extract (WGE) is one of the most widely used eukaryotic cell-free translation systems for easy synthesis of a broad range of proteins merely by adding template mRNAs. Its productivity has thus far been improved by removing translational in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77896e9b379d2d6e12bc0209c4254314
https://doi.org/10.1016/j.bmcl.2019.126729

Zobrazit plný text záznamu

Polymyositis associated with autoimmune hepatitis, primary biliary cirrhosis, and autoimmune thrombocytopenic purpura

Autor: Yutaka Okano, Takashi Shishido, Yuko Kurihara, Toshihito Shinagawa, Masashi Takamatsu, Hiroshi Ishiguro, Takao Fujii, Tadayuki Ishihara, Tsunejirou Sekita, Ran Nakashima, Kayo Oku, Atsushi Suzuki

Publikováno v: Modern Rheumatology. 21:325-329

We describe a 40-year-old woman with polymyositis (PM) who developed autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and autoimmune thrombocytopenic purpura (AITP) concurrently. About 4 years earlier, she suffered from muscle weakness pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d7380f6726d6582dae6803495ac5fe0
https://doi.org/10.3109/s10165-010-0397-0

Zobrazit plný text záznamu

A juvenile female case of liver cirrhosis found by the chance of an oral administration of turmeric

Autor: Yoshihiko Naito, Masashi Takamatsu, Yoko Kasuga, Masaru Takagi, Minoru Niiya, Shiro Maeyama, Taira Zenitani, Kiyotaka Fujise, Kenji Suzuki, Takashi Araki

Publikováno v: Kanzo. 47:310-315

症例は18歳女性．生来健康だったが，ウコン，女性ホルモン剤を内服していたところ黄疸，肝障害を認めた．肝生検では形質細胞浸潤，ロゼット形成を伴う肝硬変像を呈し，実質には著�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9fb1b85efd87c5539719d903ed23f3d6
https://doi.org/10.2957/kanzo.47.310

Zobrazit plný text záznamu

Experimental Studies on the Relationship Between Immune Responses and Liver Damage Induced by Ethanol After Immunization With Homologous Acetaldehyde Adducts

Autor: Mitsuru Ohata, Masashi Takamatsu, Saburo Saito, Masayoshi Yamauchi, Seika Shimada, Shinichiro Uetake

Publikováno v: Alcoholism: Clinical and Experimental Research. 26:86s-90s

Background: It has been considered that acetaldehyde (AcH) adducts induce liver injury through an immune response. Previous experimental studies showed that hepatic necrosis, inflammatory cell infiltration, and hepatic fibrosis were induced in guinea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e9fa00074fd696188160e7951b49ac
https://doi.org/10.1111/j.1530-0277.2002.tb02709.x

Zobrazit plný text záznamu

Polymorphism of Tumor Necrosis Factor-beta and Alcohol Dehydrogenase Genes and Alcoholic Brain Atrophy in Japanese Patients

Autor: Masaru Takagi, Gotaro Toda, Masashi Takamatsu, Masayoshi Yamauchi, Yoshihiko Maezawa, Shunnya Satoh, Saburo Saito, Takashi Araki

Publikováno v: Alcoholism: Clinical and Experimental Research. 25:7S-10S

Background: Alcohol abuse can induce brain atrophy, but it only occurs in some alcoholics. Many inflammatory cytokines such as tumor necrosis factor (TNF) are produced rapidly in the brain by experimental or clinical injury. Method: To investigate wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aaa486dc20f94bf0c266af4b2b578d4
https://doi.org/10.1111/j.1530-0277.2001.tb02409.x

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání